Search Results - "Gemei, Marica"
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“Molecular Anatomy”: a new multi-dimensional hierarchical scaffold analysis tool
Published in Journal of cheminformatics (23-07-2021)“…The scaffold representation is widely employed to classify bioactive compounds on the basis of common core structures or correlate compound classes with…”
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miR-142–3p Down-Regulation Contributes to Thyroid Follicular Tumorigenesis by Targeting ASH1L and MLL1
Published in The journal of clinical endocrinology and metabolism (01-01-2015)“…Context: A previous micro-RNA expression profile of thyroid follicular adenomas identified miR-142 precursor among the miRNAs downregulated in the neoplastic…”
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3
CD66c is a novel marker for colorectal cancer stem cell isolation, and its silencing halts tumor growth in vivo
Published in Cancer (15-02-2013)“…BACKGROUND: Despite the well recognized expression of the cell surface markers cluster of differentiation 44 (homing cell adhesion molecule) and CD133…”
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Binding Mode Exploration of B1 Receptor Antagonists' by the Use of Molecular Dynamics and Docking Simulation-How Different Target Engagement Can Determine Different Biological Effects
Published in International journal of molecular sciences (16-10-2020)“…The kinin B1 receptor plays a critical role in the chronic phase of pain and inflammation. The development of B1 antagonists peaked in recent years but almost…”
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Postoperative Detection of Circulating Tumor Cells Predicts Tumor Recurrence in Colorectal Cancer Patients
Published in Journal of gastrointestinal surgery (01-10-2013)“…Introduction Circulating tumor cells are thought to play a crucial role in the development of distant metastases. Their detection in the blood of colorectal…”
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CD26-positive/CD326-negative circulating cancer cells as prognostic markers for colorectal cancer recurrence
Published in Oncology letters (01-02-2015)“…The present study evaluated the presence and clinical relevance of a cluster of differentiation (CD)26+/CD326− subset of circulating tumor cells (CTCs) in pre-…”
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HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels
Published in Oncotarget (30-05-2014)Get full text
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Diminution of eIF4E activity suppresses parkin mutant phenotypes
Published in Gene (2011)“…Mutations in the human parkin ( PARK2) gene cause autosomal recessive-juvenile Parkinson's disease (AR-JP). In Drosophila melanogaster, mutant parkin alleles…”
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Detection of erbB2 copy number variations in plasma of patients with esophageal carcinoma
Published in BMC cancer (11-04-2011)“…Mortality is high in patients with esophageal carcinoma as tumors are rarely detected before the disease has progressed to an advanced stage. Here, we sought…”
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The percentage of CD133+ cells in human colorectal cancer cell lines is influenced by Mycoplasma hyorhinis infection
Published in BMC cancer (30-03-2010)“…Mollicutes contamination is recognized to be a critical issue for the cultivation of continuous cell lines. In this work we characterized the effect of…”
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ADPredict: ADP-ribosylation site prediction based on physicochemical and structural descriptors
Published in Bioinformatics (01-08-2018)“…Abstract Motivation ADP-ribosylation is a post-translational modification (PTM) implicated in several crucial cellular processes, ranging from regulation of…”
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma
Published in Cell death and differentiation (01-11-2016)“…Colorectal carcinoma (CRC) is a common cause of cancer-related death worldwide. Indeed, treatment failures are triggered by cancer stem cells (CSCs) that give…”
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Novel selective, potent naphthyl TRPM8 antagonists identified through a combined ligand- and structure-based virtual screening approach
Published in Scientific reports (08-09-2017)“…Transient receptor potential melastatin 8 (TRPM8), a nonselective cation channel, is the predominant mammalian cold temperature thermosensor and it is…”
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Surface proteomic analysis of differentiated versus stem-like osteosarcoma human cells
Published in Proteomics (Weinheim) (01-11-2013)“…Cancer stem cell characterization represents a breakthrough in cancer research. Despite evidence showing the existence and the role of cancer stem cells in…”
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HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells
Published in Expert opinion on therapeutic targets (02-10-2016)“…Glioblastoma multiforme (GBM) develops from a small subpopulation of stem-like cells, which are endowed with the ability to self-renew, proliferate and give…”
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CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice
Published in Blood (11-11-2010)“…Acute myeloid leukemia (AML) with mutated NPM1 shows distinctive biologic and clinical features, including absent/low CD34 expression, the significance of…”
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TRAP1 regulates stemness through Wnt/[beta]-catenin pathway in human colorectal carcinoma
Published in Cell death and differentiation (01-11-2016)“…Colorectal carcinoma (CRC) is a common cause of cancer-related death worldwide. Indeed, treatment failures are triggered by cancer stem cells (CSCs) that give…”
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Protein cross-talk in CD133+ colon cancer cells indicates activation of the Wnt pathway and upregulation of SRp20 that is potentially involved in tumorigenicity
Published in Proteomics (Weinheim) (01-06-2012)“…The cancer stem cell (CSC) theory represents a breakthrough in cancer research. We characterized the protein pattern of CSCs to identify specific intracellular…”
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Cytometric Profiling of CD133+ Cells in Human Colon Carcinoma Cell Lines Identifies a Common core Phenotype and Cell Type-specific Mosaics
Published in The International journal of biological markers (01-07-2013)“…In colorectal cancer, CD133+ cells from fresh biopsies proved to be more tumorigenic than their CD133– counterparts. Nevertheless, the function of CD133…”
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Publisher Correction: Novel selective, potent naphthyl TRPM8 antagonists identified through a combined ligand- and structure-based virtual screening approach
Published in Scientific reports (06-03-2018)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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