Search Results - "Genescá, Joan"

Effects of an intensive lifestyle intervention program on portal hypertension in patients with cirrhosis and obesity: The SportDiet study by Berzigotti, Annalisa, Albillos, Agustín, Villanueva, Candid, Genescá, Joan, Ardevol, Alba, Augustín, Salvador, Calleja, Jose Luis, Bañares, Rafael, García‐Pagán, Juan Carlos, Mesonero, Francisco, Bosch, Jaime

“…Obesity increases the risk of clinical decompensation in cirrhosis, possibly by increasing portal pressure. Whether weight reduction can be safely achieved…”
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Synergic effect of atorvastatin and ambrisentan on sinusoidal and hemodynamic alterations in a rat model of NASH by Bravo, Miren, Raurell, Imma, Barberá, Aurora, Hide, Diana, Gil, Mar, Estrella, Federico, Salcedo, María Teresa, Augustin, Salvador, Genescà, Joan, Martell, María

“…In non-alcoholic steatohepatitis (NASH), decreased nitric oxide and increased endothelin-1 (ET-1, also known as EDN1) released by sinusoidal endothelial cells…”
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Impact of anticoagulation on upper‐gastrointestinal bleeding in cirrhosis. A retrospective multicenter study by Cerini, Federica, Gonzalez, Javier Martínez, Torres, Ferran, Puente, Ángela, Casas, Meritxell, Vinaixa, Carmen, Berenguer, Marina, Ardevol, Alba, Augustin, Salvador, Llop, Elba, Senosiaín, Maria, Villanueva, Càndid, de la Peña, Joaquin, Bañares, Rafael, Genescá, Joan, Sopeña, Júlia, Albillos, Agustín, Bosch, Jaume, Hernández‐Gea, Virginia, Garcia‐Pagán, Juan Carlos

“…Recent studies have shown that liver cirrhosis (LC) behaves as an acquired hypercoagulable state with increased thrombotic risk. This is why anticoagulation…”
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Reply to: “Evaluating the role of transient elastography post chronic hepatitis C treatment to predict hepatocellular carcinoma” by Genescà, Joan

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Reply to: “Hepatocellular carcinoma surveillance after hepatitis C virus eradication: Is liver stiffness measurement more useful than laboratory fibrosis markers?” and “External validation of noninvasive predictors of hepatocellular carcinoma in patients with HCV advanced chronic liver disease after oral antivirals” by Genescà, Joan

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Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF by Moreau, Richard, Clària, Joan, Aguilar, Ferran, Fenaille, François, Lozano, Juan José, Junot, Christophe, Colsch, Benoit, Caraceni, Paolo, Trebicka, Jonel, Pavesi, Marco, Alessandria, Carlo, Nevens, Frederik, Saliba, Faouzi, Welzel, Tania M., Albillos, Agustin, Gustot, Thierry, Fernández, Javier, Moreno, Christophe, Baldassarre, Maurizio, Zaccherini, Giacomo, Piano, Salvatore, Montagnese, Sara, Vargas, Victor, Genescà, Joan, Solà, Elsa, Bernal, William, Butin, Noémie, Hautbergue, Thaïs, Cholet, Sophie, Castelli, Florence, Jansen, Christian, Steib, Christian, Campion, Daniela, Mookerjee, Raj, Rodríguez-Gandía, Miguel, Soriano, German, Durand, François, Benten, Daniel, Bañares, Rafael, Stauber, Rudolf E., Gronbaek, Henning, Coenraad, Minneke J., Ginès, Pere, Gerbes, Alexander, Jalan, Rajiv, Bernardi, Mauro, Arroyo, Vicente, Angeli, Paolo

“…Acute-on-chronic liver failure (ACLF), which develops in patients with cirrhosis, is characterized by intense systemic inflammation and organ failure(s)…”
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Preemptive‐TIPS Improves Outcome in High‐Risk Variceal Bleeding: An Observational Study by Hernández‐Gea, Virginia, Procopet, Bogdan, Giráldez, Álvaro, Amitrano, Lucio, Villanueva, Candid, Thabut, Dominique, Ibañez‐Samaniego, Luis, Silva‐Junior, Gilberto, Martinez, Javier, Genescà, Joan, Bureau, Christophe, Trebicka, Jonel, Llop, Elba, Laleman, Wim, Palazon, Jose Maria, Castellote, Jose, Rodrigues, Susana, Gluud, Lise L., Noronha Ferreira, Carlos, Barcelo, Rafael, Cañete, Nuria, Rodríguez, Manuel, Ferlitsch, Arnulf, Mundi, Jose Luis, Gronbaek, Henning, Hernández‐Guerra, Manuel, Sassatelli, Romano, Dell’Era, Alessandra, Senzolo, Marco, Abraldes, Juan G., Romero‐Gómez, Manuel, Zipprich, Alexander, Casas, Meritxell, Masnou, Helena, Primignani, Massimo, Krag, Aleksander, Nevens, Frederik, Calleja, Jose Luis, Jansen, Christian, Robic, Marie Angèle, Conejo, Irene, Catalina, Maria‐Vega, Albillos, Agustin, Rudler, Marika, Alvarado, Edilmar, Guardascione, Maria Anna, Tantau, Marcel, Bosch, Jaime, Torres, Ferran, Garcia‐Pagán, Juan Carlos

