Search Results - "Gelozia, Shorena"

One‐Pot Generation of Bicyclo[3.1.0]hexanols and Cyclohexanones by Double Interrupted Nazarov Reactions by Gelozia, Shorena, Kwon, Yonghoon, McDonald, Robert, West, F. G.

“…Organoaluminum‐mediated double interrupted Nazarov cyclization to access bicyclo[3.1.0]hexanols via nucleophilic methyl attack followed by Simmons–Smith‐type…”
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The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C by Li, Monica X., Gelozia, Shorena, Danmaliki, Gaddafi I., Wen, Yurong, Liu, Philip B., Lemieux, M. Joanne, West, Frederick G., Sykes, Brian D., Hwang, Peter M.

“…The compound MCI-154 was previously shown to increase the calcium sensitivity of cardiac muscle contraction. Using solution NMR spectroscopy, we demonstrate…”
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Structures reveal details of small molecule binding to cardiac troponin by Cai, Fangze, Li, Monica X, Pineda-Sanabria, Sandra E, Gelozia, Shorena, Lindert, Steffen, West, Frederick, Sykes, Brian D, Hwang, Peter M

“…Abstract In cardiac and skeletal muscle, the troponin complex turns muscle contraction on and off in a calcium-dependent manner. Many small molecules are known…”
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Designing a High Affinity Cardiac Troponin Activator by Cai, Fangze, Li, Monica, Pineda-Sanabria, Sandra, Gelozia, Shorena, Lindert, Steffen, McCammon, J. Andrew, West, Frederick, Sykes, Brian, Hwang, Peter

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