Search Results - "Gen-ichi Atsumi"

Extracellular Vesicles Derived from 3T3-L1 Adipocytes Enhance Procoagulant Activity by Nakatani, Eriko, Naito, Yasuo, Ishibashi, Kenichi, Ohkura, Naoki, Atsumi, Gen-ichi

“…Obesity is associated with the risk of venous thromboembolism. Thrombi are constantly formed via the coagulation cascade and degraded by the fibrinolytic…”
Get full text

Exposure to Stearate Activates the IRE1α/XBP-1 Pathway in 3T3-L1 Adipocytes by Takeda, Yoshihiro, Ishibashi, Kenichi, Kuroda, Yumi, Atsumi, Gen-ichi

“…In the endoplasmic reticulum (ER), accumulation of abnormal proteins with malformed higher-order structures activates signaling pathways (inositol-requiring…”
Get full text

Exposure to Stearate Activates the IRE1α/XBP-1 Pathway in 3T3-L1 Adipocytes by Yoshihiro Takeda, Kenichi Ishibashi, Yumi Kuroda, Gen-ichi Atsumi

“…In the endoplasmic reticulum (ER), accumulation of abnormal proteins with malformed higher-order structures activates signaling pathways (inositol-requiring…”
Get full text

Elevated Expression of Vascular Adhesion Molecule-1, Plasminogen Activator Inhibitor-1, Cyclooxygenase-2, and Thrombomodulin in Human Umbilical Vein Endothelial Cells from Hospitalized Gestational Diabetes Mellitus Patients by Takata, Yuko, Nomura, Kyoko, Ishibashi, Kenichi, Kido, Koichiro, Sasamori, Yukifumi, Hiraike, Haruko, Ayabe, Takuya, Atsumi, Gen-ichi

“…Protein expression in human umbilical vein endothelial cells (HUVECs) is a useful indicator of maternal condition and the intrauterine environment during…”
Get full text

Acidic Sialidase Activity Is Aberrant in Obese and Diabetic Mice by Natori, Yujin, Ohkura, Naoki, Nasui, Miwako, Atsumi, Gen-ichi, Kihara-Negishi, Fumiko

“…Mammalian sialidases (NEU1, NEU2, NEU3 and NEU4) that remove sialic acids from glycoconjugates have been implicated in diverse cellular functions. Human…”
Get full text

Activation of PPARγ at an Early Stage of Differentiation Enhances Adipocyte Differentiation of MEFs Derived from Type II Diabetic TSOD Mice and Alters Lipid Droplet Morphology by Ishibashi, Kenichi, Takeda, Yoshihiro, Nakatani, Eriko, Sugawara, Kana, Imai, Ryo, Sekiguchi, Mayu, Takahama, Risa, Ohkura, Naoki, Atsumi, Gen-ichi

“…Type 2 diabetic Tsumura, Suzuki, obese, diabetes (TSOD) mice gradually gain weight as compared to corresponding Tsumura, Suzuki, non-obesity (TSNO) control…”
Get full text

Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice by Oishi, Katsutaka, Atsumi, Gen-ichi, Sugiyama, Shinobu, Kodomari, Ikuko, Kasamatsu, Manami, Machida, Kazuhiko, Ishida, Norio

“…The Clock gene is a core component of the circadian clock in mammals. We show here that serum levels of triglyceride and free fatty acid were significantly…”
Get full text

Blood coagulation and metabolic profiles in middle-aged male and female ob/ob mice by Ohkura, Naoki, Oishi, Katsutaka, Atsumi, Gen-ichi

“…Obese and diabetic states in humans are associated with an increased incidence of thrombotic diseases caused by various coagulation abnormalities. Genetically…”
Get full text

Genome-wide Expression Analysis of Mouse Liver Reveals CLOCK-regulated Circadian Output Genes by Oishi, Katsutaka, Miyazaki, Koyomi, Kadota, Koji, Kikuno, Reiko, Nagase, Takahiro, Atsumi, Gen-ichi, Ohkura, Naoki, Azama, Takashi, Mesaki, Miho, Yukimasa, Shima, Kobayashi, Hisato, Iitaka, Chisato, Umehara, Takashi, Horikoshi, Masami, Kudo, Takashi, Shimizu, Yoshihisa, Yano, Masahiko, Monden, Morito, Machida, Kazuhiko, Matsuda, Juzo, Horie, Shuichi, Todo, Takeshi, Ishida, Norio

“…CLOCK is a positive component of a transcription/translation-based negative feedback loop of the central circadian oscillator in the suprachiasmatic nucleus in…”
Get full text

Xanthoangelols isolated from Angelica keiskei inhibit inflammatory-induced plasminogen activator inhibitor 1 (PAI-1) production by Ohkura, Naoki, Nakakuki, Yoshitaka, Taniguchi, Masahiko, Kanai, Shiho, Nakayama, Akiko, Ohnishi, Katsunori, Sakata, Toshiyuki, Nohira, Tomoyoshi, Matsuda, Juzo, Baba, Kimiye, Atsumi, Gen-ichi

