Search Results - "Geldmacher, D. S."

Realistic expectations for treatment success in Alzheimer's disease by Geldmacher, D S, Frolich, L, Doody, R S, Erkinjuntti, T, Vellas, B, Jones, R W, Banerjee, S, Lin, P, Sano, M

“…Alzheimer's disease (AD) is a progressive degenerative disease that warrants active management to delay or slow progression of its symptoms. The symptoms of AD…”
Get more information

Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer’s disease (MCI and dementia) in primary care: a review and synthesis by Liss, J. L., Seleri Assunção, S., Cummings, J., Atri, A., Geldmacher, D. S., Candela, S. F., Devanand, D. P., Fillit, H. M., Susman, J., Mintzer, J., Bittner, T., Brunton, S. A., Kerwin, D. R., Jackson, W. C., Small, G. W., Grossberg, G. T., Clevenger, C. K., Cotter, V., Stefanacci, R., Wise‐Brown, A., Sabbagh, M. N.

“…The critical role of primary care clinicians (PCCs) in Alzheimer’s disease (AD) prevention, diagnosis and management must evolve as new treatment paradigms and…”
Get full text

Clock Drawing Test in Very Mild Alzheimer's Disease by Esteban-Santillan, Concepcion, Praditsuwan, Rungnirand, Veda, Hideki, Geldmacher, David S.

“…OBJECTIVES: The primary objective of this study was to determine the efficacy of the clock drawing test to predict the presence of very mild Alzheimer's…”
Get full text

Latent information in fluency lists predicts functional decline in persons at risk for Alzheimer disease by Clark, D.G., Kapur, P., Geldmacher, D.S., Brockington, J.C., Harrell, L., DeRamus, T.P., Blanton, P.D., Lokken, K., Nicholas, A.P., Marson, D.C.

“…We constructed random forest classifiers employing either the traditional method of scoring semantic fluency word lists or new methods. These classifiers were…”
Get full text

DNA Replication Precedes Neuronal Cell Death in Alzheimer's Disease by Yang, Yan, Geldmacher, David S, Herrup, Karl

“…Alzheimer's disease (AD) is a devastating dementia of late life that is correlated with a region-specific neuronal cell loss. Despite progress in uncovering…”
Get full text

Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease by Doody, R S, Geldmacher, D S, Gordon, B, Perdomo, C A, Pratt, R D

“…Donepezil hydrochloride is a selective acetylcholinesterase inhibitor approved for the symptomatic treatment of mild to moderately severe Alzheimer disease…”
Get more information

Ectopic Cell Cycle Proteins Predict the Sites of Neuronal Cell Death in Alzheimer's Disease Brain by Busser, Jonathan, Geldmacher, David S, Herrup, Karl

“…Alzheimer's disease (AD) is a major dementing illness characterized by regional concentrations of senile plaques, neurofibrillary tangles, and extensive…”
Get full text

Apathy in Alzheimer's Disease by Landes, Allan M., Sperry, Susan D., Strauss, Milton E., Geldmacher, David S.

“…Apathy, or loss of motivation, is arguably the most common change in behavior in Alzheimer's disease (AD) but is underrecognized. Apathy represents a form of…”
Get full text

Conflicting priorities in Alzheimer's care, primary care, and managed care: who pays the price? by Geldmacher, D S

Get full text

Stimulus Characteristics Determine Processing Approach on Random Array Letter-Cancellation Tasks by Geldmacher, David S

“…Target-to-distractor ratio strongly influences performance on typical random array letter cancellation tasks, suggesting that a “controlled” processing…”
Get full text

The effect of character and array type on visual spatial search quality following traumatic brain injury by HILLS, EVERETT C., GELDMACHER, DAVID S.

“…Disorders of visuomotor function are common following traumatic brain injury TBI, but spatially directed visual attention has received little study in this…”
Get full text

Effect of stimulus number, target-to-distractor ratio, and motor speed on visual spatial search quality following traumatic brain injury by GELDMACHER, DAVID S., HILLS, EVERETT C.

“…The object of this study was to investigate stimulus effects and motor limitations on visuospatial performance after traumatic brain injury TBI. Previous…”
Get full text

Current concepts : Evaluation of dementia by GELDMACHER, D. S, WHITEHOUSE, P. J

Get full text

Activities of daily living as an outcome measure in clinical trials of dementia drugs. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines by Gauthier, S, Bodick, N, Erzigkeit, E, Feldman, H, Geldmacher, D S, Huff, J, Mohs, R, Orgogozo, J M, Rogers, S

Get more information

Alzheimer's Disease: Current Pharmacotherapy in the Context of Patient and Family Needs by Geldmacher, David S.

“…The objective of this paper is to review current evidence and treatment patterns for pharmacotherapy in Alzheimer's disease (AD), with an emphasis on outcomes…”
Get full text

Visuospatial dysfunction in the neurodegenerative diseases by Geldmacher, David S

“…Visuospatial dysfunction is not generally considered a cardinal feature of the common neurodegenerative disorders of late life like Alzheimer's disease (AD),…”
Get full text

Visual field influence on radial line bisection by Geldmacher, D S, Heilman, K M

“…An attentional bias toward far peripersonal space has been proposed as the mechanism underlying inaccurate bisection of lines oriented radially in the sagittal…”
Get more information

Enhancing recovery from ischemic stroke by Geldmacher, D S

“…Despite the intense efforts devoted to preventing and aborting cerebral ischemia, some individuals will continue to have completed infarctions. Failure of…”
Get more information

Treatment of functional decline in adults with Down syndrome using selective serotonin-reuptake inhibitor drugs by Geldmacher, D S, Lerner, A J, Voci, J M, Noelker, E A, Somple, L C, Whitehouse, P J

“…Alzheimer's disease (AD) is a common cause of functional decline in Down syndrome (DS) adults. Acquired cognitive deficits may be difficult to evaluate in the…”
Get more information

Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons by Wu, Qian, Combs, Colin, Cannady, Steven B, Geldmacher, David S, Herrup, Karl

“…Immunocytochemical studies of postmortem human tissue have shown that the neurons at risk for degeneration in Alzheimer’s are marked by the ectopic expression…”
Get full text