Search Results - "Genova, Cecilia di"
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Studying longitudinal neutralising antibody levels against Equid herpesvirus 1 in experimentally infected horses using a novel pseudotype based assay
Published in Virus research (02-01-2024)“…•gB, gD, gH and gL glycoproteins are required and sufficient for EHV-1 PV cell entry.•EHV-1 specific antibodies are measurable in a pseudotype virus…”
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Genetic characterization of a new candidate hemagglutinin subtype of influenza A viruses
Published in Emerging microbes & infections (01-12-2023)“…Avian influenza viruses (AIV) have been classified on the basis of 16 subtypes of hemagglutinin (HA) and 9 subtypes of neuraminidase. Here we describe genomic…”
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Human seasonal coronavirus neutralization and COVID‐19 severity
Published in Journal of medical virology (01-10-2022)“…The virus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), responsible for the global coronavirus disease‐2019 (COVID‐19) pandemic, spread rapidly…”
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Coronavirus Pseudotypes for All Circulating Human Coronaviruses for Quantification of Cross-Neutralizing Antibody Responses
Published in Viruses (10-08-2021)“…The novel coronavirus SARS-CoV-2 is the seventh identified human coronavirus. Understanding the extent of pre-existing immunity induced by seropositivity to…”
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Production, Titration, Neutralisation, Storage and Lyophilisation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lentiviral Pseudotypes
Published in Bio-protocol (05-11-2021)“…This protocol details a rapid and reliable method for the production and titration of high-titre viral pseudotype particles with the SARS-CoV-2 spike protein…”
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Analysis of Antibody Neutralisation Activity against SARS-CoV-2 Variants and Seasonal Human Coronaviruses NL63, HKU1, and 229E Induced by Three Different COVID-19 Vaccine Platforms
Published in Vaccines (Basel) (27-12-2022)“…Coronaviruses infections, culminating in the recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic beginning in 2019, have highlighted…”
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Approaches to Pseudotype DNA and RNA Viruses of Veterinary Interest for Use as Tools in Cell Tropism and Immune Response Studies
Published 01-01-2022“…Pseudotype viruses (PVs) provide an alternative platform to wild type viruses since they mimic their receptor binding and entry processes and able to interact…”
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Dissertation -
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Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose
Published in Science (American Association for the Advancement of Science) (25-06-2021)“…SARS-CoV-2 vaccine rollout has coincided with the spread of variants of concern. We investigated if single dose vaccination, with or without prior infection,…”
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Extremely potent human monoclonal antibodies from COVID-19 convalescent patients
Published in Cell (01-04-2021)“…Human monoclonal antibodies are safe, preventive, and therapeutic tools that can be rapidly developed to help restore the massive health and economic…”
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Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) from the 2021/22 epizootic is highly duck adapted and poorly adapted to chickens
Published in Journal of general virology (01-05-2023)“…The 2021/2022 epizootic of high pathogenicity avian influenza (HPAIV) remains one of the largest ever in the UK, being caused by a clade 2.3.4.4b H5N1 HPAIV…”
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Generation of EHV‐1 pseudotype virus for cell tropism studies and virus‐neutralising assays
Published in Equine veterinary journal (01-09-2021)Get full text
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Use of Equine Herpesvirus 1 glycoprotein pseudotyped lentiviral particles for the development of serological tests and assessment of lyophilisation for transport and storage
Published in Access microbiology (18-05-2022)“…Equine herpesviruses (EHVs) are enveloped DNA viruses predominantly infecting members of the Equidae family. EHVs primarily cause respiratory disease, however…”
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Comparison of lentiviral and vesicular stomatitis virus core SARS-CoV-2 pseudotypes and generation of a stable cell line for use in antibody neutralisation assays
Published in Access microbiology (18-05-2022)“…Betacoronavirus SARS-CoV-2, the causative agent of COVID19, is a single stranded positive sense RNA virus. Since its emergence there has been great efforts to…”
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Generation of Equine Herpesvirus type 1 glycoprotein pseudotyped lentiviral particles for use as a tool for tropism and diagnostic studies
Published in Access microbiology (10-07-2020)“…Equine herpesviruses (EHVs) are enveloped DNA viruses infecting mainly members of the Equidae family and also members of other taxa. EHVs primarily causing…”
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Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response
Published in Cell reports methods (19-09-2022)“…Determining the protection an individual has to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern (VoCs) is crucial for future…”
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