Search Results - "Geisen, Mariah E"

Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression by Drury, James, Rychahou, Piotr G, Kelson, Courtney O, Geisen, Mariah E, Wu, Yuanyuan, He, Daheng, Wang, Chi, Lee, Eun Y, Evers, B Mark, Zaytseva, Yekaterina Y

“…Altered fatty acid metabolism continues to be an attractive target for therapeutic intervention in cancer. We previously found that colorectal cancer (CRC)…”
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Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth by Drury, James, Geisen, Mariah E, Tessmann, Josiane Weber, Rychahou, Piotr G, Kelson, Courtney O, He, Daheng, Wang, Chi, Evers, B Mark, Zaytseva, Yekaterina Y

“…Fatty acid synthesis has been extensively investigated as a therapeutic target in cancers, including colorectal cancer (CRC). Fatty acid synthase (FASN), a key…”
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Ca2+-induced myelin pathology precedes axonal spheroid formation and is mediated in part by store-operated Ca2+ entry after spinal cord injury by Ames, Spencer, Adams, Kia, Geisen, Mariah, Stirling, David

“…[INLINE:1] The formation of axonal spheroid is a common feature following spinal cord injury. To further understand the source of Ca2+ that mediates axonal…”
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Upregulation of Fatty Acid Synthase Increases Activity of β-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells by Kelson, Courtney O, Tessmann, Josiane Weber, Geisen, Mariah E, He, Daheng, Wang, Chi, Gao, Tianyan, Evers, B Mark, Zaytseva, Yekaterina Y

“…Dysregulated fatty acid metabolism is an attractive therapeutic target for colorectal cancer (CRC). We previously reported that fatty acid synthase (FASN), a…”
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Repeat intravital imaging of the murine spinal cord reveals degenerative and reparative responses of spinal axons in real-time following a contusive SCI by Rajaee, Arezoo, Geisen, Mariah E., Sellers, Alexandra K., Stirling, David P.

“…Spinal cord injury (SCI) induces a secondary degenerative response that causes the loss of spared axons and worsens neurological outcome. The complex molecular…”
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Ca 2+ -induced myelin pathology precedes axonal spheroid formation and is mediated in part by store-operated Ca 2+ entry after spinal cord injury by Ames, Spencer, Adams, Kia, Geisen, Mariah E, Stirling, David P

“…The formation of axonal spheroid is a common feature following spinal cord injury. To further understand the source of Ca that mediates axonal spheroid…”
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Abstract 414: Targeting lipid metabolism to improve efficacy of braf-targeted therapy in colorectal cancer by Geisen, Mariah E., he, Dang, Wang, Chi, Kolesar, Jill M., Zaytseva, Yekaterina

“…Abstract Background: Aberrant lipid metabolism is associated with poor prognosis in colorectal cancer (CRC). Fatty acid synthase (FASN), a key enzyme of…”
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