Search Results - "Gelfand, Jeffrey"

Autoimmune encephalitis after herpes simplex encephalitis: insights into pathogenesis by Gelfand, Jeffrey M

“…There have been substantial advances in the recognition and treatment of autoimmune causes of encephalitis, particularly encephalitis associated with…”
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Remote Physical Activity Monitoring in Neurological Disease: A Systematic Review by Block, Valerie A J, Pitsch, Erica, Tahir, Peggy, Cree, Bruce A C, Allen, Diane D, Gelfand, Jeffrey M

“…To perform a systematic review of studies using remote physical activity monitoring in neurological diseases, highlighting advances and determining gaps…”
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Multiple sclerosis: diagnosis, differential diagnosis, and clinical presentation by Gelfand, Jeffrey M

“…The diagnosis of multiple sclerosis (MS) is based on demonstrating evidence of inflammatory-demyelinating injury within the central nervous system that is…”
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Clofazimine for Babesiosis: Preclinical Data Support a Clinical Trial by Vannier, Edouard, Gelfand, Jeffrey A

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Ocrelizumab and Other CD20+ B-Cell-Depleting Therapies in Multiple Sclerosis by Gelfand, Jeffrey M., Cree, Bruce A. C., Hauser, Stephen L.

“…Selective depletion of CD20 + B cells by anti-CD20 monoclonal antibodies as monotherapy in multiple sclerosis (MS) profoundly suppresses acute inflammatory…”
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Dual blockade of CXCL12‐CXCR4 and PD‐1–PD‐L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of immunosuppression in the tumor microenvironment by Zeng, Yang, Li, Binghao, Liang, Yingying, Reeves, Patrick M., Qu, Xiying, Ran, Chongzhao, Liu, Qiuyan, Callahan, Michael V., Sluder, Ann E., Gelfand, Jeffrey A., Chen, Huabiao, Poznansky, Mark C.

“…ABSTRACTBlockade of immune‐checkpoint programmed cell death protein 1 (PD‐1) or programmed cell death ligand 1 can enhance effector T‐cell responses. However,…”
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Autoimmune Encephalitis Misdiagnosis in Adults by Flanagan, Eoin P, Geschwind, Michael D, Lopez-Chiriboga, A Sebastian, Blackburn, Kyle M, Turaga, Sanchit, Binks, Sophie, Zitser, Jennifer, Gelfand, Jeffrey M, Day, Gregory S, Dunham, S Richard, Rodenbeck, Stefanie J, Clardy, Stacey L, Solomon, Andrew J, Pittock, Sean J, McKeon, Andrew, Dubey, Divyanshu, Zekeridou, Anastasia, Toledano, Michel, Turner, Lindsey E, Vernino, Steven, Irani, Sarosh R

“…Autoimmune encephalitis misdiagnosis can lead to harm. To determine the diseases misdiagnosed as autoimmune encephalitis and potential reasons for…”
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Cell-surface central nervous system autoantibodies: Clinical relevance and emerging paradigms by Irani, Sarosh R., Gelfand, Jeffrey M., Al-Diwani, Adam, Vincent, Angela

“…The recent discovery of several potentially pathogenic autoantibodies has helped identify patients with clinically distinctive central nervous system diseases…”
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Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial by Green, Ari J, Gelfand, Jeffrey M, Cree, Bruce A, Bevan, Carolyn, Boscardin, W John, Mei, Feng, Inman, Justin, Arnow, Sam, Devereux, Michael, Abounasr, Aya, Nobuta, Hiroko, Zhu, Alyssa, Friessen, Matt, Gerona, Roy, von Büdingen, Hans Christian, Henry, Roland G, Hauser, Stephen L, Chan, Jonah R

“…Multiple sclerosis is a degenerative inflammatory disease of the CNS characterised by immune-mediated destruction of myelin and progressive neuroaxonal loss…”
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Risk of Neuroinflammatory Adverse Events With Tumor Necrosis Factor Inhibitor Treatment by Gelfand, Jeffrey M, Yazdany, Jinoos

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Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels by Boronat, Anna, Gelfand, Jeffrey M., Gresa-Arribas, Nuria, Jeong, Hyo-Young, Walsh, Michael, Roberts, Kirk, Martinez-Hernandez, Eugenia, Rosenfeld, Myrna R., Balice-Gordon, Rita, Graus, Francesc, Rudy, Bernardo, Dalmau, Josep

“…Objective: To report a novel cell surface autoantigen of encephalitis that is a critical regulatory subunit of the Kv4.2 potassium channels. Methods: Four…”
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Rethinking the role of hydroxychloroquine in the treatment of COVID‐19 by Meyerowitz, Eric A., Vannier, Augustin G. L., Friesen, Morgan G. N., Schoenfeld, Sara, Gelfand, Jeffrey A., Callahan, Michael V., Kim, Arthur Y., Reeves, Patrick M., Poznansky, Mark C.

