Search Results - "Geisler, H."

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data by Badhiwala, Jetan H, Wilson, Jefferson R, Witiw, Christopher D, Harrop, James S, Vaccaro, Alexander R, Aarabi, Bizhan, Grossman, Robert G, Geisler, Fred H, Fehlings, Michael G

“…Although there is a strong biological rationale for early decompression of the injured spinal cord, the influence of the timing of surgical decompression for…”
Get full text

The Origin of High-Frequency Hearing in Whales by Churchill, Morgan, Martinez-Caceres, Manuel, de Muizon, Christian, Mnieckowski, Jessica, Geisler, Jonathan H.

“…Odontocetes (toothed whales) rely upon echoes of their own vocalizations to navigate and find prey underwater [1]. This sensory adaptation, known as…”
Get full text

A supermatrix analysis of genomic, morphological, and paleontological data from crown Cetacea by Geisler, Jonathan H, McGowen, Michael R, Yang, Guang, Gatesy, John

“…Cetacea (dolphins, porpoises, and whales) is a clade of aquatic species that includes the most massive, deepest diving, and largest brained mammals…”
Get full text

Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase 2 study by Ahn, Inhye E., Farooqui, Mohammed Z.H., Tian, Xin, Valdez, Janet, Sun, Clare, Soto, Susan, Lotter, Jennifer, Housel, Stephanie, Stetler-Stevenson, Maryalice, Yuan, Constance M., Maric, Irina, Calvo, Katherine R., Nierman, Pia, Hughes, Thomas E., Saba, Nakhle S., Marti, Gerald E., Pittaluga, Stefania, Herman, Sarah E.M., Niemann, Carsten U., Pedersen, Lone B., Geisler, Christian H., Childs, Richard, Aue, Georg, Wiestner, Adrian

“…The safety and efficacy of ibrutinib (420 mg) in chronic lymphocytic leukemia (CLL) were evaluated in a phase 2 study; 51 patients had TP53 aberration (TP53…”
Get full text

A new fossil species supports an early origin for toothed whale echolocation by Geisler, Jonathan H., Colbert, Matthew W., Carew, James L.

“…Phylogenetic analysis of a new species of fossil toothed whale, Cotylocara macei , from the Oligocene epoch places it in a basal clade of odontocetes, and its…”
Get full text

Treatment of Older Patients with Mantle-Cell Lymphoma by Kluin-Nelemans, H.C, Hoster, E, Hermine, O, Walewski, J, Trneny, M, Geisler, C.H, Stilgenbauer, S, Thieblemont, C, Vehling-Kaiser, U, Doorduijn, J.K, Coiffier, B, Forstpointner, R, Tilly, H, Kanz, L, Feugier, P, Szymczyk, M, Hallek, M, Kremers, S, Lepeu, G, Sanhes, L, Zijlstra, J.M, Bouabdallah, R, Lugtenburg, P.J, Macro, M, Pfreundschuh, M, Procházka, V, Di Raimondo, F, Ribrag, V, Uppenkamp, M, André, M, Klapper, W, Hiddemann, W, Unterhalt, M, Dreyling, M.H

“…This international prospective study showed that maintenance therapy with rituximab was more effective than interferon alfa in prolonging the duration of…”
Get full text

Attenuated evolution of mammals through the Cenozoic by Goswami, Anjali, Noirault, Eve, Coombs, Ellen J., Clavel, Julien, Fabre, Anne-Claire, Halliday, Thomas J. D., Churchill, Morgan, Curtis, Abigail, Watanabe, Akinobu, Simmons, Nancy B., Beatty, Brian L., Geisler, Jonathan H., Fox, David L., Felice, Ryan N.

