Search Results - "Gemmill, R. M."

High-Throughput Tissue Microarray Analysis Used to Evaluate Biology and Prognostic Significance of the E-Cadherin Pathway in Non–Small-Cell Lung Cancer by BREMNES, R. M, VEVE, R, GABRIELSON, E, HIRSCH, F. R, BARON, A, BEMIS, L, GEMMILL, R. M, DRABKIN, H. A, FRANKLIN, W. A

“…E-cadherin (E-cad) and its associated intracellular molecules, catenins, are critical for intercellular epithelial adhesion and are often expressed in…”
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Mutations of the β- and γ-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas by UEDA, M, GEMMILL, R. M, WEST, J, WINN, R, SUGITA, M, TANAKA, N, UEKI, M, DRABKIN, H. A

“…Beta-catenin forms complexes with Tcf and Lef-1 and functions as a transcriptional activator in the Wnt signalling pathway. Although recent investigations have…”
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Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma by GEMMILL, R. M, ZHOU, M, COSTA, L, KORCH, C, BUKOWSKI, R. M, DRABKIN, H. A

“…Epidermal growth factor receptor (EGFR) and tumour growth factor alpha (TGFalpha) are frequently overexpressed in renal cell carcinoma (RCC) yet responses to…”
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RING-dependent tumor suppression and G2 M arrest induced by the TRC8 hereditary kidney cancer gene by BRAUWEILER, A, LORICK, K. L, LEE, J. P, TSAI, Y. C, CHAN, D, WEISSMAN, A. M, DRABKIN, H. A, GEMMILL, R. M

“…TRC8/RNF139 and von Hippel-Lindau (VHL) both encode E3 ubiquitin (Ub) ligases mutated in clear-cell renal carcinomas (ccRCC). VHL, inactivated in nearly 70% of…”
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Hox expression in AML identifies a distinct subset of patients with intermediate cytogenetics by ROCHE, J, ZENG, C, BARON, A, GADGIL, S, GEMMILL, R. M, TIGAUD, I, THOMAS, X, DRABKIN, H. A

“…We previously reported that favorable and poor prognostic chromosomal rearrangements in acute myeloid leukemia (AML) were associated with distinct levels of…”
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Chromosome 3p14 Homozygous Deletions and Sequence Analysis of FRA3B by Boldog, Ferenc, Gemmill, Robert M., West, James, Robinson, Misi, Robinson, Linda, Li, Efang, Roche, Joelle, Todd, Sean, Waggoner, Barbara, Lundstrom, Ron, Jacobson, Jan, Mullokandov, Michael R., Klinger, Harold, Drabkin, Harry A.

“…Loss of heterozygosity (LOH) involving 3p occurs in many carcinomas but is complicated by the identification of four distinct homozygous deletion regions. One…”
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Minimal residual disease (MRD) in remission t(8;21) AML and in vivo differentiation detected by FISH and CD34+ cell sorting by VARELLA-GARCIA, M, HOGAN, C. J, MCGAVRAN, L, GEMMILL, R. M, BERGER, R, DRABKIN, H. A, ODOM, L. F, MURATA-COLLINS, I. L, AI, H, CHEN, L, RICHKIND, K, PASKULIN, G, ANDREEFF, M, BRIZARD, A

“…Many patients with t(8;21) AML have residual positive cells during remission. We previously developed D-FISH probes that detect both derivative chromosomes and…”
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Homozygous deletions of human chromosome 3p in lung tumors by TODD, S, FRANKLIN, W. A, VARELLA-GARCIA, M, KENNEDY, T, HILLIKER, C. E, HAHNER, L. JR, ANDERSON, M, WIEST, J. S, DRABKIN, H. A, GEMMILL, R. M

“…Cytogenetic and loss of heterozygosity (LOH) studies have demonstrated that deletions of chromosome 3p occur at a high frequency in all forms of lung cancer…”
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Positional Cloning of the Hereditary Renal Carcinoma 3;8 Chromosome Translocation Breakpoint by Boldog, Ferenc L., Gemmill, Robert M., Wilke, Charles M., Glover, Thomas W., Nilsson, Ann-Sofie, Chandrasekharappa, Settara C., Brown, Robert S., Li, Frederick P., Drabkin, Harry A.