“…There are currently no proven or approved treatments for coronavirus disease 2019 (COVID‐19). Early anecdotal reports and limited in vitro data led to the…”
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Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study by Saidha, Shiv, Dr, Sotirchos, Elias S, MD, Ibrahim, Mohamed A, MD, Crainiceanu, Ciprian M, PhD, Gelfand, Jeffrey M, MD, Sepah, Yasir J, MBBS, Ratchford, John N, MD, Oh, Jiwon, FRCPC, Seigo, Michaela A, ScB, Newsome, Scott D, DO, Balcer, Laura J, Prof, Frohman, Elliot M, Prof, Green, Ari J, MD, Nguyen, Quan D, MD, Calabresi, Peter A, Prof

“…Summary Background Microcystic macular oedema (MMO) of the retinal inner nuclear layer (INL) has been identified in patients with multiple sclerosis (MS) by…”
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Distinct HLA associations of LGI1 and CASPR2-antibody diseases by Binks, Sophie, Varley, James, Lee, Wanseon, Makuch, Mateusz, Elliott, Katherine, Gelfand, Jeffrey M, Jacob, Saiju, Leite, M Isabel, Maddison, Paul, Chen, Mian, Geschwind, Michael D, Grant, Eleanor, Sen, Arjune, Waters, Patrick, McCormack, Mark, Cavalleri, Gianpiero L, Barnardo, Martin, Knight, Julian C, Irani, Sarosh R

“…The mechanisms responsible for the generation of LGI1- or CASPR2-antibodies are unknown. Binks et al. describe two strikingly dichotomous HLA-associations,…”
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Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment by Bradshaw, Michael J, Pawate, Siddharama, Koth, Laura L, Cho, Tracey A, Gelfand, Jeffrey M

“…Although often regarded as a protean illness with myriad clinical and imaging manifestations, neurosarcoidosis typically presents as recognizable syndromes…”
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The importance of early immunotherapy in patients with faciobrachial dystonic seizures by Thompson, Julia, Bi, Mian, Murchison, Andrew G, Makuch, Mateusz, Bien, Christian G, Chu, Kon, Farooque, Pue, Gelfand, Jeffrey M, Geschwind, Michael D, Hirsch, Lawrence J, Somerville, Ernest, Lang, Bethan, Vincent, Angela, Leite, Maria I, Waters, Patrick, Irani, Sarosh R

“…Faciobrachial dystonic seizures (FBDS) are the first adult-onset autoantibody-mediated epilepsy. Thompson et al. describe 103 patients with FBDS, and show that…”
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A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis by Ramesh, Akshaya, Schubert, Ryan D., Greenfield, Ariele L., Dandekar, Ravi, Loudermilk, Rita, Sabatino, Joseph J., Koelzer, Matthew T., Tran, Edwina B., Koshal, Kanishka, Kim, Kicheol, Pröbstel, Anne-Katrin, Banerji, Debarko, Guo, Chu-Yueh, Green, Ari J., Bove, Riley M., DeRisi, Joseph L., Gelfand, Jeffrey M., Cree, Bruce A. C., Zamvil, Scott S., Baranzini, Sergio E., Hauser, Stephen L., Wilson, Michael R.

“…Central nervous system B cells have several potential roles in multiple sclerosis (MS): secretors of proinflammatory cytokines and chemokines, presenters of…”
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Risk of Multiple Sclerosis After a Clinically Isolated Syndrome: From Magnetic Resonance Imaging to Oligoclonal Bands to Activated T Cells by Gelfand, Jeffrey M

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A clinical approach to diagnosis of autoimmune encephalitis by Graus, Francesc, Prof, Titulaer, Maarten J, MD, Balu, Ramani, MD, Benseler, Susanne, MD, Bien, Christian G, Prof, Cellucci, Tania, MD, Cortese, Irene, MD, Dale, Russell C, Prof, Gelfand, Jeffrey M, MD, Geschwind, Michael, MD, Glaser, Carol A, MD, Honnorat, Jerome, Prof, Höftberger, Romana, MD, Iizuka, Takahiro, MD, Irani, Sarosh R, MD, Lancaster, Eric, MD, Leypoldt, Frank, MD, Prüss, Harald, MD, Rae-Grant, Alexander, MD, Reindl, Markus, Prof, Rosenfeld, Myrna R, Prof, Rostásy, Kevin, MD, Saiz, Albert, MD, Venkatesan, Arun, MD, Vincent, Angela, Prof, Wandinger, Klaus-Peter, Prof, Waters, Patrick, PhD, Dalmau, Josep, Prof

“…Summary Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. Advances in autoimmune…”
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Microcystic macular oedema in multiple sclerosis is associated with disease severity by GELFAND, Jeffrey M, NOLAN, Rachel, SCHWARTZ, Daniel M, GRAVES, Jennifer, GREEN, Ari J

“…Macular oedema typically results from blood-retinal barrier disruption. It has recently been reported that patients with multiple sclerosis treated with…”
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