Search Results - "Genc, Osman"

Anticancer agent ukrain and bortezomib combination is synergistic in 4T1 breast cancer cells by Savran, Bircan, Yerlikaya, Azmi, Erdoğan, Elif, Genç, Osman

“…The identification and in-depth understanding of intracellular signalling pathways led to the synthesis and discovery of many agents targeting cancer cells. In…”
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Orexins increase penicillin-induced epileptic activity by Kortunay, Selim, Erken, Haydar Ali, Erken, Gülten, Genç, Osman, Şahiner, Melike, Turgut, Sebahat, Turgut, Günfer

“…► Orexins are excitatory neuropeptides. ► We investigate the effects of orexins on penicillin-induced epilepsy in rats. ► Orexins cause dramatically increase…”
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Balanced oxidative status by nesfatin-1 in intestinal ischemia-reperfusion by Ayada, Ceylan, Toru, Ümran, Genç, Osman, Akcılar, Raziye, Şahin, Server

“…Ischemia causes reversible or irreversible cell or tissue damage and reperfusion can exaggerate cellular damage. Microvascular dysfunction is induced and…”
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Protective effects of simvastatin administered in the experimental hepatic ischemia-reperfusion injury rat model by Kocak, Fatma Emel, MD, Kucuk, Aysegul, PhD, Ozyigit, Filiz, MD, Tosun, Murat, MD, PhD, Kocak, Cengiz, MD, Kocak, Ahmet, MD, PhD, Ekici, Mehmet Fatih, MD, Yaylak, Faik, MD, Genc, Osman, MD, PhD

“…Abstract Background Hepatic ischemia–reperfusion (I/R) injury is a major complication in clinical practice. Previous studies suggest that statins have…”
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Blood Pressure Measurement in Freely Moving Rats by the Tail Cuff Method by Erken, Haydar Ali, Erken, Gülten, Genç, Osman

“…Inconsistency in consecutive blood pressure values is one of the most frequently observed problems in tail cuff method. The aim of this study was to measure…”
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Orexins cause epileptic activity by Erken, Haydar Ali, Erken, Gülten, Genç, Osman, Kortunay, Selim, Şahiner, Melike, Turgut, Günfer, Turgut, Sebahat

“…► Orexins are excitatory neuropeptides. ► Orexins were intracortically applied to rats. ► Orexins cause epileptic activity in rats. Orexins have been…”
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Exercise and DHA prevent the negative effects of hypoxia on EEG and nerve conduction velocity by Erken, Haydar Ali, Erken, Gülten, Colak, Rıdvan, Genç, Osman

“…It is known that hypoxia has a negative effect on nervous system functions, but exercise and DHA (docosahexaenoic acid) have positive effect. In this study, it…”
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Single dose varenicline may trigger epileptic activity by Erken, Haydar Ali, Erken, Gülten, Şimşek, Hasan, Korkut, Oğuzhan, Koç, Emine Rabia, Yavuz, Özlem, Genç, Osman

“…Varenicline is a new drug for smoking cessation, and its effect on epilepsy is not clear. The aim of this study was to investigate whether different doses of…”
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The effect of ozone on blood pressure in DOCA-salt-induced hypertensive rats by Akcılar, Raziye, Akçer, Sezer, Şimşek, Hasan, Akcılar, Aydın, Bayat, Zeynep, Genç, Osman

“…Hypertension is a risk factor for the cardiovascular diseases. Ozone as a therapeutic agent for the treatment of several disorders. We aimed to observe the…”
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Visfatin and ghrelin: can they be forthcoming biomarkers or new drug targets for asthma? by Toru, Ümran, Ayada, Ceylan, Genç, Osman, Şahin, Server, Arık, Özlem, Acat, Murat, Bulut, İsmet, Çetinkaya, Erdoğan

“…Asthma represents chronic inflammation of the airways and is associated with bronchial hyperresponsiveness and reversible airway obstruction. A novel adipokine…”
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Analysing Instructors' View Regarding the Efficiency of the Turkish History Subjects Presented in Turkey Social Studies Textbooks by Seker, Mustafa, Ilhan, Genç Osman

