Search Results - "Genovesi, Eugene V."

Orally Active Fusion Inhibitor of Respiratory Syncytial Virus by Cianci, Christopher, Yu, Kuo-Long, Combrink, Keith, Sin, Ny, Pearce, Bradley, Wang, Alan, Civiello, Rita, Voss, Stacey, Luo, Guangxiang, Kadow, Kathy, Genovesi, Eugene V, Venables, Brian, Gulgeze, Hatice, Trehan, Ashok, James, Jennifer, Lamb, Lucinda, Medina, Ivette, Roach, Julia, Yang, Zheng, Zadjura, Lisa, Colonno, Richard, Clark, Junius, Meanwell, Nicholas, Krystal, Mark

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Long-Term Entecavir Treatment Results in Sustained Antiviral Efficacy and Prolonged Life Span in the Woodchuck Model of Chronic Hepatitis Infection by Colonno, Richard J., Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Durham, Stephen K., Huang, Meei-Li, Corey, Lawrence, Littlejohn, Margaret, Locarnini, Steven, Tennant, Bud C., Rose, Burt, Clark, Junius M.

“…Entecavir (ETV) is a guanosine nucleoside analogue with potent antiviral efficacy in woodchucks chronically infected with woodchuck hepatitis virus. To explore…”
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Oral Efficacy of a Respiratory Syncytial Virus Inhibitor in Rodent Models of Infection by CIANCI, Christopher, GENOVESI, Eugene V, COMBRINK, Keith, ZHUFANG LI, COLONNO, Richard, MEANWELL, Nicholas, CLARK, Junius, KRYSTAL, Mark, LAMB, Lucinda, MEDINA, Ivette, ZHENG YANG, ZADJURA, Lisa, HYEKYUNG YANG, D'ARIENZO, Celia, NY SIN, YU, Kuo-Long

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Respiratory syncytial virus fusion inhibitors. Part 7: Structure–activity relationships associated with a series of isatin oximes that demonstrate antiviral activity in vivo by Sin, Ny, Venables, Brian L., Combrink, Keith D., Gulgeze, H. Belgin, Yu, Kuo-Long, Civiello, Rita L., Thuring, Jan, Wang, X. Alan, Yang, Zheng, Zadjura, Lisa, Marino, Anthony, Kadow, Kathleen F., Cianci, Christopher W., Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Krystal, Mark, Meanwell, Nicholas A.

“…A series of bezimidazole-isatin oximes were prepared and profiled as inhibitors of respiratory syncytial virus (RSV) replication in cell culture…”
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Respiratory syncytial virus fusion inhibitors. Part 4: Optimization for oral bioavailability by Yu, Kuo-Long, Sin, Ny, Civiello, Rita L., Wang, X. Alan, Combrink, Keith D., Gulgeze, H. Belgin, Venables, Brian L., Wright, J.J. Kim, Dalterio, Richard A., Zadjura, Lisa, Marino, Anthony, Dando, Sandra, D’Arienzo, Celia, Kadow, Kathleen F., Cianci, Christopher W., Li, Zhufang, Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Colonno, Richard J., Yang, Zheng, Krystal, Mark, Meanwell, Nicholas A.

“…A series of benzimidazole-based inhibitors of respiratory syncytial virus (RSV) fusion were optimized for antiviral potency, membrane permeability and…”
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Respiratory syncytial virus fusion inhibitors. Part 6: An examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety by Combrink, Keith D., Gulgeze, H. Belgin, Thuring, Jan W., Yu, Kuo-Long, Civiello, Rita L., Zhang, Yi, Pearce, Bradley C., Yin, Zhiwei, Langley, David R., Kadow, Kathleen F., Cianci, Christopher W., Li, Zhufang, Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Yang, Zheng, Zadjura, Lisa, Krystal, Mark, Meanwell, Nicholas A.

“…The effect of structural variation of the benzimidazol-2-one ring of RSV fusion inhibitors related to BMS-433771 ( 1) was examined in conjunction with side…”
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Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo by Yu, Kuo-Long, Wang, Xiangdong Alan, Civiello, Rita L., Trehan, Ashok K., Pearce, Bradley C., Yin, Zhiwei, Combrink, Keith D., Gulgeze, H. Belgin, Zhang, Yi, Kadow, Kathleen F., Cianci, Christopher W., Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Wyde, Philip R., Krystal, Mark, Meanwell, Nicholas A.

