Search Results - "Geller, Eric B."
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Responsive neurostimulation: Review of clinical trials and insights into focal epilepsy
Published in Epilepsy & behavior (01-11-2018)“…The responsive neurostimulator (RNS ®, NeuroPace Inc.) has been available clinically since 2013 for the treatment of medically refractory partial epilepsy…”
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Real‐world experience with direct brain‐responsive neurostimulation for focal onset seizures
Published in Epilepsia (Copenhagen) (01-08-2020)“…Objective The RNS System is a direct brain‐responsive neurostimulation system that is US Food and Drug Administration–approved for adults with medically…”
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De novo mutations in epileptic encephalopathies
Published in Nature (London) (12-09-2013)“…Exome sequencing has found an excess of de novo mutations in the ∼4,000 most intolerant genes in patients with two classical epileptic encephalopathies…”
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Responsive neurostimulation for refractory epilepsy in the pediatric population: A single-center experience
Published in Epilepsy & behavior (01-11-2020)“…Drug-resistant focal epilepsy (DRFE) in children can impair cognition and behavior, and lead to premature death. Increased pediatric epilepsy surgery numbers…”
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Mesial temporal resection following long‐term ambulatory intracranial EEG monitoring with a direct brain‐responsive neurostimulation system
Published in Epilepsia (Copenhagen) (01-03-2020)“…Objective To describe seizure outcomes in patients with medically refractory epilepsy who had evidence of bilateral mesial temporal lobe (MTL) seizure onsets…”
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Total and partial posterior quadrant disconnection for medically refractory epilepsy: A systematic review
Published in Seizure (London, England) (01-10-2021)“…•Total or partial posterior quadrant disconnection (PQD) is a surgical treatment option for medically refractory epilepsy (MRE).•Overall, 75% of patients…”
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Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography
Published in Epilepsia (Copenhagen) (01-06-2015)“…Summary Objective Patients with suspected mesial temporal lobe (MTL) epilepsy typically undergo inpatient video–electroencephalography (EEG) monitoring with…”
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Association of SLC32A1 Missense Variants With Genetic Epilepsy With Febrile Seizures Plus
Published in Neurology (04-05-2021)“…To identify the causative gene in a large unsolved family with genetic epilepsy with febrile seizures plus (GEFS+), we sequenced the genomes of family members,…”
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Vagus nerve stimulation for children with treatment-resistant epilepsy: a consecutive series of 141 cases: Clinical article
Published in Journal of neurosurgery. Pediatrics (01-05-2011)“…Object The authors undertook this study to analyze the efficacy of vagus nerve stimulation (VNS) in a large consecutive series of children 18 years of age and…”
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Impact of Failed Intracranial Epilepsy Surgery on the Effectiveness of Subsequent Vagus Nerve Stimulation
Published in Neurosurgery (01-12-2011)“…Abstract BACKGROUND Using the Cyberonics registry, Amar and colleagues reported poorer efficacy of vagus nerve stimulation (VNS) in patients who failed…”
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Anterior temporal lobectomy with amygdalohippocampectomy for mesial temporal sclerosis: predictors of long-term seizure control
Published in Journal of neurosurgery (01-08-2013)“…In this paper the authors' goal was to identify preoperative variables that predict long-term seizure freedom among patients with mesial temporal sclerosis…”
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AAN Board of Directors recommends formation of a companion association to establish a political action committee
Published in Neurology (11-09-2007)Get full text
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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Published in Nature communications (10-12-2018)“…The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving…”
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Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy
Published in Neurology (01-09-2020)“…OBJECTIVETo prospectively evaluate safety and efficacy of brain-responsive neurostimulation in adults with medically intractable focal onset seizures (FOS)…”
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Ultra-rare genetic variation in common epilepsies: a case-control sequencing study
Published in Lancet neurology (01-02-2017)“…Summary Background Despite progress in understanding the genetics of rare epilepsies, the more common epilepsies have proven less amenable to traditional…”
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GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture
Published in Nature genetics (01-09-2023)“…Epilepsy is a highly heritable disorder affecting over 50 million people worldwide, of which about one-third are resistant to current treatments. Here we…”
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Outcome of Temporal Lobe Epilepsy Surgery Predicted by Statistical Parametric PET Imaging
Published in The Journal of nuclear medicine (1978) (01-07-1996)“…PET is useful in the presurgical evaluation of temporal lobe epilepsy. The purpose of this retrospective study is to assess the clinical use of statistical…”
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Anterior temporal lobectomy with amygdalohippocampectomy for mesial temporal sclerosis: predictors of long-term seizure control: Clinical article
Published in Journal of neurosurgery (01-08-2013)“…Object In this paper the authors' goal was to identify preoperative variables that predict long-term seizure freedom among patients with mesial temporal…”
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Phenotypic analysis of 303 multiplex families with common epilepsies
Published in Brain (London, England : 1878) (01-08-2017)“…Gene identification in epilepsy has mainly been limited to large families segregating genes of major effect and de novo mutations in epileptic…”
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De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies
Published in American journal of human genetics (05-01-2017)Get full text
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