“…Just like it is the reflex of each nation to teach its own history to the next generations, it is essential that our country is also able to identify the…”
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Evaluation of multidrug resistance-1 gene C>T polymorphism frequency in patients with asthma by Toru, Ümran, Ayada, Ceylan, Genç, Osman, Yaşar, Zehra, Şahin, Server, Taşkın, Emre, Bulut, İsmet, Acat, Murat

“…Asthma is a chronic inflammatory lung disease characterized by bronchial hyperresponsiveness and airflow obstruction. Genetic and oxidative stress factors, in…”
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Angiotensinogen gene M235T and angiotensin II-type 1 receptor gene A/C1166 polymorphisms in chronic obtructive pulmonary disease by Ayada, Ceylan, Toru, Ümran, Genç, Osman, Şahin, Server, Turgut, Sebahat, Turgut, Günfer

“…Chronic obstructive pulmonary disease (COPD) occurs irreversibly and is characterized by progressive airflow obstruction. Renin angiotensin system (RAS) has…”
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Different dose-dependent effects of ebselen in sciatic nerve ischemia-reperfusion injury in rats by Ozyigit, Filiz, Kucuk, Aysegul, Akcer, Sezer, Tosun, Murat, Kocak, Fatma Emel, Kocak, Cengiz, Kocak, Ahmet, Metineren, Hasan, Genc, Osman

“…Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen…”
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APJ receptor A445C gene polymorphism in Turkish patients with coronary artery disease by Akcılar, Raziye, Yümün, Gündüz, Bayat, Zeynep, Donbaloğlu, Okan, Erselcan, Kubilay, Ece, Ezgi, Kökdaşgil, Hülya, Genç, Osman

“…Coronary artery disease (CAD) is a disease in which a waxy substance called plaque builds up inside the coronary arteries. Apelin is a novel endogenous peptide…”
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MDR-1 gene C/T polymorphism in COPD: data from Aegean part of Turkey by Toru, Umran, Ayada, Ceylan, Genç, Osman, Turgut, Sebahat, Turgut, Günfer, Bulut, Ismet

“…Genetic factors, in addition to oxidative stress factors, have been implicated in the development of chronic obstructive pulmonary disease (COPD). Multi-drug…”
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Interaction Between Anemia and Blood Levels of Iron, Zinc, Copper, Cadmium and Lead in Children by TURGUT, Sebahat, POLAT, Aziz, INAN, Murat, TURGUT, Günfer, EMMUNGIL, Gülten, BICAN, Mevlüt, KARAKUS, Tugrul Yasin, GENC, Osman

“…Anemia is a widespread problem among infants and children in many parts of the world, and it is often associated with some trace elements (iron, zinc, copper)…”
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Nephrotoxic effects of varenicline as the most effective drug used for smoking cessation: a preliminary experimental study by Koç, Akif, Erken, Haydar Ali, Koçak, Fatma Emel, Yay, Arzu, Güçlü, Aydin, Sari, Erhan, Şimşek, Hasan, Önder, Gözde Özge, Genç, Osman

“…Purpose Varenicline is a new most effective drug for smoking cessation. Its effect on kidney functions remains unclear. This study purposed to investigate…”
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Proconvulsant Effect of NUCB2/Nesfatin-1 by Erken, Haydar Ali, Koç, Emine Rabia, Erken, Gülten, Genç, Osman, Çelik, Hüseyin Tuğrul, Gökçe, Emre Cemal, Ayada, Ceylan, Turgut, Sebahat, Turgut, Günfer

“…NUCB2/nesfatin-1 has been implicated in various physiological functions such as feeding, drinking and the sleep–wake cycle, but its effect on epileptic…”
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Effects of cadmium and zinc on plasma levels of growth hormone, insulin-like growth factor I, and insulin-like growth factor-binding protein 3 by Turgut, Sebahat, Kaptanoglu, Bünyamin, Turgut, Günfer, Emmungil, Gülten, Genç, Osman

“…Humans are constantly exposed to cadmium (Cd) as a result of the increase in air pollution and cigaret use. Zinc (Zn), which is an essential element for the…”
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