Search Results - "Gensaku Okada"

Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines in in vitro culture by Okada, Gensaku, Watanabe, Hiroyuki, Ohtsubo, Koushiro, Mouri, Hisatsugu, Yamaguchi, Yasushi, Motoo, Yoshiharu, Sawabu, Norio

“…Since telomerase expression is highly prevalent in human cancers, the quantitation of serum/plasma hTERT (human telomerase reverse transcriptase) mRNA levels…”
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Diagnostic utility of aberrant methylation of tissue factor pathway inhibitor 2 in pure pancreatic juice for pancreatic carcinoma by Jiang, PeiHong, Watanabe, Hiroyuki, Okada, Gensaku, Ohtsubo, Koushiro, Mouri, Hisatsugu, Tsuchiyama, Tomoya, Yao, Fan, Sawabu, Norio

“…The tissue factor pathway inhibitor 2 (TFPI‐2) is a Kunitz‐type serine proteinase inhibitor. Recently, the aberrant methylation of TFPI‐2 was detected…”
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Preproenkephalin hypermethylation in the pure pancreatic juice compared with p53 mutation in the diagnosis of pancreatic carcinoma by Ohtsubo, Koushiro, Watanabe, Hiroyuki, Yao, Fan, Okada, Gensaku, Mouri, Hisatsugu, Yamaguchi, Yasushi, Sawabu, Norio

“…Aberrant methylation of CpG islands is a common mechanism for the dysregulation of tumor suppressor genes in a variety of human malignancies. Preproenkephalin…”
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Expression of mesothelin mRNA in pure pancreatic juice from patients with pancreatic carcinoma, intraductal papillary mucinous neoplasm of the pancreas, and chronic pancreatitis by Watanabe, Hiroyuki, Okada, Gensaku, Ohtsubo, Koushiro, Yamaguchi, Yasushi, Mouri, Hisatsugu, Motoo, Yoshiharu, Wakabayashi, Tokio, Sawabu, Norio

“…In the gene expression analysis of pancreatic carcinoma (PCa) using serial analysis of gene expression (SAGE) according to Ryu et al, the tag for the…”
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Expression of vacuole membrane protein 1 (VMP1) in spontaneous chronic pancreatitis in the WBN/Kob rat by Jiang, Pei-Hong, Motoo, Yoshiharu, Vaccaro, María Inés, Iovanna, Juan Lucio, Okada, Gensaku, Sawabu, Norio

“…VMP1 is a stress-induced gene that is overexpressed in acute pancreatitis. Its overexpression promotes the formation of intracellular vacuoles and cell death…”
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Application of the polymerase chain reaction (PCR) to quantify micro-metastasis in an experimental animal by Matano, Sadaya, Ryoyama, Kazuo, Nakamura, Shinobu, Okada, Gensaku, Nomura, Takahiro

“…In vitro cultured r/ mHM-SFME-1 cells were injected into the hind foot pads of Balb/c mice. Metastasis was detected in the lungs of tumor-bearing mice by means…”
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Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines in in vitro culture by Okada, Gensaku, Watanabe, Hiroyuki, Ohtsubo, Koushiro, Mouri, Hisatsugu, Yamaguchi, Yasushi, Motoo, Yoshiharu, Sawabu, Norio

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Establishment of a Metastatic Murine Cell Line Carrying the Human c-Ha-Ras by Takahiro Nomura, Sadaya Matano, Gensaku Okada, Haruhiko Tokuyama, Hori, Isao, Shinobu Nakamura, Kameyama, Tadanori, Ryoyama, Kazuo

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A$MER^-$Phenotype of Ethionine-Resistant Hela S3 Variants by Gensaku Okada, Santi Reungmaneepaitoon, Nakano, Kazushiro, Takahiro Nomura, Haruhiko Tokuyama, Ryoyama, Kazuo, Yamaguchi, Kazuo, Kameyama, Tadanori

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Aberrant methylation of secreted apoptosis-related protein 2 (SARP2) in pure pancreatic juice in diagnosis of pancreatic neoplasms by Watanabe, Hiroyuki, Okada, Gensaku, Ohtsubo, Koushiro, Yao, Fan, Jiang, Pei-Hong, Mouri, Hisatsugu, Wakabayashi, Tokio, Sawabu, Norio

