Search Results - "Genes"
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1
Transcription Factors Associated with Abiotic and Biotic Stress Tolerance and Their Potential for Crops Improvement
Published in Genes (30-09-2019)“…In field conditions, crops are adversely affected by a wide range of abiotic stresses including drought, cold, salt, and heat, as well as biotic stresses…”
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2
A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma
Published in Genes (10-05-2022)“…Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell carcinoma, which is characterized by metabolic reprogramming. Cuproptosis,…”
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3
Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae
Published in Genes (15-07-2020)“…Ergosterol is an essential component of fungal cell membranes that determines the fluidity, permeability and activity of membrane-associated proteins…”
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4
Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations
Published in Genes (26-07-2020)“…Being the most common musculoskeletal progressive condition, osteoarthritis is an interesting target for research. It is estimated that the prevalence of knee…”
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5
Eukaryotic 5-methylcytosine (m⁵C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease
Published in Genes (30-01-2019)“…5-methylcytosine (m⁵C) is an abundant RNA modification that's presence is reported in a wide variety of RNA species, including cytoplasmic and mitochondrial…”
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6
Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability
Published in Genes (15-05-2020)“…Histone deacetylases (HDACs) are evolutionary conserved enzymes which operate by removing acetyl groups from histones and other protein regulatory factors,…”
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7
Machine Learning and Integrative Analysis of Biomedical Big Data
Published in Genes (28-01-2019)“…Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome,…”
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8
Disease Resistance Mechanisms in Plants
Published in Genes (04-07-2018)“…Plants have developed a complex defense system against diverse pests and pathogens. Once pathogens overcome mechanical barriers to infection, plant receptors…”
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9
DNA Methylation Reprogramming during Mammalian Development
Published in Genes (29-03-2019)“…DNA methylation (5-methylcytosine, 5mC) is a major form of DNA modification in the mammalian genome that plays critical roles in chromatin structure and gene…”
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10
Physical Activity and Brain Health
Published in Genes (17-09-2019)“…Physical activity (PA) has been central in the life of our species for most of its history, and thus shaped our physiology during evolution. However, only…”
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11
Microfluidic Devices for Drug Delivery Systems and Drug Screening
Published in Genes (16-02-2018)“…Microfluidic devices present unique advantages for the development of efficient drug carrier particles, cell-free protein synthesis systems, and rapid…”
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12
A Review of the Important Role of CYP2D6 in Pharmacogenomics
Published in Genes (30-10-2020)“…Cytochrome P450 2D6 ( ) is a critical pharmacogene involved in the metabolism of ~20% of commonly used drugs across a broad spectrum of medical disciplines…”
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13
Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists
Published in Genes (20-06-2018)“…Plants are sessile organisms and, in order to defend themselves against exogenous (a)biotic constraints, they synthesize an array of secondary metabolites…”
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14
Transcriptional Factors Regulate Plant Stress Responses through Mediating Secondary Metabolism
Published in Genes (25-03-2020)“…Plants are adapted to sense numerous stress stimuli and mount efficient defense responses by directing intricate signaling pathways. They respond to…”
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15
The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery
Published in Genes (26-05-2020)“…Significant advances in the management of cystic fibrosis (CF) in recentdecades have dramatically changed the epidemiology and prognosis of this serious…”
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16
Ketogenic Diet and Microbiota: Friends or Enemies?
Published in Genes (15-07-2019)“…Over the last years, a growing body of evidence suggests that gut microbial communities play a fundamental role in many aspects of human health and diseases…”
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17
Genome Size Diversity and Its Impact on the Evolution of Land Plants
Published in Genes (14-02-2018)“…Genome size is a biodiversity trait that shows staggering diversity across eukaryotes, varying over 64,000-fold. Of all major taxonomic groups, land plants…”
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18
Satellite DNA: An Evolving Topic
Published in Genes (18-09-2017)“…Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the eukaryotic genome. Since the discovery of highly repetitive tandem…”
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19
CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function
Published in Genes (23-05-2017)“…DNA methylation is a major epigenetic mark with important roles in genetic regulation. Methylated cytosines are found primarily at CpG dinucleotides, but are…”
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20
Regulation of mTORC2 Signaling
Published in Genes (04-09-2020)“…Mammalian target of rapamycin (mTOR), a serine/threonine protein kinase and a master regulator of cell growth and metabolism, forms two structurally and…”
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