Search Results - "Genetics (Austin)"
-
1
The Gene Ontology knowledgebase in 2023
Published in Genetics (Austin) (04-05-2023)“…Abstract The Gene Ontology (GO) knowledgebase (http://geneontology.org) is a comprehensive resource concerning the functions of genes and gene products…”
Get full text
Journal Article -
2
R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
Published in Genetics (Austin) (01-02-2019)“…R/qtl2 is an interactive software environment for mapping quantitative trait loci (QTL) in experimental populations. The R/qtl2 software expands the scope of…”
Get full text
Journal Article -
3
Efficient ancestry and mutation simulation with msprime 1.0
Published in Genetics (Austin) (03-03-2022)“…Abstract Stochastic simulation is a key tool in population genetics, since the models involved are often analytically intractable and simulation is usually the…”
Get full text
Journal Article -
4
Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans
Published in Genetics (Austin) (01-11-2018)“…CRISPR-based genome editing using ribonucleoprotein complexes and synthetic single-stranded oligodeoxynucleotide (ssODN) donors can be highly effective…”
Get full text
Journal Article -
5
The Natural Biotic Environment of Caenorhabditis elegans
Published in Genetics (Austin) (01-05-2017)“…Organisms evolve in response to their natural environment. Consideration of natural ecological parameters are thus of key importance for our understanding of…”
Get full text
Journal Article -
6
Drosophila as a Genetic Model for Hematopoiesis
Published in Genetics (Austin) (01-02-2019)“…In this FlyBook chapter, we present a survey of the current literature on the development of the hematopoietic system in The blood system consists entirely of…”
Get full text
Journal Article -
7
Chromosome Duplication in Saccharomyces cerevisiae
Published in Genetics (Austin) (01-07-2016)“…The accurate and complete replication of genomic DNA is essential for all life. In eukaryotic cells, the assembly of the multi-enzyme replisomes that perform…”
Get full text
Journal Article -
8
Identifying causal variants at loci with multiple signals of association
Published in Genetics (Austin) (01-10-2014)“…Although genome-wide association studies have successfully identified thousands of risk loci for complex traits, only a handful of the biologically causal…”
Get full text
Journal Article -
9
Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
Published in Genetics (Austin) (01-08-2015)“…Using genome-wide genotypes, we characterized the genetic structure of 103,006 participants in the Kaiser Permanente Northern California multi-ethnic Genetic…”
Get full text
Journal Article -
10
FlyBase: updates to the Drosophila genes and genomes database
Published in Genetics (Austin) (07-05-2024)“…FlyBase (flybase.org) is a model organism database and knowledge base about Drosophila melanogaster, commonly known as the fruit fly. Researchers from around…”
Get full text
Journal Article -
11
The ModERN Resource: Genome-Wide Binding Profiles for Hundreds of Drosophila and Caenorhabditis elegans Transcription Factors
Published in Genetics (Austin) (01-03-2018)“…To develop a catalog of regulatory sites in two major model organisms, and , the modERN (model organism Encyclopedia of Regulatory Networks) consortium has…”
Get full text
Journal Article -
12
Genetics on the Fly: A Primer on the Drosophila Model System
Published in Genetics (Austin) (01-11-2015)“…Fruit flies of the genus Drosophila have been an attractive and effective genetic model organism since Thomas Hunt Morgan and colleagues made seminal…”
Get full text
Journal Article -
13
Phylogeny of the Genus Drosophila
Published in Genetics (Austin) (01-05-2018)“…Understanding phylogenetic relationships among taxa is key to designing and implementing comparative analyses. The genus , which contains over 1600 species, is…”
Get full text
Journal Article -
14
Starvation Responses Throughout the Caenorhabditis elegans Life Cycle
Published in Genetics (Austin) (01-12-2020)“…Abstract Caenorhabditis elegans survives on ephemeral food sources in the wild, and the species has a variety of adaptive responses to starvation. These…”
Get full text
Journal Article -
15
Advances in Engineering the Fly Genome with the CRISPR-Cas System
Published in Genetics (Austin) (01-01-2018)“…has long been a premier model for the development and application of cutting-edge genetic approaches. The CRISPR-Cas system now adds the ability to manipulate…”
Get full text
Journal Article -
16
Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 Sites in Caenorhabditis elegans
Published in Genetics (Austin) (01-12-2014)“…Homology-directed repair (HDR) of double-strand DNA breaks is a promising method for genome editing, but is thought to be less efficient than error-prone…”
Get full text
Journal Article -
17
An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System
Published in Genetics (Austin) (01-10-2015)“…The fission yeast Schizosaccharomyces pombe is an important model organism for the study of eukaryotic molecular and cellular biology. Studies of S. pombe,…”
Get full text
Journal Article -
18
Life-History Evolution and the Genetics of Fitness Components in Drosophila melanogaster
Published in Genetics (Austin) (01-01-2020)“…Abstract Life-history traits or “fitness components”—such as age and size at maturity, fecundity and fertility, age-specific rates of survival, and life…”
Get full text
Journal Article -
19
Chemosensory signal transduction in Caenorhabditis elegans
Published in Genetics (Austin) (31-03-2021)“…Abstract Chemosensory neurons translate perception of external chemical cues, including odorants, tastants, and pheromones, into information that drives…”
Get full text
Journal Article -
20
Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples
Published in Genetics (Austin) (01-05-2017)“…The distribution of fitness effects (DFE) has considerable importance in population genetics. To date, estimates of the DFE come from studies using a small…”
Get full text
Journal Article