Surprisingly facile C–H activation in the course of oxime-directed catalytic asymmetric hydroboration

[Display omitted] Deuterium-labeling studies carried out in conjunction with investigations into the directed catalytic asymmetric hydroboration of unsaturated oxime ethers reveal a surprisingly facile ortho-metallation or σ-bond metathesis pathway that diverts the expected course of CAHB to a tande...

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Bibliographic Details
Published in:	Tetrahedron letters Vol. 56; no. 23; pp. 3306 - 3310
Main Authors:	Thacker, Nathan C., Shoba, Veronika M., Geis, Andrew E., Takacs, James M.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 03-06-2015
Subjects:	C–H activation Directed metallation Rhodium-catalyzed borylation Rhodium-catalyzed hydroboration Rhodium-catalyzed borylation Directed metallation C–H activation Rhodium-catalyzed hydroboration rhodium-catalyzed borylation C-H activation directed metallation rhodium-catalyzed hydroboration
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Summary:	[Display omitted] Deuterium-labeling studies carried out in conjunction with investigations into the directed catalytic asymmetric hydroboration of unsaturated oxime ethers reveal a surprisingly facile ortho-metallation or σ-bond metathesis pathway that diverts the expected course of CAHB to a tandem C–H activation/hydroboration reaction pathway.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0040-4039 1873-3581
DOI:	10.1016/j.tetlet.2014.12.076