Search Results - "Gelardi, Edoardo L. M."

Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis by Gelardi, Edoardo L. M., Caprioglio, Diego, Colombo, Giorgia, Del Grosso, Erika, Mazzoletti, Daniele, Mattoteia, Daiana, Salamone, Stefano, Ferraris, Davide M., Aronica, Eleonora, Nato, Giulia, Buffo, Annalisa, Rizzi, Menico, Magrassi, Lorenzo, Minassi, Alberto, Garavaglia, Silvia

“…Glioblastoma (GBM) is the most aggressive primary brain tumour for which both effective treatments and efficient tools for an early-stage diagnosis are…”
Get full text

A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro by Gelardi, Edoardo L M, Colombo, Giorgia, Picarazzi, Francesca, Ferraris, Davide M, Mangione, Andrea, Petrarolo, Giovanni, Aronica, Eleonora, Rizzi, Menico, Mori, Mattia, La Motta, Concettina, Garavaglia, Silvia

“…Aldehyde dehydrogenase 1A3 (ALDH1A3) belongs to an enzymatic superfamily composed by 19 different isoforms, with a scavenger role, involved in the oxidation of…”
Get full text

Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer by Ferraris, Davide M, Gelardi, Edoardo L M, Garavaglia, Silvia, Miggiano, Riccardo, Rizzi, Menico

“…Dehydrogenases are oxidoreductase enzymes that play a variety of fundamental functions in the living organisms and have primary roles in pathogen survival and…”
Get more information

The non‐swapped monomeric structure of the arginine‐binding protein from Thermotoga maritima by Smaldone, Giovanni, Ruggiero, Alessia, Balasco, Nicole, Abuhammad, Areej, Autiero, Ida, Caruso, Daniela, Esposito, Davide, Ferraro, Giarita, Gelardi, Edoardo L. M., Moreira, Miguel, Quareshy, Mussa, Romano, Maria, Saaret, Annica, Selvam, Irwin, Squeglia, Flavia, Troisi, Romualdo, Kroon-Batenburg, Loes M. J., Esposito, Luciana, Berisio, Rita, Vitagliano, Luigi

“…Domain swapping is a widespread oligomerization process that is observed in a large variety of protein families. In the large superfamily of substrate‐binding…”
Get full text