Search Results - "Genoud, Christel"

Volume scanning electron microscopy for imaging biological ultrastructure by Titze, Benjamin, Genoud, Christel

“…Electron microscopy (EM) has been a key imaging method to investigate biological ultrastructure for over six decades. In recent years, novel volume EM…”
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Is EM dead? by Knott, Graham, Genoud, Christel

“…Since electron microscopy (EM) first appeared in the 1930s, it has held centre stage as the primary tool for the exploration of biological structure. Yet, with…”
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Complete loss of H3K9 methylation dissolves mouse heterochromatin organization by Montavon, Thomas, Shukeir, Nicholas, Erikson, Galina, Engist, Bettina, Onishi-Seebacher, Megumi, Ryan, Devon, Musa, Yaarub, Mittler, Gerhard, Meyer, Alexandra Graff, Genoud, Christel, Jenuwein, Thomas

“…Histone H3 lysine 9 (H3K9) methylation is a central epigenetic modification that defines heterochromatin from unicellular to multicellular organisms. In…”
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Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes by Shahmoradian, Sarah H., Lewis, Amanda J., Genoud, Christel, Hench, Jürgen, Moors, Tim E., Navarro, Paula P., Castaño-Díez, Daniel, Schweighauser, Gabriel, Graff-Meyer, Alexandra, Goldie, Kenneth N., Sütterlin, Rosmarie, Huisman, Evelien, Ingrassia, Angela, Gier, Yvonne de, Rozemuller, Annemieke J. M., Wang, Jing, Paepe, Anne De, Erny, Johannes, Staempfli, Andreas, Hoernschemeyer, Joerg, Großerüschkamp, Frederik, Niedieker, Daniel, El-Mashtoly, Samir F., Quadri, Marialuisa, Van IJcken, Wilfred F. J., Bonifati, Vincenzo, Gerwert, Klaus, Bohrmann, Bernd, Frank, Stephan, Britschgi, Markus, Stahlberg, Henning, Van de Berg, Wilma D. J., Lauer, Matthias E.

“…Parkinson’s disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological…”
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Learning-related feedforward inhibitory connectivity growth required for memory precision by Ruediger, Sarah, Vittori, Claudia, Bednarek, Ewa, Genoud, Christel, Strata, Piergiorgio, Sacchetti, Benedetto, Caroni, Pico

“…Memories made with precision Learning and memory tasks are associated with the addition of new synapses in the brain, but the function of this structural…”
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Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER by Heusermann, Wolf, Hean, Justin, Trojer, Dominic, Steib, Emmanuelle, von Bueren, Stefan, Graff-Meyer, Alexandra, Genoud, Christel, Martin, Katrin, Pizzato, Nicolas, Voshol, Johannes, Morrissey, David V, Andaloussi, Samir E L, Wood, Matthew J, Meisner-Kober, Nicole C

“…Exosomes are nanovesicles released by virtually all cells, which act as intercellular messengers by transfer of protein, lipid, and RNA cargo. Their…”
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Dense EM-based reconstruction of the interglomerular projectome in the zebrafish olfactory bulb by Wanner, Adrian A, Genoud, Christel, Masudi, Tafheem, Siksou, Léa, Friedrich, Rainer W

“…The authors used new 3D electron microscopy techniques and analyses to reconstruct virtually all neurons in the olfactory bulb of a zebrafish larva. The…”
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Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity by Pinheiro, Inês, Margueron, Raphaël, Shukeir, Nicholas, Eisold, Michael, Fritzsch, Christoph, Richter, Florian M., Mittler, Gerhard, Genoud, Christel, Goyama, Susumu, Kurokawa, Mineo, Son, Jinsook, Reinberg, Danny, Lachner, Monika, Jenuwein, Thomas

“…Heterochromatin serves important functions, protecting genome integrity and stabilizing gene expression programs. Although the Suv39h methyltransferases (KMTs)…”
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BMP signaling specifies the development of a large and fast CNS synapse by Xiao, Le, Michalski, Nicolas, Kronander, Elin, Gjoni, Enida, Genoud, Christel, Knott, Graham, Schneggenburger, Ralf

“…The calyx of Held synapse in the auditory brainstem is an unusually large and fast synapse. Using genome-wide screening and conditional deletion in mice, Xiao…”
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Hierarchical Microtubule Organization Controls Axon Caliber and Transport and Determines Synaptic Structure and Stability by Stephan, Raiko, Goellner, Bernd, Moreno, Eliza, Frank, C. Andrew, Hugenschmidt, Tabea, Genoud, Christel, Aberle, Hermann, Pielage, Jan