“…Patients admitted with acute variceal bleeding (AVB) and Child‐Pugh C score (CP‐C) or Child‐Pugh B plus active bleeding at endoscopy (CP‐B+AB) are at high risk…”
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Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis by García‐Lezana, Teresa, Raurell, Imma, Bravo, Miren, Torres‐Arauz, Manuel, Salcedo, María Teresa, Santiago, Alba, Schoenenberger, Andreu, Manichanh, Chaysavanh, Genescà, Joan, Martell, María, Augustin, Salvador

“…Portal hypertension (PH) drives most of the clinical complications in chronic liver diseases. However, its progression in nonalcoholic steatohepatitis (NASH)…”
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High mortality rates for SARS-CoV-2 infection in patients with pre-existing chronic liver disease and cirrhosis: Preliminary results from an international registry by Moon, Andrew M., Webb, Gwilym J., Aloman, Costica, Armstrong, Matthew J., Cargill, Tamsin, Dhanasekaran, Renumathy, Genescà, Joan, Gill, Upkar S., James, Theodore W., Jones, Patricia D., Marshall, Aileen, Mells, George, Perumalswami, Ponni V., Qi, Xiaolong, Su, Feng, Ufere, Nneka N., Barnes, Eleanor, Barritt, A. Sidney, Marjot, Thomas

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Total area of spontaneous portosystemic shunts independently predicts hepatic encephalopathy and mortality in liver cirrhosis by Praktiknjo, Michael, Simón-Talero, Macarena, Römer, Julia, Roccarina, Davide, Martínez, Javier, Lampichler, Katharina, Baiges, Anna, Low, Gavin, Llop, Elba, Maurer, Martin H., Zipprich, Alexander, Triolo, Michela, Maleux, Geert, Fialla, Annette Dam, Dam, Claus, Vidal-González, Judit, Majumdar, Avik, Picón, Carmen, Toth, Daniel, Darnell, Anna, Abraldes, Juan G., López, Marta, Jansen, Christian, Chang, Johannes, Schierwagen, Robert, Uschner, Frank, Kukuk, Guido, Meyer, Carsten, Thomas, Daniel, Wolter, Karsten, Strassburg, Christian P., Laleman, Wim, La Mura, Vincenzo, Ripoll, Cristina, Berzigotti, Annalisa, Calleja, José Luis, Tandon, Puneeta, Hernandez-Gea, Virginia, Reiberger, Thomas, Albillos, Agustín, Tsochatzis, Emmanuel A., Krag, Aleksander, Genescà, Joan, Trebicka, Jonel, Quiroga, Sergi, Yu, Dominic, Téllez, Luis, Mandorfer, Mattias, Garcia-Pagan, Juan Carlos, Berbel, Claudia, Ferrusquia, José, Ble, Michel, Garcia-Criado, Mari Angeles, Belmonte, Ernest, Ney, Michael, Margini, Cristina, Casu, Stefania, Murgia, Giuseppe, Ludwig, Christiane, Stangl, Franz

“…Spontaneous portosystemic shunts (SPSS) frequently develop in liver cirrhosis. Recent data suggested that the presence of a single large SPSS is associated…”
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Congenital Extrahepatic Portosystemic Shunts (Abernethy Malformation): An International Observational Study by Baiges, Anna, Turon, Fanny, Simón‐Talero, Macarena, Tasayco, Stephanie, Bueno, Javier, Zekrini, Kamal, Plessier, Aurélie, Franchi‐Abella, Stéphanie, Guerin, Florent, Mukund, Amar, Eapen, C.E., Goel, Ashish, Shyamkumar, Nidugala Keshava, Coenen, Sandra, Gottardi, Andrea, Majumdar, Avik, Onali, Simona, Shukla, Akash, Carrilho, Flair José, Nacif, Lucas, Primignani, Massimo, Tosetti, Giulia, Mura, Vicenzo, Nevens, Frederik, Witters, Peter, Tripathi, Dhiraj, Tellez, Luis, Martínez, Javier, Álvarez‐Navascués, Carmen, Fraile López, Miguel López, Procopet, Bogdan, Piscaglia, Fabio, Koning, Barbara, Llop, Elba, Romero‐Cristobal, Mario, Tjwa, Eric, Monescillo‐Francia, Alberto, Senzolo, Marco, Perez‐LaFuente, Mercedes, Segarra, Antonio, Sarin, Shiv Kumar, Hernández‐Gea, Virginia, Patch, David, Laleman, Wim, Hartog, Hermien, Valla, Dominique, Genescà, Joan, García‐Pagán, Juan Carlos

