Search Results - "Geiszler, Philippine C."
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A convenient model of serum-induced reactivity of human astrocytes to investigate astrocyte-derived extracellular vesicles
Published in Frontiers in cellular neuroscience (10-06-2024)“…Extracellular vesicles (EVs) are secreted by all cells in the CNS, including neurons and astrocytes. EVs are lipid membrane enclosed particles loaded with…”
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NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy
Published in Behavioural brain research (26-02-2018)“…•First investigation of the role of NMNAT1 in the early stage of tauopathies in mice.•htau mice display a robust deficit in food burrowing prior to onset of…”
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A novel role for the immunophilin FKBP52 in motor coordination
Published in Behavioural brain research (15-10-2016)“…•The immunophilin FKBP52 is known to modulate hallmarks of Alzheimer’s disease.•Downregulation of FKBP52 levels does not alter cognitive performance with…”
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Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons
Published in Scientific reports (19-03-2018)“…Metabolite profiling is an important tool that may better capture the multiple features of neurodegeneration. With the considerable parallels between mouse and…”
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NAD-biosynthetic enzyme NMNAT1 reduces early behavioral abnormalities in the htau mouse model of tauopathy
Published in Experimental gerontology (01-08-2015)Get full text
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Behavioural phenotype of the hTau murine model of tauopathies
Published in Experimental gerontology (01-07-2013)Get full text
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