“…The chromosome (p14.2;q24.1) translocation t(3;8)has been associated with hereditary renal cancer in one family. Based on cytogenetic analyses and…”
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Chromosomes in solid tumors and beyond by SANDBERG, A. A, TURC-CAREL, C, GEMMILL, R. M

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DEF-3(G16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC by DRABKIN, H. A, WEST, J. D, HOTFILDER, M, HENG, Y. M, ERICKSON, P, CALVO, R, DALMAU, J, GEMMILL, R. M, SABLITZKY, F

“…DEF-3(g16/NY-LU-12) encodes a novel RNA binding protein isolated by positional cloning from an SCLC homozygous deletion region in 3p21.3 and, in parallel, as a…”
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Chromosomal duplication accompanies allelic loss in non-small cell lung carcinoma by VARELLA-GARCIA, M, GEMMILL, R. M, RABENHORST, S. H, LOTTO, A, DRABKIN, H. A, ARCHER, P. A, FRANKLIN, W. A

“…Hemizygous deletion in the short (p) arm of chromosome 3 is a common finding in non-small cell lung carcinoma (NSCLC) and is postulated to be a crucial early…”
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A second-generation YAC contig map of human chromosome 3 by Gemmill, R M, Chumakov, I, Scott, P, Waggoner, B, Rigault, P, Cypser, J, Chen, Q, Weissenbach, J, Gardiner, K, Wang, H

“…A map of human chromosome 3 which integrates both physical and genetic data has been developed from the fusion of two large collections of markers and…”
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WNT7a Induces E-Cadherin in Lung Cancer Cells by Ohira, Tatsuo, Gemmill, Robert M., Ferguson, Kevin, Kusy, Sophie, Roche, Joëlle, Brambilla, Elisabeth, Zeng, Chan, Baron, Anna, Bemis, Lynne, Erickson, Paul, Wilder, Elizabeth, Rustgi, Anil, Kitajewski, Jan, Gabrielson, Edward, Bremnes, Roy, Franklin, Wilbur, Drabkin, Harry A.

“…E-cadherin loss in cancer is associated with de-differentiation, invasion, and metastasis. Drosophila DE-cadherin is regulated by Wnt/β-catenin signaling,…”
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Report of the sixth international workshop on human chromosome 3 mapping 1995 by Naylor, S L, Carritt, B, Boileau, C, Beroud, C, Alexander, C, Allderdice, P, Alimov, A, Ashworth, T, Bonifas, J, Bugert, P, Buys, C H, Chipperfield, M A, Deng, G, Drabkin, H, Gemmill, R M, Grompe, M, Joensuu, T, Jonasdottir, A, Gizatullin, R, Krols, L, Leach, R J, Lott, S T, Killary, A, Martinsson, T, Messiaen, L

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Altered HOX and WNT7A Expression in Human Lung Cancer by Calvo, Roser, West, James, Franklin, Wilbur, Erickson, Paul, Bemis, Lynne, Li, Efang, Helfrich, Barbara, Bunn, Paul, Roche, Joelle, Brambilla, Elisabeth, Rosell, Rafael, Gemmill, Robert M., Drabkin, Harry A.

“…HOX genes encode transcription factors that control patterning and cell fates. Alterations in HOX expression have been clearly implicated in leukemia, but…”
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Multicolor FISH mapping of YAC clones in 3p14 and identification of a YAC spanning both FRA3B and the t(3;8) associated with hereditary renal cell carcinoma by Wilke, C M, Guo, S W, Hall, B K, Boldog, F, Gemmill, R M, Chandrasekharappa, S C, Barcroft, C L, Drabkin, H A, Glover, T W

“…Human chromosome band 3p14 contains two tightly linked cytogenetic markers of broad interest, FRA3B and the t(3;8) breakpoint associated with hereditary renal…”
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Selective Suppression of In Vivo Tumorigenicity by Semaphorin SEMA3F in Lung Cancer Cells by Kusy, Sophie, Nasarre, Patrick, Chan, Daniel, Potiron, Vincent, Meyronet, David, Gemmill, Robert M., Constantin, Bruno, Drabkin, Harry A., Roche, Joëlle

“…Loss of the 3p21.3-encoded semaphorins, SEMA3B and SEMA3F is implicated in lung cancer development. Although both antagonize VEGF binding/response to…”
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Assignment of the human slow twitch skeletal muscle/cardiac troponin C gene (TNNC1) to human chromosome 3p21.3-->3p14.3 using somatic cell hybrids by Song, W J, Van Keuren, M L, Drabkin, H A, Cypser, J R, Gemmill, R M, Kurnit, D M

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High A + T content conserved in DNA sequences upstream of leuABCD in Escherichia coli and Salmonella typhimurium by HAUGHIN, G. W, WESSLER, S. R, GEMMILL, R. M, CALVO, J. M

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