“…Congenital extrahepatic portosystemic shunt (CEPS) or Abernethy malformation is a rare condition in which splanchnic venous blood bypasses the liver draining…”
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Non-invasive prediction of liver-related events in patients with HCV-associated compensated advanced chronic liver disease after oral antivirals by Pons, Mònica, Rodríguez-Tajes, Sergio, Esteban, Juan Ignacio, Mariño, Zoe, Vargas, Víctor, Lens, Sabela, Buti, Maria, Augustin, Salvador, Forns, Xavier, Mínguez, Beatriz, Genescà, Joan

“…[Display omitted] •Liver stiffness improves after antiviral therapy in most patients.•Hepatocellular carcinoma can still occur after antiviral therapy in…”
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Noninvasive Diagnosis of Portal Hypertension in Patients With Compensated Advanced Chronic Liver Disease by Pons, Monica, Augustin, Salvador, Scheiner, Bernhard, Guillaume, Maeva, Rosselli, Matteo, Rodrigues, Susana G, Stefanescu, Horia, Ma, Mang M, Mandorfer, Mattias, Mergeay-Fabre, Mayka, Procopet, Bogdan, Schwabl, Philipp, Ferlitsch, Arnulf, Semmler, Georg, Berzigotti, Annalisa, Tsochatzis, Emmanuel, Bureau, Christophe, Reiberger, Thomas, Bosch, Jaime, Abraldes, Juan G, Genescà, Joan

“…We aimed to explore the prevalence of portal hypertension in the most common etiologies of patients with compensated advanced chronic liver disease (cACLD) and…”
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Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: The “Anticipate” study by Abraldes, Juan G., Bureau, Christophe, Stefanescu, Horia, Augustin, Salvador, Ney, Michael, Blasco, Hélène, Procopet, Bogdan, Bosch, Jaime, Genesca, Joan, Berzigotti, Annalisa

“…In patients with compensated advanced chronic liver disease (cACLD), the presence of clinically significant portal hypertension (CSPH) and varices needing…”
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β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial by Villanueva, Càndid, Albillos, Agustín, Genescà, Joan, Garcia-Pagan, Joan C, Calleja, José L, Aracil, Carles, Bañares, Rafael, Morillas, Rosa M, Poca, María, Peñas, Beatriz, Augustin, Salvador, Abraldes, Juan G, Alvarado, Edilmar, Torres, Ferran, Bosch, Jaume

“…Clinical decompensation of cirrhosis is associated with poor prognosis. Clinically significant portal hypertension (CSPH), defined by a hepatic venous pressure…”
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Spontaneous portosystemic shunts in liver cirrhosis: new approaches to an old problem by Vidal-González, Judit, Quiroga, Sergi, Simón-Talero, Macarena, Genescà, Joan

“…Portal hypertension is the main consequence of liver cirrhosis, leading to severe complications such as variceal hemorrhage, ascites or hepatic encephalopathy…”
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Noninvasive Assessment of Portal Hypertension by Bañares, Juan, Aceituno, Laia, Pons, Mònica, Genescà, Joan

“…The progressive use of noninvasive tests (NITs) has changed the way hepatologists diagnose and manage patients with chronic liver disease, mainly because of…”
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Do we need to re-define the Baveno VI elastography criteria for compensated advanced chronic liver disease (cACLD)? by Genescà, Joan, Abraldes, Juan G., Bosch, Jaime

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Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease: A prospective study by Augustin, Salvador, Millán, Laura, González, Antonio, Martell, María, Gelabert, Arántzazu, Segarra, Antoni, Serres, Xavier, Esteban, Rafael, Genescà, Joan

“…Background & Aims Detecting portal hypertension (PH) before the development of varices is important for prognosis and for designing interventional studies…”
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A MELD-Based Model to Determine Risk of Mortality Among Patients With Acute Variceal Bleeding by Reverter, Enric, Tandon, Puneeta, Augustin, Salvador, Turon, Fanny, Casu, Stefania, Bastiampillai, Ravin, Keough, Adam, Llop, Elba, González, Antonio, Seijo, Susana, Berzigotti, Annalisa, Ma, Mang, Genescà, Joan, Bosch, Jaume, García–Pagán, Joan Carles, Abraldes, Juan G

“…Background & Aims Patients with cirrhosis with acute variceal bleeding (AVB) have high mortality rates (15%–20%). Previously described models are seldom used…”
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