Search Results - "Gelenter, Martin D."

From Angstroms to Nanometers: Measuring Interatomic Distances by Solid-State NMR by Shcherbakov, Alexander A., Medeiros-Silva, João, Tran, Nhi, Gelenter, Martin D., Hong, Mei

“…Internuclear distances represent one of the main structural constraints in molecular structure determination using solid-state NMR spectroscopy, complementing…”
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Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR by Elkins, Matthew R., Williams, Jonathan K., Gelenter, Martin D., Dai, Peng, Kwon, Byungsu, Sergeyev, Ivan V., Pentelute, Bradley L., Hong, Mei

“…The influenza M2 protein not only forms a proton channel but also mediates membrane scission in a cholesterol-dependent manner to cause virus budding and…”
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Water orientation and dynamics in the closed and open influenza B virus M2 proton channels by Gelenter, Martin D., Mandala, Venkata S., Niesen, Michiel J. M., Sharon, Dina A., Dregni, Aurelio J., Willard, Adam P., Hong, Mei

“…The influenza B M2 protein forms a water-filled tetrameric channel to conduct protons across the lipid membrane. To understand how channel water mediates…”
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Recombinant Expression and Chemical Amidation of Isotopically Labeled Native Melittin by Gelenter, Martin D., Bax, Ad

“…Post-translational modifications are ubiquitous in the eukaryotic proteome. However, these modifications are rarely incorporated in NMR studies of eukaryotic…”
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Icephobic Surfaces Induced by Interfacial Nonfrozen Water by Chen, Dayong, Gelenter, Martin D, Hong, Mei, Cohen, Robert E, McKinley, Gareth H

“…It is known that smooth, hydrophobic solid surfaces exhibit low ice adhesion values, which have been shown to approach a lower ice adhesion strength limit…”
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Transport-Relevant Protein Conformational Dynamics and Water Dynamics on Multiple Time Scales in an Archetypal Proton Channel: Insights from Solid-State NMR by Mandala, Venkata S., Gelenter, Martin D., Hong, Mei

“…The influenza M2 protein forms a tetrameric proton channel that conducts protons from the acidic endosome into the virion by shuttling protons between water…”
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From Milliseconds to Minutes: Melittin Self-Assembly from Concerted Non-Equilibrium Pressure-Jump and Equilibrium Relaxation Nuclear Magnetic Resonance by Gelenter, Martin D., Yau, Wai-Ming, Anfinrud, Philip A., Bax, Ad

“…Non-equilibrium kinetics techniques like pressure-jump nuclear magnetic resonance (NMR) are powerful in tracking changes in oligomeric populations and are not…”
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Structurally Based Design of Glucagon Mutants That Inhibit Fibril Formation by Gelenter, Martin D, Dregni, Aurelio J, Duan, Pu, Hong, Mei

“…The peptide hormone glucagon is prescribed as a pharmaceutical compound to treat diabetic hypoglycemia. However, at the acidic pH where it is highly soluble,…”
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Efficient 15N–13C Polarization Transfer by Third-Spin-Assisted Pulsed Cross-Polarization Magic-Angle-Spinning NMR for Protein Structure Determination by Gelenter, Martin D, Hong, Mei

“…We introduce a pulsed third-spin-assisted recoupling experiment that produces high-intensity long-range 15N–13C cross peaks using low radiofrequency (rf)…”
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Efficient 15 N- 13 C Polarization Transfer by Third-Spin-Assisted Pulsed Cross-Polarization Magic-Angle-Spinning NMR for Protein Structure Determination by Gelenter, Martin D, Hong, Mei

“…We introduce a pulsed third-spin-assisted recoupling experiment that produces high-intensity long-range N- C cross peaks using low radiofrequency (rf) energy…”
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Pulsed Third-Spin-Assisted Recoupling NMR for Obtaining Long-Range 13 C- 13 C and 15 N- 13 C Distance Restraints by Gelenter, Martin D, Dregni, Aurelio J, Hong, Mei

“…We present a class of pulsed third-spin-assisted recoupling (P-TSAR) magic-angle-spinning solid-state NMR techniques that achieve efficient polarization…”
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Pulsed Third-Spin-Assisted Recoupling NMR for Obtaining Long-Range 13C–13C and 15N–13C Distance Restraints by Gelenter, Martin D, Dregni, Aurelio J, Hong, Mei

“…We present a class of pulsed third-spin-assisted recoupling (P-TSAR) magic-angle-spinning solid-state NMR techniques that achieve efficient polarization…”
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The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations by Gelenter, Martin D., Smith, Katelyn J., Liao, Shu-Yu, Mandala, Venkata S., Dregni, Aurelio J., Lamm, Matthew S., Tian, Yu, Xu, Wei, Pochan, Darrin J., Tucker, Thomas J., Su, Yongchao, Hong, Mei

“…Glucagon and insulin maintain blood glucose homeostasis and are used to treat hypoglycemia and hyperglycemia, respectively, in patients with diabetes. Whereas…”
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Comparative analysis of 13C chemical shifts of β-sheet amyloid proteins and outer membrane proteins by Somberg, Noah H., Gelenter, Martin D., Hong, Mei

“…Cross-β amyloid fibrils and membrane-bound β-barrels are two important classes of β-sheet proteins. To investigate whether there are systematic differences in…”
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Off-resonance 13C–2H REDOR NMR for site-resolved studies of molecular motion by Gelenter, Martin D., Chen, Kelly J., Hong, Mei

“…We introduce a 13 C– 2 H Rotational Echo DOuble Resonance (REDOR) technique that uses the difference between on-resonance and off-resonance 2 H irradiation to…”
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The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers by Mandala, Venkata S., Liao, Shu-Yu, Gelenter, Martin D., Hong, Mei

“…Influenza A and B viruses cause seasonal flu epidemics. The M2 protein of influenza B (BM2) is a membrane-embedded tetrameric proton channel that is essential…”
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2H–13C correlation solid-state NMR for investigating dynamics and water accessibilities of proteins and carbohydrates by Gelenter, Martin D., Wang, Tuo, Liao, Shu-Yu, O’Neill, Hugh, Hong, Mei

“…Site-specific determination of molecular motion and water accessibility by indirect detection of 2 H NMR spectra has advantages over dipolar-coupling based…”
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Transport-Relevant Protein Conformational Dynamics and Water Dynamics on Multiple Timescales in an Archetypal Proton Channel - Insights from Solid-State NMR by Mandala, Venkata S., Gelenter, Martin D., Hong, Mei

“…The influenza M2 protein forms a tetrameric proton channel that conducts protons from the acidic endosome into the virion by shuttling protons between water…”
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Off-resonance 13 C- 2 H REDOR NMR for site-resolved studies of molecular motion by Gelenter, Martin D, Chen, Kelly J, Hong, Mei

“…We introduce a C- H Rotational Echo DOuble Resonance (REDOR) technique that uses the difference between on-resonance and off-resonance H irradiation to detect…”
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Comparative analysis of 13 C chemical shifts of β-sheet amyloid proteins and outer membrane proteins by Somberg, Noah H, Gelenter, Martin D, Hong, Mei

“…Cross-β amyloid fibrils and membrane-bound β-barrels are two important classes of β-sheet proteins. To investigate whether there are systematic differences in…”
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