Search Results - "Gener‐Ricos, Georgina"

NPM1‐mutated myeloid neoplasms are a unique entity not defined by bone marrow blast percentage by Gener‐Ricos, Georgina, Bataller, Alex, Rodriguez‐Sevilla, Juan Jose, Chien, Kelly S., Quesada, Andres E., Almanza‐Huante, Emmanuel, Hammond, Danielle, Sasaki, Koji, DiNardo, Courtney, Kadia, Tapan, Daver, Naval, Borthakur, Gautam, Issa, Ghayas C., Short, Nicholas J., Kanagal‐Shamanna, Rashmi, Kantarjian, Hagop M., Garcia‐Manero, Guillermo, Montalban‐Bravo, Guillermo

“…Introduction NPM1‐mutated (NPM1mut) myeloid neoplasms (MNs) with <20% bone marrow (BM) blasts (NPM1mut MNs<20) are uncommon, and their classification remains…”
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Outcomes of patients with therapy‐related myeloid neoplasms after treatment with poly(ADP‐ribose) polymerase proteins inhibitors for solid tumours by Almanza‐Huante, Emmanuel, Bataller, Alex, Urrutia, Samuel, Gener‐Ricos, Georgina, Briski, Robert Edward, Kanagal‐Shamanna, Rashmi, Lu, Karen H., Westin, Shannon N., Yap, Timothy A., Takahashi, Koichi, Ravandi, Farhad, Alvarado, Yesid, Kadia, Tapan, Sasaki, Koiji, Kantarjian, Hagop M., Garcia‐Manero, Guillermo

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Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study by Muñoz-González, Javier I, Álvarez-Twose, Iván, Jara-Acevedo, María, Zanotti, Roberta, Perkins, Cecelia, Jawhar, Mohamad, Sperr, Wolfgang R, Shoumariyeh, Khalid, Schwaab, Juliana, Greiner, Georg, Henriques, Ana, Caldas, Carolina, Fernández-Giménez, Carlos, Sánchez-Muñoz, Laura, Mayado, Andrea, Pérez-Pons, Alba, Schmitt-Graeff, Annette, Duyster, Justus, Tanasi, Ilaria, Olivieri, Francesco, Mora-Casterá, Elvira, Luna, Irene, Senent, Leonor, Bañas, Maria-Helena, Nuñez-García, Amanda, Jurado-Chacón, Manuel, Martín-Sánchez, Guillermo, Colado, Enrique, Xicoy, Blanca, Gener-Ricós, Georgina, Gotlib, Jason, Bonadonna, Patrizia, Reiter, Andreas, Valent, Peter, García-Montero, Andrés C, Orfao, Alberto

“…Several risk stratification models have been proposed in recent years for systemic mastocytosis but have not been directly compared. Here we designed and…”
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New Mutations in HFE2 and TFR2 Genes Causing Non HFE -Related Hereditary Hemochromatosis by Hernández, Gonzalo, Ferrer-Cortès, Xenia, Venturi, Veronica, Musri, Melina, Pilquil, Martin Floor, Torres, Pau Marc Muñoz, Rodríguez, Ines Hernandez, Mínguez, Maria Àngels Ruiz, Kelleher, Nicholas J, Pelucchi, Sara, Piperno, Alberto, Alberca, Esther Plensa, Ricós, Georgina Gener, Giró, Eloi Cañamero, Pérez-Montero, Santiago, Tornador, Cristian, Villà-Freixa, Jordi, Sánchez, Mayka

“…Hereditary hemochromatosis (HH) is an iron metabolism disease clinically characterized by excessive iron deposition in parenchymal organs such as liver, heart,…”
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Advances in the management of higher-risk myelodysplastic syndromes: future prospects by Gener-Ricos, Georgina, Rodriguez-Sevilla, Juan Jose, Urrutia, Samuel, Bataller, Alex, Bazinet, Alexandre, Garcia-Manero, Guillermo

“…Higher-risk myelodysplastic syndromes (HR-MDS) are defined using a number of prognostic scoring systems that include the degree of cytopenias, percentage of…”
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Germline Predisposition to Myelodysplastic Syndromes by Gener-Ricos, Georgina, Gerstein, Yoheved S., Hammond, Danielle, DiNardo, Courtney D.