“…The Cenozoic diversification of placental mammals is the archetypal adaptive radiation. Yet, discrepancies between molecular divergence estimates and the…”
Get full text

New records of the dolphin Albertocetus meffordorum (Odontoceti: Xenorophidae) from the lower Oligocene of South Carolina: Encephalization, sensory anatomy, postcranial morphology, and ontogeny of early odontocetes by Boessenecker, Robert W, Ahmed, Erum, Geisler, Jonathan H

“…We report five new specimens of xenorophid dolphins from North and South Carolina. Four of the specimens represent the xenorophid Albertocetus meffordorum,…”
Get full text

Rituximab Plus Fludarabine and Cyclophosphamide Prolongs Progression-Free Survival Compared With Fludarabine and Cyclophosphamide Alone in Previously Treated Chronic Lymphocytic Leukemia by Robak, Tadeusz, Dmoszynska, Anna, Solal-Céligny, Philippe, Warzocha, Krzysztof, Loscertales, Javier, Catalano, John, Afanasiev, Boris V, Larratt, Loree, Geisler, Christian H, Montillo, Marco, Zyuzgin, Ilya, Ganly, Peter S, Dartigeas, Caroline, Rosta, András, Maurer, Jörg, Mendila, Myriam, Saville, M Wayne, Valente, Nancy, Wenger, Michael K, Moiseev, Sergey I

“…Rituximab, a monoclonal antibody that targets the CD20 cell surface antigen, has clinical activity in patients with non-Hodgkin's lymphoma and other…”
Get full text

Gangliosides: Treatment Avenues in Neurodegenerative Disease by Magistretti, Pierre J, Geisler, Fred H, Schneider, Jay S, Li, P Andy, Fiumelli, Hubert, Sipione, Simonetta

“…Gangliosides are cell membrane components, most abundantly in the central nervous system (CNS) where they exert among others neuro-protective and -restorative…”
Get full text

Real world data on primary treatment for mantle cell lymphoma: a Nordic Lymphoma Group observational study by Abrahamsson, Anna, Albertsson-Lindblad, Alexandra, Brown, Peter N., Baumgartner-Wennerholm, Stefanie, Pedersen, Lars M., D'Amore, Francesco, Nilsson-Ehle, Herman, Jensen, Paw, Pedersen, Michael, Geisler, Christian H., Jerkeman, Mats

“…There is consensus that young patients with mantle cell lymphoma (MCL) should receive intensive immunochemotherapy regimens, but optimal treatment of elderly…”
Get full text

Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial by Farooqui, Mohammed Z H, DO, Valdez, Janet, PA, Martyr, Sabrina, MD, Aue, Georg, MD, Saba, Nakhle, MD, Niemann, Carsten U, MD, Herman, Sarah E M, PhD, Tian, Xin, PhD, Marti, Gerald, MD, Soto, Susan, MSN, Hughes, Thomas E, PharmD, Jones, Jade, MD, Lipsky, Andrew, MD, Pittaluga, Stefania, MD, Stetler-Stevenson, Maryalice, MD, Yuan, Constance, MD, Lee, Yuh Shan, MD, Pedersen, Lone B, Geisler, Christian H, Prof, Calvo, Katherine R, MD, Arthur, Diane C, MD, Maric, Irina, MD, Childs, Richard, MD, Young, Neal S, MD, Wiestner, Adrian, Dr

“…Summary Background Patients with chronic lymphocytic leukaemia (CLL) with TP53 aberrations respond poorly to first-line chemoimmunotherapy, resulting in early…”
Get full text

New Skeletons of the Ancient Dolphin Xenorophus sloanii and Xenorophus simplicidens sp. nov. (Mammalia, Cetacea) from the Oligocene of South Carolina and the Ontogeny, Functional Anatomy, Asymmetry, Pathology, and Evolution of the Earliest Odontoceti by Boessenecker, Robert W., Geisler, Jonathan H.

