Search Results - "Geller, Anne E"
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The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression
Published in Nature communications (09-02-2022)“…Despite the remarkable success of immunotherapy in many types of cancer, pancreatic ductal adenocarcinoma has yet to benefit. Innate immune cells are critical…”
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A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients
Published in JCI insight (10-05-2021)“…SARS coronavirus 2 (SARS-CoV-2) is a novel viral pathogen that causes a clinical disease called coronavirus disease 2019 (COVID-19). Although most COVID-19…”
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Spatial TIME landscape and its prognostic value in the lung and brain tumor: location matters
Published in Signal transduction and targeted therapy (08-05-2023)Get full text
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Irreversible electroporation augments β-glucan induced trained innate immunity for the treatment of pancreatic ductal adenocarcinoma
Published in Journal for immunotherapy of cancer (01-04-2023)“…BackgroundPancreatic cancer (PC) is a challenging diagnosis that is yet to benefit from the advancements in immuno-oncologic treatments. Irreversible…”
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Unexpected Breg-NK crosstalk in STING agonist therapy
Published in Cellular & molecular immunology (01-12-2022)Get full text
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Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis
Published in Nature immunology (01-02-2023)“…Metastasis is the leading cause of cancer-related deaths and myeloid cells are critical in the metastatic microenvironment. Here, we explore the implications…”
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Gunshot wound injury to the genitourinary tract: a 4-year retrospective review at an academic level 1 trauma center
Published in Translational andrology and urology (31-03-2024)“…Firearm injuries increased significantly during the coronavirus disease 2019 (COVID-19) pandemic. We aimed to describe our experience with patients admitted to…”
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Lactate supports a metabolic-epigenetic link in macrophage polarization
Published in Science advances (12-11-2021)“…Lactate accumulation is a hallmark of solid cancers and is linked to the immune suppressive phenotypes of tumor-infiltrating immune cells. We report herein…”
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Identifying Factors Predicting Prolonged Opioid Use After Mastectomy
Published in Annals of surgical oncology (01-04-2020)“…Background Women who undergo mastectomy for breast cancer may be prone to prolonged opioid use (POU). However, risk factors for long-term opioid use after…”
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Optimizing the Combination of Immunotherapy and Trans-Arterial Locoregional Therapy for Stages B and C Hepatocellular Cancer
Published in Annals of surgical oncology (01-03-2021)“…Hepatocellular carcinoma (HCC), the most common primary hepatic malignancy worldwide, is the second leading cause of cancer-related death. Underlying liver…”
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A Tumor-admixture Model to Interrogate Immune Cell-dependent Tumorigenesis
Published in Bio-protocol (05-03-2023)“…A rigorous determination of effector contributions of tumor-infiltrating immune cells is critical for identifying targetable molecular mechanisms for the…”
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Harnessing the power of trained immunity using yeast-derived β-glucan to prevent pancreatic cancer
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Despite the remarkable success of immunotherapy, pancreatic cancer has yet to benefit. This creates a desperate need for therapies that target…”
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Abstract PR01: Mitochondrial lactate metabolism in M2 macrophage polarization and ACL-dependent histone acetylation
Published in Cancer research (Chicago, Ill.) (01-12-2020)“…Abstract Tumor-associated macrophages polarized to an M2 phenotype (M2-TAMs) promote neo-angiogenesis, tumor-stromal matrix remodeling, and immuno-evasion…”
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Teaching and Learning with Multilingual Faculty
Published in Across the disciplines (21-12-2011)“…This article draws on a survey of 64 self-identified multilingual faculty from across the disciplines who currently teach with writing in English at the…”
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