Search Results - "Genco, C. A."

Immune dysregulation mediated by the oral microbiome: potential link to chronic inflammation and atherosclerosis by Slocum, C., Kramer, C., Genco, C. A.

“…Cardiovascular disease is an inflammatory disorder characterized by the progressive formation of plaque in coronary arteries, termed atherosclerosis. It is a…”
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Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways by HAYASHI, C, GUDINO, C. V, GIBSON, F. C, GENCO, C. A

“…SummaryA hallmark of infection with the gram-negative pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response. P. gingivalis…”
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Innate Immune Signaling and Porphyromonas gingivalis-accelerated Atherosclerosis by Gibson, F.C., Yumoto, H., Takahashi, Y., Chou, H.-H., Genco, C.A.

“…Periodontal diseases are a group of diseases that lead to erosion of the hard and soft tissues of the periodontium, which, in severe cases, can result in tooth…”
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Neisseria gonorrhoeae Infection Protects Human Endocervical Epithelial Cells from Apoptosis via Expression of Host Antiapoptotic Proteins by Follows, S.A, Murlidharan, J, Massari, P, Wetzler, L.M, Genco, C.A

“…Several microbial pathogens can modulate the host apoptotic response to infection, which may contribute to immune evasion. Various studies have reported that…”
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Aging and contribution of MyD88 and TRIF to expression of TLR pathway-associated genes following stimulation with Porphyromonas gingivalis by Shaik-Dasthagirisaheb, Y. B., Huang, N., Weinberg, E. O., Shen, S. S., Genco, C. A., Gibson III, F. C.

“…Background and Objective Periodontal disease is a highly complex chronic inflammatory disease of the oral cavity. Multiple factors influence periodontal…”
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A role for fimbriae in Porphyromonas gingivalis invasion of oral epithelial cells by NJOROGE, T, GENCO, R. J, SOJAR, H. T, HAMADA, N, GENCO, C. A

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Emerging strategies in microbial haem capture by Genco, Caroline Attardo, Dixon, Dabney White

“…Gram‐negative pathogenic bacteria have evolved novel strategies to obtain iron from host haem‐sequestering proteins. These include the production of specific…”
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Periodontal disease and risk of all cancers among male never smokers: an updated analysis of the Health Professionals Follow-up Study by Michaud, D.S., Kelsey, K.T., Papathanasiou, E., Genco, C.A., Giovannucci, E.

“…Periodontal disease has a direct impact on the immune response and has been linked to several chronic diseases, including atherosclerosis and stroke. Few…”
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Inducible nitric oxide synthase mediates bone development and P. gingivalis-induced alveolar bone loss by Gyurko, R., Shoji, H., Battaglino, R.A., Boustany, G., Gibson, F.C., Genco, C.A., Stashenko, P., Van Dyke, T.E.

“…The role of inducible nitric oxide synthase (iNOS) in bone development and bacterially induced periodontal bone loss was examined using mice with targeted…”
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Characterization and Expression of HmuR, a TonB-Dependent Hemoglobin Receptor of Porphyromonas gingivalis by Simpson, W, Olczak, T, Genco, C A

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Distinct Proinflammatory Host Responses to Neisseria gonorrhoeae Infection in Immortalized Human Cervical and Vaginal Epithelial Cells by Fichorova, R N, Desai, P J, Gibson, 3rd, F C, Genco, C A

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Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis by Sroka, A, Sztukowska, M, Potempa, J, Travis, J, Genco, C A

“…Porphyromonas gingivalis can use hemoglobin bound to haptoglobin and heme complexed to hemopexin as heme sources; however, the mechanism by which hemin is…”
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Binding Specificity of the Porphyromonas gingivalis Heme and Hemoglobin Receptor HmuR, Gingipain K, and Gingipain R1 for Heme, Porphyrins, and Metalloporphyrins by Olczak, T, Dixon, D W, Genco, C A

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Prevention of Porphyromonas gingivalis-Induced Oral Bone Loss following Immunization with Gingipain R1 by GIBSON, Frank C, ATTARDO GENCO, Caroline

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Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalis by Cutler, C.W., Kalmar, J.R., Genco, C.A.

“…Adult periodontitis is a chronic inflammatory disease that affects over 49 million people in the USA alone. Porphyromonas (formerly Bacteroides) gingivalis, a…”
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A novel mouse model to study the virulence of and host response to Porphyromonas (Bacteroides) gingivalis by GENCO, C. A, CUTLER, C. W, KAPCZYNSKI, D, MALONEY, K, ARNOLD, R. R

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Binding and accumulation of hemin in Porphyromonas gingivalis are induced by hemin by ATTARDO GENCO, C, ODUSANYA, B. M, BROWN, G

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Characterization of a Tn4351-generated hemin uptake mutant of Porphyromonas gingivalis: evidence for the coordinate regulation of virulence factors by hemin by GENCO, C. A, SIMPSON, W, FORNG, R. Y, EGAL, M, ODUSANYA, B. M

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Virulence factors of Porphyromonas gingivalis by Holt, Stanley C., Kesavalu, Lakshmyya, Walker, Stephen, Genco, Caroline Attardo

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Binding and accumulation of hemin in Neisseria gonorrhoeae by DESAI, P. J, NZERIBE, R, GENCO, G. A

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