“…While germline predisposition to myelodysplastic syndromes is well-established, knowledge has advanced rapidly resulting in more cases of inherited hematologic…”
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NPM1-Mutated Myeloid Neoplasms: Updated Outcomes with High-Intensive Chemotherapy Regardless of the Blast Percentage by Gener-Ricos, Georgina, Bataller, Alex, Almanza-Huante, Emmanuel, Chien, Kelly S., Hammond, Danielle E., Sasaki, Koji, DiNardo, Courtney D., Kadia, Tapan M., Daver, Naval, Borthakur, Gautam, Issa, Ghayas C., Short, Nicholas J., Garcia-Manero, Guillermo, Montalban-Bravo, Guillermo

“…Background: The most recent World Health Organization (WHO) classification has stablished NPM1-mutated myeloid neoplasms (MNs) to be acute myeloid leukemia…”
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TP53 Y220C Mutations in Patients with Myeloid Malignancies by Gener-Ricos, Georgina, Bewersdorf, Jan Philipp, Loghavi, Sanam, Goldberg, Aaron D., Famulare, Christopher, Issa, Ghayas C., Borthakur, Gautam, Kadia, Tapan M., Carter, Bing Z., Patel, Keyur P., Andreeff, Michael, Stein, Eytan M., DiNardo, Courtney D.

“…Background:TP53 gene mutations lead to inactivation of the protein p53, causing genome instability, oncogenesis, and treatment resistance conferring an…”
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Clinical Characteristics and Outcomes of Therapy-Related Chronic Myelomonocytic Leukemia: Analysis of a Large Cohort by Bataller, Alex, Gener-Ricos, Georgina, Almanza, Emmanuel, Urrutia, Samuel, Chien, Kelly S., Hammond, Danielle E., Sasaki, Koji, DiNardo, Courtney D., Ravandi, Farhad, Borthakur, Gautam, Kadia, Tapan M., Kanagal-Shamanna, Rashmi, Kantarjian, Hagop M., Garcia-Manero, Guillermo, Montalban-Bravo, Guillermo

“…Introduction: Therapy-related myeloid neoplasms are associated with a previous exposure to cytotoxic agents or ionizing radiation, and account for 10-20% of…”
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Efficacy of immune checkpoint inhibitors for the treatment of advanced melanoma (AM) in patients with concomitant chronic lymphocytic leukemia (CLL) by Cass, Samuel, Tobin, Joshua, Seo, Yongwoo David, Gener-Ricos, Georgina, Keung, Emily Zhi-Yun, Burton, Elizabeth M., Walsh, Danielle M., Davies, Michael A., McQuade, Jennifer Leigh, Lazar, Alexander J., Hampel, Paul Joseph, Wargo, Jennifer Ann, Ferrajoli, Alessandra

“…e19511 Background: CLL is the most prevalent adult leukemia and is associated with an increased risk of melanoma. CLL alters systemic immunity and can induce…”
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A Descriptive Analysis of TP53 Y220C Mutations in Patients with Hematologic Malignancies by Gener-Ricos, Georgina, Sasaki, Koji, Loghavi, Sanam, Maiti, Abhishek, Short, Nicholas, Haddad, Fadi, Daver, Naval, Borthakur, Gautam, Ravandi, Farhad, Kantarjian, Hagop, Patel, Keyur P., Andreeff, Michael, DiNardo, Courtney D.

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Long-Term Follow-up of Low-Dose Dasatinib (50mg Daily) As Frontline Therapy in Newly Diagnosed Chronic Myeloid Leukemia by Gener-Ricos, Georgina, Haddad, Fadi, Sasaki, Koji, Issa, Ghayas C., Skinner, Jeffrey, Takahashi, Koichi, Masarova, Lucia, Burger, Jan A., Borthakur, Gautam, Bose, Prithviraj, Garcia-Manero, Guillermo, Jabbour, Elias, Kantarjian, Hagop

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Clinicopathologic Predictors of Hypomethylating Agent Failure in Patients with Myelodysplastic Syndromes by Chien, Kelly S., Urrutia, Samuel, Li, Ziyi, Kanagal-Shamanna, Rashmi, Abdelhakeem, Ahmed, Abuasab, Tareq, Almanza, Emmanuel, Gener-Ricos, Georgina, Bataller, Alex, Bazinet, Alexandre, Montalban-Bravo, Guillermo, Short, Nicholas J., Jabbour, Elias, Kadia, Tapan M., Ravandi, Farhad, Borthakur, Gautam, Hammond, Danielle E., Swaminathan, Mahesh, Sasaki, Koji, Dong, Xiao Qin, Pierce, Sherry, Kantarjian, Hagop M., Garcia-Manero, Guillermo

“…Background: Hypomethylating agents (HMA), such as decitabine, azacitidine, and oral decitabine/cedazuridine, are standard-of-care therapies for patients with…”
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Cladribine, High-Dose AraC, Plus Gemtuzumab Ozogamicin (CLAG-GO) As Frontline Intensive Therapy for Fit Patients with Core-Binding Factor Acute Myeloid Leukemia: Preliminary Results by Gener-Ricos, Georgina, Borthakur, Gautam, Sasaki, Koji, Tang, Guilin, Montalban-Bravo, Guillermo, Jabbour, Elias, Ohanian, Maro, Yilmaz, Musa, Haddad, Fadi G., Chien, Kelly S., Ishizawa, Jo, Short, Nicholas J., Maiti, Abhishek, Swaminathan, Mahesh, Garcia-Manero, Guillermo, Daver, Naval, DiNardo, Courtney D., Ravandi, Farhad, Kadia, Tapan M.