“…The early diverging, dolphin-sized, cetacean clade Xenorophidae are a short-lived radiation of toothed whales (Odontoceti) that independently evolved two…”
Get full text

New specimens and species of the Oligocene toothed baleen whale Coronodon from South Carolina and the origin of Neoceti by Boessenecker, Robert W, Beatty, Brian L, Geisler, Jonathan H

“…Baleen whales (Mysticeti) are gigantic filter-feeding cetaceans possessing the unique soft tissue structure baleen and lacking adult teeth; Oligocene fossils…”
Get full text

New Evidence of the Feeding Behaviors of Coronodon and the Origin of Filter Feeding in Mysticetes (Mammalia: Cetacea) Revisited by Geisler, Jonathan H, Beatty, Brian L, Boessenecker, Robert W

“…Coronodon includes species of basal toothed mysticetes that were initially interpreted as engaging in raptorial feeding and dental filtration. Here, the…”
Get full text

Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial by Jerkeman, Mats, Eskelund, Christian Winther, Hutchings, Martin, Räty, Riikka, Wader, Karin Fahl, Laurell, Anna, Toldbod, Helle, Pedersen, Lone Bredo, Niemann, Carsten Utoft, Dahl, Christina, Kuitunen, Hanne, Geisler, Christian H, Grønbæk, Kirsten, Kolstad, Arne

“…Regimens based on ibrutinib alone and lenalidomide and rituximab in combination show high activity in patients with relapsed or refractory mantle cell…”
Get full text

Studying missingness in spinal cord injury data: challenges and impact of data imputation by Bourguignon, Lucie, Lukas, Louis P, Guest, James D, Geisler, Fred H, Noonan, Vanessa, Curt, Armin, Brüningk, Sarah C, Jutzeler, Catherine R

“…In the last decades, medical research fields studying rare conditions such as spinal cord injury (SCI) have made extensive efforts to collect large-scale data…”
Get full text

Rituximab Purging and/or Maintenance in Patients Undergoing Autologous Transplantation for Relapsed Follicular Lymphoma: A Prospective Randomized Trial From the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation by PETTENGELL, Ruth, SCHMITZ, Norbert, TO, Bik, GEISLER, Christian H, SCHOTS, Rik, KIMBY, Eva, TAVERNA, Christian J, KOZAK, Tomáš, DREGER, Peter, UDDIN, Ruzena, DE ELVIRA, Carmen Ruiz, GOLDSTONE, Anthony H, GISSELBRECHT, Christian, SMITH, Graeme, PATTON, William N, METZNER, Bernd, CABALLERO, Dolores, TILLY, Herve, WALEWSKI, Jan A, BENCE-BRUCKLER, Isabelle

“…The objective of this randomized trial was to assess the efficacy and safety of rituximab as in vivo purging before transplantation and as maintenance…”
Get full text

Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study by Herman, S E M, Niemann, C U, Farooqui, M, Jones, J, Mustafa, R Z, Lipsky, A, Saba, N, Martyr, S, Soto, S, Valdez, J, Gyamfi, J A, Maric, I, Calvo, K R, Pedersen, L B, Geisler, C H, Liu, D, Marti, G E, Aue, G, Wiestner, A

“…Ibrutinib and other targeted inhibitors of B-cell receptor signaling achieve impressive clinical results for patients with chronic lymphocytic leukemia (CLL)…”
Get full text

The Mantle Cell Lymphoma International Prognostic Index (MIPI) is superior to the International Prognostic Index (IPI) in predicting survival following intensive first-line immunochemotherapy and autologous stem cell transplantation (ASCT) by Geisler, Christian H., Kolstad, Arne, Laurell, Anna, Räty, Riikka, Jerkeman, Mats, Eriksson, Mikael, Nordström, Marie, Kimby, Eva, Boesen, Anne Marie, Nilsson-Ehle, Herman, Kuittinen, Outi, Lauritzsen, Grete F., Ralfkiær, Elisabeth, Ehinger, Mats, Sundström, Christer, Delabie, Jan, Karjalainen-Lindsberg, Marja-Liisa, Brown, Peter, Elonen, Erkki, for the Nordic Lymphoma Group

“…Mantle cell lymphoma (MCL) has a heterogeneous clinical course. The recently proposed Mantle Cell Lymphoma International Prognostic Index (MIPI) predicted the…”
Get full text