Search Results - "Gellersen, Birgit"

Cyclic Decidualization of the Human Endometrium in Reproductive Health and Failure by Gellersen, Birgit, Brosens, Jan J

“…Decidualization denotes the transformation of endometrial stromal fibroblasts into specialized secretory decidual cells that provide a nutritive and…”
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Decidualization of the human endometrium: mechanisms, functions, and clinical perspectives by Gellersen, Birgit, Brosens, Ivo A, Brosens, Jan J

“…The fetomaternal interface, consisting of the maternal decidua and the invading fetal trophoblast, critically regulates placental function and the growth and…”
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Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos by Weimar, Charlotte H E, Kavelaars, Annemieke, Brosens, Jan J, Gellersen, Birgit, de Vreeden-Elbertse, Johanna M T, Heijnen, Cobi J, Macklon, Nick S

“…The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women,…”
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HoxA-11 and FOXO1A cooperate to regulate decidual prolactin expression: towards inferring the core transcriptional regulators of decidual genes by Lynch, Vincent J, Brayer, Kathryn, Gellersen, Birgit, Wagner, Günter P

“…During the menstrual cycle, the ovarian steroid hormones estrogen and progesterone control a dramatic transcriptional reprogramming of endometrial stromal…”
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Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors by Schwenke, Maren, Knöfler, Martin, Velicky, Philipp, Weimar, Charlotte H E, Kruse, Michelle, Samalecos, Annemarie, Wolf, Anja, Macklon, Nick S, Bamberger, Ana-Maria, Gellersen, Birgit

“…Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but…”
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Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals by Lynch, Vincent J, Tanzer, Andrea, Wang, Yajun, Leung, Frederick C, Gellersen, Birgit, Emera, Deena, Wagner, Gunter P

“…Evolutionary change in gene regulation can result from changes in cis-regulatory elements, leading to differences in the temporal and spatial expression of…”
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Characterization of a novel telomerase-immortalized human endometrial stromal cell line, St-T1b by Samalecos, Annemarie, Reimann, Katja, Wittmann, Stefanie, Schulte, Heinrich M, Brosens, Jan J, Bamberger, Ana-Maria, Gellersen, Birgit

“…Coordinated differentiation of the endometrial compartments in the second half of the menstrual cycle is a prerequisite for the establishment of pregnancy…”
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CCAAT/Enhancer-binding Proteins Are Mediators in the Protein Kinase A-dependent Activation of the Decidual Prolactin Promoter by Pohnke, Yvonne, Kempf, Rita, Gellersen, Birgit

“…In the course of decidualization, human endometrial stromal cells (ESC) activate the alternative upstream promoter of the decidual prolactin (dPRL) gene. The…”
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Wild-Type p53 Protein Is Up-Regulated upon Cyclic Adenosine Monophosphate-Induced Differentiation of Human Endometrial Stromal Cells by Pohnke, Yvonne, Schneider-Merck, Tanja, Fahnenstich, Jasmin, Kempf, Rita, Christian, Mark, Milde-Langosch, Karin, Brosens, Jan J., Gellersen, Birgit

“…Decidualization of the endometrial stromal compartment is critical for embryo implantation. Initiation of this differentiation process requires elevated…”
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Human Endometrial Stromal Cells Express Novel Isoforms of the Transcriptional Modulator CREM and Up-Regulate ICER in the Course of Decidualization by Gellersen, Birgit, Kempf, Rita, Telgmann, Ralph

“…Decidualization of human endometrial stromal (ES) cells in culture can be triggered by a sustained elevation of intracellular cAMP for several days and is…”
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Systematic Expression Analysis and Antibody Screening Do Not Support the Existence of Naturally Occurring Progesterone Receptor (PR)-C, PR-M, or Other Truncated PR Isoforms by Samalecos, Annemarie, Gellersen, Birgit

“…Functional progesterone withdrawal associated with human parturition has been ascribed to various mechanisms modulating the function of the classical…”
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Expression of the Metastasis Suppressor KAI1 in Decidual Cells at the Human Maternal-Fetal Interface by Gellersen, Birgit, Briese, Juliane, Oberndörfer, Marine, Redlin, Katja, Samalecos, Annemarie, Richter, Dagmar-Ulrike, Löning, Thomas, Schulte, Heinrich-Maria, Bamberger, Ana-Maria

“…At the human maternal-fetal interface, the decidua forms a dense matrix that is believed to limit trophoblast invasion. We investigated whether the metastasis…”
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The motile and invasive capacity of human endometrial stromal cells: implications for normal and impaired reproductive function by Weimar, Charlotte H E, Macklon, Nick S, Post Uiterweer, Emiel D, Brosens, Jan J, Gellersen, Birgit

“…BACKGROUND Mechanisms underlying early reproductive loss in the human are beginning to be elucidated. The migratory and invasive capacity of human endometrial…”
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Functional Characterization of Male Germ Cell-Specific CREM Isoforms by Jaspers, Saskia, Gellersen, Birgit, Kempf, Rita, Samalecos, Annemarie, Bergmann, Martin, Steger, Klaus

“…Due to alternative promoter usage, splicing, and translational initiation, expression of the cAMP‐responsive element modulator (CREM) gene results in the…”
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Human Endometrial Stromal Cell-Trophoblast Interactions: Mutual Stimulation of Chemotactic Migration and Promigratory Roles of Cell Surface Molecules CD82 and CEACAM1 by GELLERSEN, Birgit, WOLF, Anja, KRUSE, Michelle, SCHWENKE, Maren, BAMBERGER, Ana-Maria

“…We have previously shown that the presence of trophoblast cells enhances invasiveness of decidualizing human endometrial stromal cells. The metastasis…”
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Biglycan Gene Expression in the Human Leiomyosarcoma Cell Line SK-UT-1 by Ungefroren, Hendrik, Gellersen, Birgit, Krull, Nora B., Kalthoff, Holger

“…In this study we demonstrate that the gene encoding the small leucine-rich proteoglycan biglycan is expressed in human myometrial tissue and in the human…”
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Expansion of human trophoblastic spheroids is promoted by decidualized endometrial stromal cells and enhanced by heparin-binding epidermal growth factor-like growth factor and interleukin-1β by Gonzalez, Marina, Neufeld, Julia, Reimann, Katja, Wittmann, Stefanie, Samalecos, Annemarie, Wolf, Anja, Bamberger, Ana-Maria, Gellersen, Birgit

“…Successful pregnancy in humans depends on deep invasion of the maternal decidua by extravillous trophoblast cells (EVTs), a process regulated by autocrine and…”
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Activated Protein Kinase A Is Required for Differentiation-Dependent Transcription of the Decidual Prolactin Gene in Human Endometrial Stromal Cells1 by Telgmann, Ralph, Maronde, Erik, Taskén, Kjetil, Gellersen, Birgit

“…Decidualization of human endometrial stromal (ES) cells in vitro is induced by cAMP analogs and ligands that elevate cellular cAMP levels. A marker of this…”
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The uterus under hormonal control – Cycling for life by Brosens, Jan J., Gellersen, Birgit

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Human Endometrial Stromal Cell-Trophoblast Interactions: Mutual Stimulation of Chemotactic Migration and Promigratory Roles of Cell Surface Molecules CD82 and CEACAM11 by Gellersen, Birgit, Wolf, Anja, Kruse, Michelle, Schwenke, Maren, Bamberger, Ana-Maria

“…We have previously shown that the presence of trophoblast cells enhances invasiveness of decidualizing human endometrial stromal cells. The metastasis…”
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