“…Background: Core-binding factor (CBF) acute myeloid leukemias (AML) are associated with favorable outcomes when treated with intensive therapy regimens,…”
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Performance of the Molecular International Prognostic Scoring System (IPSS-M) in Hypomethylating Agent-Treated Patients with Myelodysplastic Syndromes by Chien, Kelly S., Urrutia, Samuel, Li, Ziyi, Kanagal-Shamanna, Rashmi, Abdelhakeem, Ahmed, Abuasab, Tareq, Almanza, Emmanuel, Gener-Ricos, Georgina, Bataller, Alex, Bazinet, Alexandre, Montalban-Bravo, Guillermo, Short, Nicholas J., Jabbour, Elias, Kadia, Tapan M., Ravandi, Farhad, Borthakur, Gautam, Hammond, Danielle E., Swaminathan, Mahesh, Sasaki, Koji, Dong, Xiao Qin, Pierce, Sherry, Kantarjian, Hagop, Garcia-Manero, Guillermo

“…Background: Patients with myelodysplastic syndromes (MDS) undergo risk stratification with various prognostication tools, such as the International Prognostic…”
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Low-Dose Dasatinib (50 mg Daily) Frontline Therapy in Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia: 5-Year Follow-Up Results by Gener-Ricos, Georgina, Haddad, Fadi G., Sasaki, Koji, Issa, Ghayas C., Skinner, Jeffrey, Masarova, Lucia, Borthakur, Gautam, Alvarado, Yesid, Garcia-Manero, Guillermo, Jabbour, Elias, Kantarjian, Hagop

“…Dasatinib is a BCR::ABL1 tyrosine kinase inhibitor approved as frontline therapy at a 100 mg daily for chronic myeloid leukemia in chronic phase (CML-CP). The…”
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Outcomes of myeloid malignancies in patients previously treated with PARP inhibitors for solid malignancies: A single institution experience by Almanza-Huante, Emmanuel, Bataller, Alex, Urrutia, Samuel, Gener-Ricos, Georgina, Briski, Robert, Kanagal-Shamanna, Rashmi, Lu, Karen H., Westin, Shannon Neville, Yap, Timothy A., Takahashi, Koichi, Ravandi, Farhad, Alvarado Valero, Yesid, Kadia, Tapan M., Sasaki, Koji, Kantarjian, Hagop M., Garcia-Manero, Guillermo

“…e19000 Background: Treatment with Poly(ADP-ribose) Polymerase proteins (PARP) has improved the survival of patients (pts) with solid malignancies harboring a…”
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PHF6 mutations in myelodysplastic syndromes, chronic myelomonocytic leukemia and acute myeloid leukemia by Bataller, Alex, Chien, Kelly S., Sasaki, Koji, Montalban-Bravo, Guillermo, Kanagal-Shamanna, Rashmi, Urrutia, Samuel, Almanza-Huante, Emmanuel, Gener-Ricos, Georgina, Ravandi, Farhad, Jabbour, Elias, Kadia, Tapan, Borthakur, Gautam, Garcia-Manero, Guillermo

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TP53 Y220C mutations in patients with myeloid malignancies by Gener-Ricos, Georgina, Bewersdorf, Jan P, Loghavi, Sanam, Bataller, Alex, Goldberg, Aaron D, Famulare, Christopher, Takahashi, Koichi, Issa, Ghayas C, Borthakur, Gautam, Kadia, Tapan M, Short, Nicholas J, Senapati, Jayastu, Carter, Bing Z, Patel, Keyur P, Kantarjian, Hagop, Andreeff, Michael, Stein, Eytan M, DiNardo, Courtney D

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MDS-531 Risk Stratification in Hypomethylating Agent-Treated Patients With Myelodysplastic Syndromes: A Multivariate Model by Chien, Kelly s., Li, Ziyi, Urrutia, Samuel, Kanagal-Shamanna, Rashmi, Abdelhakeem, Ahmed, Abuasab, Tareq, Almanza, Emmanuel, Gener Ricos, Georgina, Bataller, Alex, Bazinet, Alexandre, Montalban-Bravo, Guillermo, Short, Nicholas, Kadia, Tapan M., Ravandi, Farhad, Borthakur, Gautam, Hammond, Danielle E., Swaminathan, Mahesh, Sasaki, Koji, Qin Dong, Xiao, Pierce, Sherry A., Kantarjian, Hagop M., Garcia-Manero, Guillermo

“…After the availability of next-generation sequencing (NGS) platforms, the Molecular International Prognostic Scoring System (IPSS-M), incorporating genomic…”
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