Search Results - "Genin, M"

Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment by Huang, Guoyou, Li, Fei, Zhao, Xin, Ma, Yufei, Li, Yuhui, Lin, Min, Jin, Guorui, Lu, Tian Jian, Genin, Guy M, Xu, Feng

“…The cell microenvironment has emerged as a key determinant of cell behavior and function in development, physiology, and pathophysiology. The extracellular…”
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Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D by Jiang, Shumeng, Lyu, Cheng, Zhao, Peng, Li, Wenjing, Kong, Wenyu, Huang, Chenyu, Genin, Guy M., Du, Yanan

“…Despite the wide applications, systematic mechanobiological investigation of 3D porous scaffolds has yet to be performed due to the lack of methodologies for…”
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Programmable and robust static topological solitons in mechanical metamaterials by Zhang, Yafei, Li, Bo, Zheng, Q. S., Genin, Guy M., Chen, C. Q.

“…Solitary, persistent wave packets called solitons hold potential to transfer information and energy across a wide range of spatial and temporal scales in…”
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Physical Activity, Inactivity, and Sedentary Behaviors: Definitions and Implications in Occupational Health by Thivel, David, Tremblay, Angelo, Genin, Pauline M, Panahi, Shirin, Rivière, Daniel, Duclos, Martine

“…Based on the increasing evidence linking excessive sedentary behaviors and adverse health outcomes, public health strategies have been developed and constantly…”
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Spatiotemporally Controlled Photoresponsive Hydrogels: Design and Predictive Modeling from Processing through Application by Zhu, Hongyuan, Yang, Haiqian, Ma, Yufei, Lu, Tian Jian, Xu, Feng, Genin, Guy M., Lin, Min

“…Photoresponsive hydrogels (PRHs) are soft materials whose mechanical and chemical properties can be tuned spatially and temporally with relative ease. Both…”
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Mineral distributions at the developing tendon enthesis by Schwartz, Andrea G, Pasteris, Jill D, Genin, Guy M, Daulton, Tyrone L, Thomopoulos, Stavros

“…Tendon attaches to bone across a functionally graded interface, "the enthesis". A gradient of mineral content is believed to play an important role for…”
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Functional Grading of Mineral and Collagen in the Attachment of Tendon to Bone by Genin, Guy M., Kent, Alistair, Birman, Victor, Wopenka, Brigitte, Pasteris, Jill D., Marquez, Pablo J., Thomopoulos, Stavros

“…Attachment of dissimilar materials is a major challenge because high levels of localized stress may develop at their interfaces. An effective biologic solution…”
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Measurement of mechanical tractions exerted by cells in three-dimensional matrices by Chen, Christopher S, Legant, Wesley R, Miller, Jordan S, Blakely, Brandon L, Cohen, Daniel M, Genin, Guy M

“…Quantitative measurements of cell-generated forces have heretofore required that cells be cultured on two-dimensional substrates. We describe a technique to…”
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Mechanics-driven nuclear localization of YAP can be reversed by N-cadherin ligation in mesenchymal stem cells by Zhang, Cheng, Zhu, Hongyuan, Ren, Xinru, Gao, Bin, Cheng, Bo, Liu, Shaobao, Sha, Baoyong, Li, Zhaoqing, Zhang, Zheng, Lv, Yi, Wang, Haohua, Guo, Hui, Lu, Tian Jian, Xu, Feng, Genin, Guy M., Lin, Min

“…Mesenchymal stem cells adopt differentiation pathways based upon cumulative effects of mechanosensing. A cell’s mechanical microenvironment changes…”
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Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation by Zhang, Zheng, Sha, Baoyong, Zhao, Lingzhu, Zhang, Huan, Feng, Jinteng, Zhang, Cheng, Sun, Lin, Luo, Meiqing, Gao, Bin, Guo, Hui, Wang, Zheng, Xu, Feng, Lu, Tian Jian, Genin, Guy M., Lin, Min

