Search Results - "Genoula, Melanie"

PD-1/PD-L1 Pathway Modulates Macrophage Susceptibility to Mycobacterium tuberculosis Specific CD8+ T cell Induced Death by Suarez, Guadalupe Verónica, Melucci Ganzarain, Claudia del Carmen, Vecchione, María Belén, Trifone, César Ariel, Marín Franco, José Luis, Genoula, Melanie, Moraña, Eduardo José, Balboa, Luciana, Quiroga, Maria Florencia

“…CD8 + T cells contribute to tuberculosis (TB) infection control by inducing death of infected macrophages. Mycobacterium tuberculosis ( Mtb ) infection is…”
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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis by Maio, Mariano, Barros, Joaquina, Joly, Marine, Vahlas, Zoi, Marín Franco, José Luis, Genoula, Melanie, Monard, Sarah C, Vecchione, María Belén, Fuentes, Federico, Gonzalez Polo, Virginia, Quiroga, María Florencia, Vermeulen, Mónica, Vu Manh, Thien-Phong, Argüello, Rafael J, Inwentarz, Sandra, Musella, Rosa, Ciallella, Lorena, González Montaner, Pablo, Palmero, Domingo, Lugo Villarino, Geanncarlo, Sasiain, María Del Carmen, Neyrolles, Olivier, Vérollet, Christel, Balboa, Luciana

“…During tuberculosis (TB), migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the…”
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Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation by Genoula, Melanie, Marín Franco, José Luis, Maio, Mariano, Dolotowicz, Belén, Ferreyra, Malena, Milillo, M Ayelén, Mascarau, Rémi, Moraña, Eduardo José, Palmero, Domingo, Matteo, Mario, Fuentes, Federico, López, Beatriz, Barrionuevo, Paula, Neyrolles, Olivier, Cougoule, Céline, Lugo-Villarino, Geanncarlo, Vérollet, Christel, Sasiain, María Del Carmen, Balboa, Luciana

“…The ability of Mycobacterium tuberculosis (Mtb) to persist inside host cells relies on metabolic adaptation, like the accumulation of lipid bodies (LBs) in the…”
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Brucella abortus RNA does not polarize macrophages to a particular profile but interferes with M1 polarization by Serafino, Agustina, Marin Franco, José L, Maio, Mariano, Trotta, Aldana, Genoula, Melanie, Castillo, Luis A, Birnberg Weiss, Federico, Pittaluga, José R, Balboa, Luciana, Barrionuevo, Paula, Milillo, M Ayelén

“…Monocytes and macrophages play a central role in chronic brucellosis. Brucella abortus (Ba) is an intracellular pathogen that survives inside these cells. On…”
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Fibroblast growth factor receptor-4 mediates activation of Nuclear Factor Erythroid 2-Related Factor-2 in gastric tumorigenesis by Soutto, Mohammed, Zhang, Xing, Bhat, Nadeem, Chen, Zheng, Zhu, Shoumin, Maacha, Selma, Genoula, Melanie, El-Gazzaz, Omar, Peng, Dunfa, Lu, Heng, McDonald, Oliver G., Chen, Xi Steven, Cao, Longlong, Xu, Zekuan, El-Rifai, Wael

“…Helicobacter pylori (H. pylori) is the leading risk factor for gastric carcinogenesis. Fibroblast growth factor receptor 4 (FGFR4) is a member of transmembrane…”
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Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4 + T Cell Responses by Milillo, M Ayelén, Trotta, Aldana, Serafino, Agustina, Marin Franco, José Luis, Marinho, Fábio V, Alcain, Julieta, Genoula, Melanie, Balboa, Luciana, Oliveira, Sergio Costa, Giambartolomei, Guillermo H, Barrionuevo, Paula

“…, the causative agent of brucellosis, displays many resources to evade T cell responses conducive to persist inside the host. Our laboratory has previously…”
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Anti-Neuroblastoma Properties of a Recombinant Sunflower Lectin by Pinedo, Marcela, Genoula, Melanie, Silveyra, María Ximena, De Oliveira Carvalho, André, Regente, Mariana, Del Río, Marianela, Ribeiro Soares, Júlia, Moreira Gomes, Valdirene, De La Canal, Laura

