Search Results - "Gelderblom, Wentzel"

Fumonisin B1 protects against long-chained polyunsaturated fatty acid-induced cell death in HepG2 cells – implications for cancer promotion by Riedel, Sylvia, Abel, Stefan, Burger, Hester-Mari, Swanevelder, Sonja, Gelderblom, Wentzel C.A.

“…Fumonisin B1 (FB1), a food-borne mycotoxin, is a cancer promoter in rodent liver and augments proliferation of initiated cells while inhibiting the growth of…”
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Antioxidant Activity of the Dihydrochalcones Aspalathin and Nothofagin and Their Corresponding Flavones in Relation to Other Rooibos (Aspalathus linearis) Flavonoids, Epigallocatechin Gallate, and Trolox by Snijman, Petra W, Joubert, Elizabeth, Ferreira, Daneel, Li, Xing-Cong, Ding, Yuanqing, Green, Ivan R, Gelderblom, Wentzel C. A

“…The antioxidant activity of rooibos flavonoids, including the dihydrochalcones aspalathin and nothofagin and their corresponding flavone glycosides, was…”
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Differential Cytotoxicity of Rooibos and Green Tea Extracts against Primary Rat Hepatocytes and Human Liver and Colon Cancer Cells - Causal Role of Major Flavonoids by Samodien, Sedicka, Kock, Maryna de, Joubert, Elizabeth, Swanevelder, Sonja, Gelderblom, Wentzel C. A.

“…Differential anti-proliferative and pro-apoptotic effects of aqueous extracts of green rooibos (Rg; Aspalathus linearis) and green tea (GT; Camellia sinensis)…”
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Autophagy‐induced cell death by aqueous and polyphenol‐enriched extracts of honeybush (Cyclopia spp.) in liver and colon cancer cells by Samodien, Sedicka, Kock, Maryna, Joubert, Elizabeth, Beer, Dalene, Kriel, Jurgen, Gelderblom, Wentzel C. A., Lilly, Mariska

“…The anti‐cancer potential of Cyclopia species (honeybush) has been demonstrated in several models. The present study investigated the effects of aqueous and…”
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Biologically Based Methods for Control of Fumonisin-Producing Fusarium Species and Reduction of the Fumonisins by Alberts, Johanna F, van Zyl, Willem H, Gelderblom, Wentzel C A

“…Infection by the fumonisin-producing Fusarium spp. and subsequent fumonisin contamination of maize adversely affect international trade and economy with…”
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In Vitro Chemopreventive Properties of Green Tea, Rooibos and Honeybush Extracts in Skin Cells by Magcwebeba, Tandeka U, Swart, Pieter, Swanevelder, Sonja, Joubert, Elizabeth, Gelderblom, Wentzel C A

“…The chemopreventive properties of the herbal teas rooibos ( ) and honeybush ( spp.) have been demonstrated on mouse skin in vivo but the underlying mechanisms…”
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Short-Term and Sub-Chronic Dietary Exposure to Aspalathin-Enriched Green Rooibos (Aspalathus linearis) Extract Affects Rat Liver Function and Antioxidant Status by van der Merwe, Johanna Debora, de Beer, Dalene, Joubert, Elizabeth, Gelderblom, Wentzel C A

“…An aspalathin-enriched green rooibos (Aspalathus linearis) extract (GRE) was fed to male Fischer rats in two independent studies for 28 and 90 days. The…”
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Fumonisin B1 as a Urinary Biomarker of Exposure in a Maize Intervention Study Among South African Subsistence Farmers by VAN DER WESTHUIZEN, Liana, SHEPHARD, Gordon S, BURGER, Hester M, RHEEDER, John P, GELDERBLOM, Wentzel C. A, WILD, Christopher P, YUN YUN GONG

“…The consumption of maize highly contaminated with carcinogenic fumonisins has been linked to high oesophageal cancer rates. The aim of this study was to…”
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The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: Quantification of steroid intermediates and end products in H295R cells by Schloms, Lindie, Storbeck, Karl-Heinz, Swart, Pieter, Gelderblom, Wentzel C.A., Swart, Amanda C.

