Search Results - "Geisen, K"
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Aminoguanidine Treatment Inhibits the Development of Experimental Diabetic Retinopathy
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-1991)“…Retinal capillary closure induced by hyperglycemia is the principal pathophysiologic abnormality underlying diabetic retinopathy, but the mechanisms by which…”
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Incidence of Intra-abdominal Adhesions Following Intraperitoneal Injection of Hemostatic Products in Rabbits
Published in Military medicine (19-08-2024)“…Definitive management of non-compressible intra-abdominal hemorrhage (NCIAH) currently requires a surgeon and operating room capable of performing damage…”
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Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at adipocytes
Published in Hormone and metabolic research (01-09-1996)“…The possibility of an insulin-independent blood glucose decreasing activity of sulfonylureas was re-evaluated. Single dose studies in dogs with different…”
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Cardiovascular effects of conventional sulfonylureas and glimepiride
Published in Hormone and metabolic research (01-09-1996)“…Sulfonylureas have, in the past, been reported to have adverse cardiovascular effects. Glimepiride is a new sulfonylurea. In spite of stimulating less insulin…”
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Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at beta-cells
Published in Hormone and metabolic research (01-09-1996)“…Glimepiride was compared with glibenclamide for its insulin secretion stimulating and beta-cell membrane depolarizing activity as well as for its binding…”
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Analysis of the anorectic efficacy of HMR1426 in rodents and its effects on gastric emptying in rats
Published in International Journal of Obesity (01-02-2004)“…Pharmacodynamics of HMR1426 in rodents. Male and female rats and male mice. 24 h feed consumption was measured. From the time curves IC(50) values of HMR1426…”
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Aminoguanidine does not inhibit the initial phase of experimental diabetic retinopathy in rats
Published in Diabetologia (01-03-1995)“…We have previously shown that long-term administration of aminoguanidine, an inhibitor of advanced glycosylation product formation, reduces the extent of…”
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Special pharmacology of the new sulfonylurea glimepiride
Published in Arzneimittel-Forschung (01-08-1988)“…Glimepiride (Hoe 490) is a new sulfonylurea. After oral administration of Hoe 490 to rabbits, blood glucose was lowered 3.5 times more than after glibenclamide…”
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Long-term continuous intraperitoneal insulin infusion with an implanted remote-controlled insulin infusion device
Published in Diabetes (New York, N.Y.) (01-12-1981)“…Long-term continuous intraperitoneal insulin infusion with an implanted remote-controlled insulin infusion device. K Irsigler , H Kritz , G Hagmüller , M…”
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Dielectric and optical properties of a quasi-ferroelectric PLZT ceramic
Published in Proceedings of the IEEE (01-01-1973)“…Certain compositions within the quaternary lead-lanthanum-titanate-zirconate (PLZT) system exhibit neither a "true" ferroelectric nor a "true" paraelectric…”
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Long-term continuous intraperitoneal insulin infusion with an implanted remote-controlled insulin infusion device
Published in Diabetes (New York, N.Y.) (01-12-1981)“…This is a report of the implantation and first 100-day operation using a remote-controlled programmable insulin infusion device in an insulin-dependent…”
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Synthesis and characterisation of a decapeptide having LH-RH-FSH-RH activity
Published in Biochemical and biophysical research communications (05-11-1971)Get more information
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13
Expanding participation to non-group members in phase III cooperative group treatment trials
Published in Journal of clinical oncology (20-06-2007)“…Abstract only 6533 Background: The NCI initiated the Cancer Trials Support Unit (CTSU) Independent Clinical Research Site (CICRS) Program at the ASCO Annual…”
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Results with a catheterless insulin delivery device implanted in a pancreatectomized dog
Published in Hormone and metabolic research (01-03-1983)Get more information
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Extrapancreatic effects of sulfonylureas — a comparison between glimepiride and conventional sulfonylureas
Published in Diabetes research and clinical practice (1995)“…The contribution of extrapancreatic effects of sulfonylureas to the blood glucose-decreasing activity was re-evaluated in vivo and in vitro with several…”
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Journal Article Conference Proceeding -
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Sorbitol-accumulating pyrimidine derivatives
Published in Arzneimittel-Forschung (01-09-1994)“…The novel compounds SDI 157 (2-methyl-4(4-N,N-dimethylaminosulfonyl-1-piperazino)pyrimid ine, CAS 131816-54-1) and SDI 158…”
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Stabilisation of dissolved proteins against denaturation at hydrophobie interfaces
Published in Diabetologia (01-08-1984)Get full text
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novel antiobesic HMR1426 reduces food intake without affecting energy expenditure in rats
Published in Obesity (Silver Spring, Md.) (01-08-2004)“…Objective: To determine the effect of acute and chronic administration of a new food intake‐reducing compound (HMR1426) with novel mode of action (retardation…”
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Stabilisation of dissolved proteins against denaturation at hydrophobic interfaces
Published in Diabetologia (01-08-1984)“…Studies with insulin delivery devices have shown that denaturation of dissolved proteins at hydrophobic interfaces is a basic obstacle to long-term insulin…”
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