“…According to their sugar recognition specificity, plant lectins are proposed as bioactive proteins with potential in cancer treatment and diagnosis. Helja is a…”
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Abstract 1379 CDK1-SOX9 axis contributes to chemotherapy resistance in gastric cancer by Al-Mathkour, Marwah, Zhu, Shoumin, Genoula, Melanie, El-Rifai, Wael

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Su1184 CDK1-SOX9 AXIS CONTRIBUTES TO CHEMOTHERAPY RESISTANCE IN GASTRIC CANCER by AL-Mathkour, Marwah M., Zhu, Shoumin, Genoula, Melanie, El-Rifai, Wael

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333 H. PYLORI INFECTION INDUCES SOX9 THROUGH CAP-DEPENDENT TRANSLATION MEDIATED BY AURKA-EIF4E AXIS by Gomaa, Ahmed R., Maacha, Selma, Peng, Dunfa, Soutto, Mohammed, Genoula, Melanie, Bhat, Nadeem, Cao, Longlong, Zhu, Shoumin, McDonald, Oliver G., El-Rifai, Wael

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1290 FIBROBLAST GROWTH FACTOR RECEPTOR-4 PROMOTES ANTIOXIDANT RESPONSE VIA ACTIVATION OF NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR-2 IN GASTRIC CANCER by Soutto, Mohammed, Zhang, Xing, Bhat, Nadeem, Chen, Zheng, Zhu, Shoumin, Maacha, Selma, Genoula, Melanie, Gomaa, Ahmed R., Peng, Dunfa, Lu, Heng, El-Gazzaz, Omar, McDonald, Oliver G., Chen, Xi S., Cao, Longlong, Xu, Zekuan, El-Rifai, Wael

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SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation by Gomaa, Ahmed, Maacha, Selma, Peng, Dunfa, Soutto, Mohammed, Genoula, Melanie, Bhat, Nadeem, Cao, Longlong, Zhu, Shoumin, Castells, Antoni, Chen, Zhibin, Zaika, Alexander, McDonald, Oliver G., El-Rifai, Wael

“…Helicobacter pylori (H. pylori) infection is the main risk factor for gastric cancer. The SRY-Box Transcription Factor 9 (SOX9) serves as a marker of stomach…”
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Abstract 5872: CDK1-SOX9 axis contributes to chemotherapy resistance in gastric cancer by Al-Mathkour, Marwah M., Zhu, Shoumin, Genoula, Melanie, El-Rifai, Wael

“…Abstract Gastric carcinoma (GC) is the third most prevalent cause of cancer-related mortality worldwide, presenting a formidable challenge with the rise of…”
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SLAMF1 signaling induces Mycobacterium tuberculosis uptake leading to endolysosomal maturation in human macrophages by Barbero, Angela María, Trotta, Aldana, Genoula, Melanie, Pino, Rodrigo Emanuel Hernández Del, Estermann, Martín Andrés, Celano, Josefina, Fuentes, Federico, García, Verónica Edith, Balboa, Luciana, Barrionuevo, Paula, Pasquinelli, Virginia

“…Tuberculosis dates back to ancient times but it is not a problem of the past. Each year, millions of people die from tuberculosis. After inhalation of…”
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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis by Maio, Mariano, Barros, Joaquina, Joly, Marine, Vahlas, Zoi, Marín Franco, José Luis, Genoula, Melanie, Monard, Sarah C, Vecchione, María Belén, Fuentes, Federico, Gonzalez Polo, Virginia, Quiroga, María Florencia, Vermeulen, Mónica, Vu Manh, Thien-Phong, Argüello, Rafael J, Inwentarz, Sandra, Musella, Rosa, Ciallella, Lorena, González Montaner, Pablo, Palmero, Domingo, Lugo Villarino, Geanncarlo, Sasiain, María del Carmen, Neyrolles, Olivier, Vérollet, Christel, Balboa, Luciana

