Search Results - "Gelyana, Eilrayna"

Continuing the search for fluid biomarkers to enhance Huntington's disease staging and therapeutic response by Gelyana, Eilrayna, Khamishon, Rebecca, Bang, Jee

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Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid β-Protein Oligomers by Xu, Huixin, Gelyana, Eilrayna, Rajsombath, Molly, Yang, Ting, Li, Shaomin, Selkoe, Dennis

“…Microglial dysfunction is increasingly recognized as a key contributor to the pathogenesis of Alzheimer's disease (AD). Environmental enrichment (EE) is well…”
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Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide by Zunke, Friederike, Moise, Alexandra C., Belur, Nandkishore R., Gelyana, Eilrayna, Stojkovska, Iva, Dzaferbegovic, Haris, Toker, Nicholas J., Jeon, Sohee, Fredriksen, Kristina, Mazzulli, Joseph R.

“…α-Synuclein (α-syn) aggregation is a key event in Parkinson’s disease (PD). Mutations in glycosphingolipid (GSL)-degrading glucocerebrosidase are risk factors…”
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Pathological α-syn aggregation is mediated by glycosphingolipid chain length and the physiological state of α-syn in vivo by Fredriksen, Kristina, Aivazidis, Stefanos, Sharma, Karan, Burbidge, Kevin J., Pitcairn, Caleb, Zunke, Friederike, Gelyana, Eilrayna, Mazzulli, Joseph R.

“…GBA1 mutations that encode lysosomal β-glucocerebrosidase (GCase) cause the lysosomal storage disorder Gaucher disease (GD) and are strong risk factors for…”
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