“…► A single UPLC–MS/MS method was developed to quantify 21 steroid metabolites. ► Rooibos, aspalathin and nothofagin reduced basal H295R steroid production…”
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Effect of Species Variation and Processing on Phenolic Composition and In Vitro Antioxidant Activity of Aqueous Extracts of Cyclopia spp. (Honeybush Tea) by Joubert, Elizabeth, Richards, E. Siân, Merwe, J. Debora Van der, De Beer, Dalene, Manley, Marena, Gelderblom, Wentzel c.a

“…The in vitro antioxidant activity of aqueous extracts prepared from four Cyclopia spp. (unfermented and fermented) was assessed using radical (ABTS•+)…”
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Anti-Inflammatory Effects of Aspalathus linearis and Cyclopia spp. Extracts in a UVB/Keratinocyte (HaCaT) Model Utilising Interleukin-1α Accumulation as Biomarker by Magcwebeba, Tandeka, Swart, Pieter, Swanevelder, Sonja, Joubert, Elizabeth, Gelderblom, Wentzel

“…Ultraviolet B (UVB) radiation is one of the major predisposing risk factors of skin cancer. The anticancer and photoprotective effects of unoxidized rooibos (…”
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Biocontrol of Fusarium Species Utilizing Indigenous Rooibos and Honeybush Extracts by Omoruyi, Beauty E, Volschenk, Heinrich, Gelderblom, Wentzel C A, Lilly, Mariska

“…Mycotoxins produced by several Fusarium species have a significant effect on reducing maize yield and grain quality and have led to food safety concerns. The…”
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The effectiveness of regulatory maximum levels for fumonisin mycotoxins in commercial and subsistence maize crops in South Africa by Shephard, Gordon S., Burger, Hester-Mari, Rheeder, John P., Alberts, Johanna F., Gelderblom, Wentzel C.A.

“…The fumonisins are carcinogenic mycotoxins that have been implicated in various adverse human health effects. Recently, the Codex Alimentarius Commission set…”
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Mangiferin glucuronidation: Important hepatic modulation of antioxidant activity by van der Merwe, J. Debora, Joubert, Elizabeth, Manley, Marena, de Beer, Dalene, Malherbe, Christiaan J., Gelderblom, Wentzel C.A.

“…[Display omitted] ► Mangiferin is a natural xanthone C-glucoside with pharmacological properties. ► Its antioxidant properties are fundamental to some of its…”
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Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver by Marnewick, Jeanine L, Van der Westhuizen, Francois H, Joubert, Elizabeth, Swanevelder, Sonja, Swart, Pieter, Gelderblom, Wentzel C.A

“…The chemoprotective properties of unfermented and fermented rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia) herbal teas, and green and black…”
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The antimutagenic activity of the major flavonoids of rooibos ( Aspalathus linearis): Some dose–response effects on mutagen activation–flavonoid interactions by Snijman, Petra W., Swanevelder, Sonja, Joubert, Elizabeth, Green, Ivan R., Gelderblom, Wentzel C.A.

“…The antimutagenic properties of the most prevalent flavonoids in rooibos ( Aspalathus linearis) were compared in the Salmonella typhimurium mutagenicity assay…”
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Enzymatic detoxification of the fumonisin mycotoxins during dry milling of maize by Alberts, Johanna F., Davids, Ibtisaam, Moll, Wulf-Dieter, Schatzmayr, Gerd, Burger, Hester-Mari, Shephard, Gordon S., Gelderblom, Wentzel C.A.

“…Fumonisin esterase FumD (EC 3.1.1.87), FUMzyme® (BIOMIN, Austria), effectively detoxifies fumonisin B mycotoxins (FB) by hydrolysis and removal of the…”
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The risk management dilemma for fumonisin mycotoxins by Shephard, Gordon S., Kimanya, Martin E., Kpodo, Kafui A., Gnonlonfin, G.J. Benoit, Gelderblom, Wentzel C.A.

“…Since the discovery of the fumonisins in 1988, extensive academic studies have generated much knowledge, including data on chemistry, biochemistry, toxicology,…”
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Rural Subsistence Maize Farming in South Africa: Risk Assessment and Intervention models for Reduction of Exposure to Fumonisin Mycotoxins by Alberts, Johanna, Rheeder, John, Gelderblom, Wentzel, Shephard, Gordon, Burger, Hester-Mari

“…Maize is a staple crop in rural subsistence regions of southern Africa, is mainly produced for direct household consumption and is often contaminated with high…”
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In Vitro Hepatic Biotransformation of Aspalathin and Nothofagin, Dihydrochalcones of Rooibos (Aspalathus linearis), and Assessment of Metabolite Antioxidant Activity by van der Merwe, J. Debora, Joubert, Elizabeth, Manley, Marena, de Beer, Dalene, Malherbe, Christiaan J, Gelderblom, Wentzel C. A

“…Aspalathin (2′,3,4,4′,6′-pentahydroxy-3′-C-β-d-glucopyranosyldihydrochalcone) is the major flavonoid present in the South African herbal tea rooibos. In vitro…”
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