“…During mesenchymal development, the sources of mechanical forces transduced by cells transition over time from predominantly cell-cell interactions to…”
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Energy dissipation in mammalian collagen fibrils: Cyclic strain-induced damping, toughening, and strengthening by Liu, Julia, Das, Debashish, Yang, Fan, Schwartz, Andrea G., Genin, Guy M., Thomopoulos, Stavros, Chasiotis, Ioannis

“…[Display omitted] As the fundamental structural protein in mammals, collagen transmits cyclic forces that are necessary for the mechanical function of tissues,…”
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Tailoring of arteriovenous graft-to-vein anastomosis angle to attenuate pathological flow fields by Williams, Dillon, Leuthardt, Eric C., Genin, Guy M., Zayed, Mohamed

“…Arteriovenous grafts are routinely placed to facilitate hemodialysis in patients with end stage renal disease. These grafts are conduits between higher…”
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The brain as a structure: A model of how fluid–structure interactions stiffen brain tissue after injury by Feng, Yuan, Chen, Yu, Yao, Yifei, Li, Xiaowei, Zhang, Aili, Genin, Guy M.

“…•A fluid–structure interaction model was constructed to explain the tissue stiffening effect of brain tissue after injury.•Radius, flow speed, and connectivity…”
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Reduced graphene oxide functionalized nanofibrous silk fibroin matrices for engineering excitable tissues by Zhao, Guoxu, Qing, Huaibin, Huang, Guoyou, Genin, Guy M., Lu, Tian Jian, Luo, Zhengtang, Xu, Feng, Zhang, Xiaohui

“…Tissue engineering has provided an alternative strategy for the regeneration of functional tissues for drug screening and disease intervention. The central…”
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The Arabidopsis trichome is an active mechanosensory switch by Zhou, Li Hong, Liu, Shao Bao, Wang, Peng Fei, Lu, Tian Jian, Xu, Feng, Genin, Guy M., Pickard, Barbara G.

“…Trichomes (‘hair cells’) on Arabidopsis thaliana stem and leaf surfaces provide a range of benefits arising from their shape and disposition. These include…”
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Micro-mechanical properties of the tendon-to-bone attachment by Deymier, Alix C., An, Yiran, Boyle, John J., Schwartz, Andrea G., Birman, Victor, Genin, Guy M., Thomopoulos, Stavros, Barber, Asa H.

“…[Display omitted] The tendon-to-bone attachment (enthesis) is a complex hierarchical tissue that connects stiff bone to compliant tendon. The attachment site…”
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Transmission, attenuation and reflection of shear waves in the human brain by Clayton, Erik H., Genin, Guy M., Bayly, Philip V.

“…Traumatic brain injuries (TBIs) are caused by acceleration of the skull or exposure to explosive blast, but the processes by which mechanical loads lead to…”
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Flexible Miniaturized Sensor Technologies for Long-Term Physiological Monitoring by He, Rongyan, Liu, Hao, Niu, Yan, Zhang, Huiqing, Genin, Guy M., Xu, Feng

“…Physiological monitoring can provide detailed information about health conditions, and therefore presents great potentials for personalized healthcare…”
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Indication for molecular testing by multiplex ligation‐dependent probe amplification in parkinsonism by Mutez, E., Swiderski, M., Devos, D., Moreau, C., Baille, G., Degardin, A., Ryckewaert, G., Carriere, N., Kreisler, A., Simonin, C., Rouaix, N., Tir, M., Krystkowiak, P., Ramdane, N., Génin, M., Sablonnière, B., Defebvre, L., Huin, V.

“…Background and purpose The monogenic forms of Parkinson's disease represent <10% of familial cases and a still lower frequency of sporadic cases. However,…”
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Phase separation in biological membranes: integration of theory and experiment by Elson, Elliot L, Fried, Eliot, Dolbow, John E, Genin, Guy M

“…Lipid bilayer model membranes that contain a single lipid species can undergo transitions between ordered and disordered phases, and membranes that contain a…”
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