“…The introduction of acidic and basic functionality into the side chains R and R′ of respiratory syncytial virus (RSV) fusion inhibitors 2 was examined in an…”
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Adoptive transfer of antiviral resistance by lymphoid cells from mice protected against Friend leukemia virus-induced disease by passive serum therapy by Collins, J J, Genovesi, E V, Livnat, D, Sanfilippo, F

“…Spleen and bone marrow cells from DBA/2 mice protected against infection with a leukemogenic dose of Friend leukemia virus (FLV) by passive therapy with…”
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Use of adoptive transfer and Winn assay procedures in the further analysis of antiviral acquired immunity in mice protected against Friend leukemia virus-induced disease by passive serum therapy by GENOVESI, E. V, PETTEY, C. L, COLLINS, J. J

“…Previous studies have demonstrated that spleen cells from DBA/2 mice protected against challenge with a leukemogenic dose of Friend leukemia virus (FLV) by…”
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Susceptibility of Friend Virus Antigen-Modulated Erythroleukemic Cells to Lysis by T Lymphocytes from Mice with Dormant Friend Virus Infections by Genovesi, Eugene V, Marx, Preston A, Wheelock, E. Frederick

“…Spleen cells from DBA/2 mice with dormant Friend leukemia virus (FLV) infections or from mice immunized with x-irradiated FLC-745 erythroleukemic cells are not…”
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Corrigendum to “Respiratory syncytial virus fusion inhibitors. Part 4: Optimization for oral bioavailability” [Bioorg. Med. Chem. Lett. 17 (2007) 895–901] by Yu, Kuo-Long, Sin, Ny, Civiello, Rita L., Wang, X. Alan, Combrink, Keith D., Gulgeze, H. Belgin, Venables, Brian L., Kim Wright, J.J., Dalterio, Richard A., Zadjura, Lisa, Marino, Anthony, Dando, Sandra, D’Arienzo, Celia, Kadow, Kathleen F., Cianci, Christopher W., Li, Zhufang, Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Colonno, Richard J., Yang, Zheng, Krystal, Mark, Meanwell, Nicholas A.

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Orally active fusion inhibitor of respiratory syncytial virus by CIANCI, Christopher, YU, Kuo-Long, GENOVESI, Eugene V, VENABLES, Brian, GULGEZE, Hatice, TREHAN, Ashok, JAMES, Jennifer, LAMB, Lucinda, MEDINA, Ivette, ROACH, Julia, ZHENG YANG, ZADJURA, Lisa, COMBRINK, Keith, COLONNO, Richard, CLARK, Junius, MEANWELL, Nicholas, KRYSTAL, Mark, NY SIN, PEARCE, Bradley, WANG, Alan, CIVIELLO, Rita, VOSS, Stacey, GUANGXIANG LUO, KADOW, Kathy

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In vivo and in vitro effects of moderately virulent African swine fever virus on mitogenesis of pig lymphocytes by Knudsen, R C, Genovesi, E V

“…Six pigs were infected oro-nasally with a moderately virulent African swine fever (ASF) virus from the Dominican Republic (DR II). The effect of virus…”
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Susceptibility of inbred Syrian golden hamsters (Mesocricetus auratus) to lethal disease by lymphocytic choriomeningitis virus by Genovesi, E V, Peters, C J

“…An acutely lethal LCMV disease model has been established in the Syrian golden hamster (Mesocricetus auratus) in which lethality and disease are dependent upon…”
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Immunotherapy of murine leukemia. VII. Prevention of Friend leukemia virus-induced immunosuppression by passive serum therapy by Genovesi, E V, Livnat, D, Collins, J J

“…Previous studies have suggested that the passive therapy of Friend leukemia virus (FLV)-induced disease with chimpanzee anti-FLV serum operates by reducing the…”
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Immunotherapy of murine leukemia. V. Protection against Friend leukemia virus-induced immune complex glomerulonephritis by passive serum therapy by Sanfilippo, F, Genovesi, E V, Collins, J J

“…The development of immune complex glomerulonephritis in DBA/2 mice infected with Friend murine leukemia virus (F-MuLV) was compared with that in mice protected…”
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In vitro growth inhibition of murine leukemia cells by antibody specific for the major envelope glycoprotein (gp71) of Friend leukemia virus by Genovesi, E V, Collins, J J

“…An in vitro complement (C')-independent growth cytostasis model is described in which the replication of Friend leukemia virus (FLV)-induced erythroleukemia…”
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Immunotherapy of murine leukemia VI. Development of immunologic memory in mice protected against Friend leukemia virus-induced disease by passive serum therapy by Genovesi, E V, Livnat, D, Collins, J J

“…The resistance of DBA/2 mice to infection with a leukemogenic dose of Friend leukemia virus (FLV) as a result of the passive administration of chimpanzee…”
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Immunotherapy of murine leukemia. VIII. Efficacy of passive serum therapy of Friend leukemia virus-induced disease in immunocompromised mice by Genovesi, E V, Livnat, D, Collins, J J

“…Previous studies have demonstrated that the passive therapy of Friend murine leukemia virus (F-MuLV)-induced disease with chimpanzee anti-F-MuLV serum is…”
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Antigenic modulation of Friend virus erythroleukemic cells in vitro by serum from mice with dormant erythroleukemia by Genovesi, E V, Marx, P A, Wheelock, E F

“…Friend leukemia virus (FLV) erythroleukemic cells cultured in medium containing FLV-immune serum from dormant FLV-infected mice undergo modulation of FLV cell…”
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