“…During tuberculosis (TB), migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the…”
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Host-Derived Lipids from Tuberculous Pleurisy Impair Macrophage Microbicidal-Associated Metabolic Activity by Marín Franco, José Luis, Genoula, Melanie, Corral, Dan, Duette, Gabriel, Ferreyra, Malena, Maio, Mariano, Dolotowicz, María Belén, Aparicio-Trejo, Omar Emiliano, Patiño-Martínez, Eduardo, Charton, Alison, Métais, Arnaud, Fuentes, Federico, Soldan, Vanessa, Moraña, Eduardo José, Palmero, Domingo, Ostrowski, Matías, Schierloh, Pablo, Sánchez-Torres, Carmen, Hernández-Pando, Rogelio, Pedraza-Chaverri, José, Rombouts, Yoann, Hudrisier, Denis, Layre, Emilie, Vérollet, Christel, Maridonneau-Parini, Isabelle, Neyrolles, Olivier, Sasiain, María Del Carmen, Lugo-Villarino, Geanncarlo, Balboa, Luciana

“…Mycobacterium tuberculosis (Mtb) regulates the macrophage metabolic state to thrive in the host, yet the responsible mechanisms remain elusive. Macrophage…”
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Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1[alpha] activation by Genoula, Melanie, Marín Franco, José Luis, Maio, Mariano, Dolotowicz, Belén, Ferreyra, Malena, Milillo, M. Ayelén, Mascarau, Rémi, Moraña, Eduardo José, Palmero, Domingo, Matteo, Mario, Fuentes, Federico, López, Beatriz, Barrionuevo, Paula, Neyrolles, Olivier, Cougoule, Céline, Lugo-Villarino, Geanncarlo, Vérollet, Christel, Sasiain, María del Carmen, Balboa, Luciana

“…The ability of Mycobacterium tuberculosis (Mtb) to persist inside host cells relies on metabolic adaptation, like the accumulation of lipid bodies (LBs) in the…”
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Abstract 638: FGFR4 mediates nuclear accumulation of NRF2 by binding to P62 in gastric cancer by Bhat, Nadeem S., Soutto, Mohammed, Zhang, Xing, Chen, Zheng, Zhu, Shoumin, Maacha, Selma, Genoula, Melanie, Peng, Dunfa, Lu, Heng, McDonald, Oliver G, Chen, Xi Steven, Cao, Longlong, Xu, Zekuan, El-Rifai, Wael

“…Abstract Background: Helicobacter pylori (H. pylori) is the major cause of gastric cancer. Fibroblast growth factor receptor 4 (FGFR4) is a member of the…”
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Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation by Genoula, Melanie, Marín Franco, José Luis, Dupont, Maeva, Kviatcovsky, Denise, Milillo, Ayelén, Schierloh, Pablo, Moraña, Eduardo Jose, Poggi, Susana, Palmero, Domingo, Mata-Espinosa, Dulce, González-Domínguez, Erika, León Contreras, Juan Carlos, Barrionuevo, Paula, Rearte, Bárbara, Córdoba Moreno, Marlina Olyissa, Fontanals, Adriana, Crotta Asis, Agostina, Gago, Gabriela, Cougoule, Céline, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Sánchez-Torres, Carmen, Hernández-Pando, Rogelio, Vérollet, Christel, Lugo-Villarino, Geanncarlo, Sasiain, María Del Carmen, Balboa, Luciana

“…The ability of (Mtb) to persist in its human host relies on numerous immune evasion strategies, such as the deregulation of the lipid metabolism leading to the…”
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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis by Maio, Mariano, Barros, Joaquina, Joly, Marine, Vahlas, Zoi, Marín Franco, José Luis, Genoula, Melanie, Monard, Sarah, Vecchione, María Belén, Fuentes, Federico, Gonzalez Polo, Virginia, Quiroga, María Florencia, Vermeulen, Mónica, Vu Manh, Thien-Phong, Argüello, Rafael J, Inwentarz, Sandra, Musella, Rosa, Ciallella, Lorena, González Montaner, Pablo, Palmero, Domingo, Lugo Villarino, Geanncarlo, Sasiain, María del Carmen, Neyrolles, Olivier, Vérollet, Christel, Balboa, Luciana

“…During tuberculosis (TB), migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the…”
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