“…Secreted apoptosis-related protein (SARP) families are considered to counteract the oncogenic Wnt signaling pathway, and inactivation of this gene may aid…”
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Nicotinamide Starvation and Inhibition of Poly (ADP-Ribose) Synthesis Enhance the Induced Mutation in Chinese Hamster V79 Cells by Okada, G, Mitsui, H, Kaneko, I

“…The effects of nicotinamide (NA) deficiency and added NA and 3-aminobenzarnide (3AB) on the cytotoxicity and the induction of mutations in Chinese hamster…”
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Immunological distinction of S-adenosylmethionine synthetase isozymes from rat liver and kidney by Abe, T, Okada, G, Teraoka, H, Tsukada, K

“…The beta-form of S-adenosylmethionine synthetase among three isozymes has been purified from rat liver, and proven to be homogeneous. The molecular weight of…”
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A case of pancreatic cancer with formation of a mass mimicking alcoholic or autoimmune pancreatitis in a young man. Possibility of diagnosis by hypermethylation of pure pancreatic juice by Ohtsubo, Koushiro, Watanabe, Hiroyuki, Okada, Gensaku, Tsuchiyama, Tomoya, Mouri, Hisatsugu, Yamaguchi, Yasushi, Motoo, Yoshiharu, Okai, Takashi, Amaya, Koji, Kitagawa, Hirohisa, Ohta, Tetsuo, Gabata, Toshifumi, Matsuda, Koichiro, Ohta, Hideki, Sawabu, Norio

“…Mass-forming pancreatitis can be divided into two distinct types: alcoholic and autoimmune. There have been some cases of an ambiguous diagnosis although care…”
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Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma by Tsuchiya, H, Mori, Y, Ueda, Y, Okada, G, Tomita, K

“…The present study was performed to investigate whether the introduction of a wild-type p53 gene into human osteosarcoma cells could alter the growth rate and…”
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Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas by Jiang, Pei-Hong, Motoo, Yoshiharu, Iovanna, Juan Lucio, Pébusque, Marie-Josèphe, Xie, Min-Jue, Okada, Gensaku, Sawabu, Norio

“…The tumor protein p53-induced nuclear protein 1 (TP53INP1) gene was found using DNA microarray technology as an overexpressed gene in acute pancreatitis…”
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Carcinogen-induced de novo methylation in c-myc exon I by Okada, G, Ryoyama, K, Nomura, T, Momoi, T, Tsuchiya, H, Kameyama, T, Yamaguchi, K

“…During the response of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), methylation occurred at the Hpa II site of c-myc exon I, which is located downstream of the…”
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Plasminogen activator inhibitor-1 accelerates lung metastasis formation of human fibrosarcoma cells by Tsuchiya, H, Sunayama, C, Okada, G, Matsuda, E, Tomita, K, Binder, B R

“…We have studied the effects of PAI-1 on the formation of metastasis using human fibrosarcoma cells and DNA transfection. A clone (1-3C), which shows low…”
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Multiple species of mammalian S-adenosylmethionine synthetase. Partial purification and characterization by Okada, Gensaku, Teraoka, Hirobumi, Tsukada, Kinji

“…Two species of S-adenosylmethionine (S-Ado-Met) synthetase (EC 2.5.1.6) exist in rat liver cytosol and a distinct species of the enzyme exists in kidney…”
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S-Adenosylmethionine synthetase isozyme patterns from rat hepatoma induced by N-2-fluorenylacetamide by Tsukada, K, Okada, G

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Non‐transformed, but not ras/myc‐transformed, Serum‐free Mouse Embryo Cells Recover from Growth Suppression by Azatyrosine by Nomura, Takahiro, Ryoyama, Kazuo, Okada, Gensaku, Matano, Sadaya, Nakamura, Shinobu, Kameyama, Tadanori

“…The anti‐proliferative effect of azatyrosine, a newly discovered antibiotic from Streptomyces, was examined in Balb/c‐originated serum‐free mouse embryo (SFME)…”
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