Search Results - "Genno, Shuji"

Inhibition of yes-associated protein suppresses migration, invasion, and metastasis in non-small cell lung cancer in vitro and in vivo by Takeda, Tomoya, Tsubaki, Masanobu, Genno, Shuji, Matsuda, Takuya, Yamamoto, Yuuta, Kimura, Akihiro, Shimizu, Nao, Nishida, Shozo

“…Non-small cell lung cancer (NSCLC) is a highly aggressive cancer with one of the most prevalent malignant tumors. Metastasis in NSCLC is the major cause of…”
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AT9283 exhibits antiproliferative effect on tyrosine kinase inhibitor‑sensitive and ‑resistant chronic myeloid leukemia cells by inhibition of Aurora A and Aurora B by Takeda, Tomoya, Tsubaki, Masanobu, Genno, Shuji, Nemoto, Chisato, Onishi, Yasuka, Yamamoto, Yuuta, Imano, Motohiro, Satou, Takao, Nishida, Shozo

“…Imatinib is the gold standard in the conventional treatment of chronic myeloid leukemia (CML). However, some patients become resistant to imatinib therapy. To…”
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RANK/RANKL axis promotes migration, invasion, and metastasis of osteosarcoma via activating NF-κB pathway by Takeda, Tomoya, Tsubaki, Masanobu, Genno, Shuji, Tomita, Kana, Nishida, Shozo

“…Osteosarcoma (OS) is one of the most prevalent primary bone tumors with a high degree of metastasis and poor prognosis. Epithelial-to-mesenchymal transition…”
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HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression by Takeda, Tomoya, Tsubaki, Masanobu, Genno, Shuji, Tokunaga, Kenta, Tanaka, Remi, Nishida, Shozo

“…Triple-negative breast cancer (TNBC), a highly metastatic subtype of breast cancer, and it has the worst prognosis among all subtypes of breast cancer…”
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Sorafenib treatment of metastatic melanoma with c‑Kit aberration reduces tumor growth and promotes survival by Takeda, Tomoya, Tsubaki, Masanobu, Kato, Natsuki, Genno, Shuji, Ichimura, Eri, Enomoto, Aya, Imano, Motohiro, Satou, Takao, Nishida, Shozo

“…Melanomas are highly malignant tumors that readily metastasize and have poor prognosis. Targeted therapy is a cornerstone of treatment for patients with…”
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