“…The folk medicine Angelica keiskei (Ashitaba) exhibits antitumor, antioxidant and antidiabetic activities and it has recently attracted attention as a health…”
Get full text

Associations between plasma PAI-1 concentrations and its expressions in various organs in obese model mice by Ohkura, Naoki, Shirakura, Misuzu, Nakatani, Eriko, Oishi, Katsutaka, Atsumi, Gen-ichi

Get full text

Regulatory Functions of Phospholipase A2 by Murakami, Makoto, Nakatani, Yoshihito, Atsumi, Gen-Ichi, Inoue, Keizo, Kudo, Ichiro

“…Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal…”
Get full text

Activation of PPARγ at an Early Stage of Differentiation Enhances Adipocyte Differentiation of MEFs Derived from Type II Diabetic TSOD Mice and Alters Lipid Droplet Morphology by Kenichi Ishibashi, Yoshihiro Takeda, Eriko Nakatani, Kana Sugawara, Ryo Imai, Mayu Sekiguchi, Risa Takahama, Naoki Ohkura, Gen-ichi Atsumi

“…Type 2 diabetic Tsumura, Suzuki, obese, diabetes (TSOD) mice gradually gain weight as compared to corresponding Tsumura, Suzuki, non-obesity (TSNO) control…”
Get full text

Elaidate, a trans fatty acid, suppresses insulin signaling for glucose uptake in a manner distinct from that of stearate by Ishibashi, Kenichi, Takeda, Yoshihiro, Nakata, Lisa, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Atsumi, Gen-ichi

“…The dietary intake of elaidate (elaidic acid), a trans-fatty acid, is associated with the development of various diseases. Since elaidate is a C18 unsaturated…”
Get full text

Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells by Clay, Carl E., Namen, Andrew M., Atsumi, Gen-ichi, Willingham, Mark C., High, Kevin P., Kute, Timothy E., Trimboli, Anthony J., Fonteh, Alfred N., Dawson, Paul A., Chilton, Floyd H.

“…This study was undertaken to investigate the influence of the peroxisome proliferator-activated receptor γ (PPARγ) agonists on the proliferation, apoptosis and…”
Get full text

Circadian variations in coagulation and fibrinolytic factors among four different strains of mice by Ohkura, Naoki, Oishi, Katsutaka, Sakata, Toshiyuki, Kadota, Koji, Kasamatsu, Manami, Fukushima, Nanae, Kurata, Ayako, Tamai, Yoko, Shirai, Hidenori, Atsumi, Gen-ichi, Ishida, Norio, Matsuda, Juzo, Horie, Shuichi

“…This study examined circadian variation in coagulation and fibrinolytic parameters among Jcl:ICR, C3H/HeN, BALB/cA, and C57BL/6J strains of mice. Plasma…”
Get more information

Comparative Study of Circadian Variation in Numbers of Peripheral Blood Cells among Mouse Strains: Unique Feature of C3H/HeN Mice by Ohkura, Naoki, Oishi, Katsutaka, Sekine, Yuji, Atsumi, Gen-ichi, Ishida, Norio, Matsuda, Juzo, Horie, Shuichi

“…We examined strain differences in numbers of blood cells and their circadian rhythms in male Jcl:ICR, BALB/cA, C57BL/6J and C3H/HeN mice. The total numbers of…”
Get full text

MAST4 promotes primary ciliary resorption through phosphorylation of Tctex-1 by Sakaji, Kensuke, Ebrahimiazar, Sara, Harigae, Yasuhiro, Ishibashi, Kenichi, Sato, Takeya, Yoshikawa, Takeo, Atsumi, Gen-ichi, Sung, Ching-Hwa, Saito, Masaki

“…The primary cilium undergoes cell cycle–dependent assembly and disassembly. Dysregulated ciliary dynamics are associated with several pathological conditions…”
Get full text

Differentiation with elaidate tends to impair insulin-dependent glucose uptake and GLUT4 translocation in 3T3-L1 adipocytes by Ishibashi, Kenichi, Nehashi, Kana, Oshima, Toshiyuki, Ohkura, Naoki, Atsumi, Gen-Ichi

“…Development of type 2 diabetes mellitus and insulin resistance is associated with a quality of dietary fatty acids such as saturated and unsaturated fatty…”
Get more information

Release of secretory phospholipase A2 from rat neuronal cells and its possible function in the regulation of catecholamine secretion by Matsuzawa, A, Murakami, M, Atsumi, G, Imai, K, Prados, P, Inoue, K, Kudo, I

“…Here we show that secretory phospholipase A2 (sPLA2) that is immunochemically indistinguishable from type II sPLA2 is (i) stored in neuroendocrine cells, (ii)…”
Get full text