“…The dimensions of axons and synaptic terminals determine cell-intrinsic properties of neurons; however, the cellular mechanisms selectively controlling…”
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Correlated cryo-SEM and CryoNanoSIMS imaging of biological tissue by Meibom, Anders, Plane, Florent, Cheng, Tian, Grandjean, Gilles, Haldimann, Olivier, Escrig, Stephane, Jensen, Louise, Daraspe, Jean, Mucciolo, Antonio, De Bellis, Damien, Rädecker, Nils, Martin-Olmos, Cristina, Genoud, Christel, Comment, Arnaud

“…The development of nanoscale secondary ion mass spectrometry (NanoSIMS) has revolutionized the study of biological tissues by enabling, e.g., the visualization…”
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Neurofilament light chain plasma levels are associated with area of brain damage in experimental cerebral malaria by Wai, Chi Ho, Jin, Jessica, Cyrklaff, Marek, Genoud, Christel, Funaya, Charlotta, Sattler, Julia, Maceski, Aleksandra, Meier, Stephanie, Heiland, Sabine, Lanzer, Michael, Frischknecht, Friedrich, Kuhle, Jens, Bendszus, Martin, Hoffmann, Angelika

“…Neurofilament light chain (NfL), released during central nervous injury, has evolved as a powerful serum marker of disease severity in many neurological…”
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Plasticity of astrocytic coverage and glutamate transporter expression in adult mouse cortex by Genoud, Christel, Quairiaux, Charles, Steiner, Pascal, Hirling, Harald, Welker, Egbert, Knott, Graham W

“…Astrocytes play a major role in the removal of glutamate from the extracellular compartment. This clearance limits the glutamate receptor activation and…”
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Fast Homogeneous En Bloc Staining of Large Tissue Samples for Volume Electron Microscopy by Genoud, Christel, Titze, Benjamin, Graff-Meyer, Alexandra, Friedrich, Rainer W

“…Fixation and staining of large tissue samples are critical for the acquisition of volumetric electron microscopic image datasets and the subsequent…”
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Photoreceptor phagocytosis is mediated by phosphoinositide signaling by Mustafi, Debarshi, Kevany, Brian M., Genoud, Christel, Bai, Xiaodong, Palczewski, Krzysztof

“…Circadian oscillations in peripheral tissues, such as the retinal compartment of the eye, are critical to anticipating changing metabolic demands. Circadian…”
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Host-derived organic acids enable gut colonization of the honey bee symbiont Snodgrassella alvi by Quinn, Andrew, El Chazli, Yassine, Escrig, Stéphane, Daraspe, Jean, Neuschwander, Nicolas, McNally, Aoife, Genoud, Christel, Meibom, Anders, Engel, Philipp

“…Diverse bacteria can colonize the animal gut using dietary nutrients or by engaging in microbial crossfeeding interactions. Less is known about the role of…”
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SBEMimage : Versatile Acquisition Control Software for Serial Block-Face Electron Microscopy by Titze, Benjamin, Genoud, Christel, Friedrich, Rainer W

“…We present , an open-source Python-based application to operate serial block-face electron microscopy (SBEM) systems. is designed for complex, challenging…”
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Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis by Toullec, Gaëlle, Rädecker, Nils, Pogoreutz, Claudia, Banc-Prandi, Guilhem, Escrig, Stéphane, Genoud, Christel, Olmos, Cristina Martin, Spangenberg, Jorge, Meibom, Anders

“…Global warming is causing large-scale disruption of cnidarian-Symbiodiniaceae symbioses fundamental to major marine ecosystems, such as coral reefs. However,…”
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Ume6-dependent pathways of morphogenesis and biofilm formation in Candida auris by Louvet, Marine, Li, Jizhou, Brandalise, Danielle, Bachmann, Daniel, Sala de Oyanguren, Francisco, Labes, Danny, Jacquier, Nicolas, Genoud, Christel, Mucciolo, Antonio, Coste, Alix T, Sanglard, Dominique, Lamoth, Frederic

“…is a yeast pathogen causing nosocomial outbreaks of candidemia. Its ability to adhere to inert surfaces and to be transmitted from one patient to another via…”
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3-dimensional electron microscopic imaging of the zebrafish olfactory bulb and dense reconstruction of neurons by Wanner, Adrian A., Genoud, Christel, Friedrich, Rainer W.

“…Large-scale reconstructions of neuronal populations are critical for structural analyses of neuronal cell types and circuits. Dense reconstructions of neurons…”
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