Search Results - "Gemmer, Jennifer Y"

MK1775, a selective Wee1 inhibitor, shows single-agent antitumor activity against sarcoma cells by Kreahling, Jenny M, Gemmer, Jennifer Y, Reed, Damon, Letson, Douglas, Bui, Marilyn, Altiok, Soner

“…Wee1 is a critical component of the G(2)-M cell-cycle checkpoint control and mediates cell-cycle arrest by regulating the phosphorylation of CDC2. Inhibition…”
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Abstract 3047: MK1775, a selective Wee1 inhibitor shows antitumor activity against sarcoma cells by Kreahling, Jenny M., Foroutan, Parastou, Gemmer, Jennifer Y., Martinez, Gary, Reed, Damon, Letson, Douglas, Bui, Marilyn, Gillies, Rober J., Altiok, Soner

“…Abstract Sarcomas are rare and heterogeneous mesenchymal tumors affecting both pediatric and adult populations with more than 70 recognized histologies…”
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Abstract 5048: Targeting regulators of Chk1 to enhance cytotoxic efficacy of HDAC inhibitors by Kreahling, Jenny M., Gemmer, Jennifer Y., Ma, Yihong, Cress, Douglas, Johnson, Jackie, Chellappan, Srikumar P., Altiok, Soner

“…Abstract Introduction: Predicting and overcoming drug resistance is a major difficulty facing the efficacy of drugs in clinical trials. Histone deacetylase…”
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