Search Results - "Geirsson, AJ"

FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease by Saevarsdottir, Saedis, Olafsdottir, Thorunn A., Ivarsdottir, Erna V., Halldorsson, Gisli H., Gunnarsdottir, Kristbjorg, Sigurdsson, Asgeir, Johannesson, Ari, Sigurdsson, Jon K., Juliusdottir, Thorhildur, Lund, Sigrun H., Arnthorsson, Asgeir O., Styrmisdottir, Edda L., Gudmundsson, Julius, Grondal, Gerdur M., Steinsson, Kristjan, Alfredsson, Lars, Askling, Johan, Benediktsson, Rafn, Bjarnason, Ragnar, Geirsson, Arni J., Gudbjornsson, Bjorn, Gudjonsson, Hallgrimur, Hjaltason, Haukur, Hreidarsson, Astradur B., Klareskog, Lars, Kockum, Ingrid, Kristjansdottir, Helga, Love, Thorvardur J., Ludviksson, Bjorn R., Olsson, Tomas, Onundarson, Pall T., Orvar, Kjartan B., Padyukov, Leonid, Sigurgeirsson, Bardur, Tragante, Vinicius, Bjarnadottir, Kristbjorg, Rafnar, Thorunn, Masson, Gisli, Sulem, Patrick, Gudbjartsson, Daniel F., Melsted, Pall, Thorleifsson, Gudmar, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari

“…Autoimmune thyroid disease is the most common autoimmune disease and is highly heritable 1 . Here, by using a genome-wide association study of 30,234 cases and…”
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Treatment response and drug retention rates in 24 195 biologic-naïve patients with axial spondyloarthritis initiating TNFi treatment: routine care data from 12 registries in the EuroSpA collaboration by Ørnbjerg, Lykke Midtbøll, Brahe, Cecilie Heegaard, Askling, Johan, Ciurea, Adrian, Mann, Herman, Onen, Fatos, Kristianslund, Eirik Klami, Nordström, Dan, Santos, Maria Jose, Codreanu, Catalin, Gómez-Reino, Juan, Rotar, Ziga, Gudbjornsson, Bjorn, Di Giuseppe, Daniela, Nissen, Michael J, Pavelka, Karel, Birlik, Merih, Kvien, Tore, Eklund, Kari Kalervo, Barcelos, Anabela, Ionescu, Ruxandra, Sanchez-Piedra, Carlos, Tomsic, Matija, Geirsson, Árni Jón, Loft, Anne Gitte, van der Horst-Bruinsma, Irene, Jones, Gareth, Iannone, Florenzo, Hyldstrup, Lise, Krogh, Niels Steen, Hetland, Merete Lund, Østergaard, Mikkel

“…To study drug retention and response rates in patients with axial spondyloarthritis (axSpA) initiating a first tumour necrosis factor inhibitor (TNFi). Data…”
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One‐Year Treatment Outcomes of Secukinumab Versus Tumor Necrosis Factor Inhibitors in Spondyloarthritis: Results From Five Nordic Biologic Registries Including More Than 10,000 Treatment Courses by Glintborg, Bente, Lindström, Ulf, Giuseppe, Daniela Di, Provan, Sella Aarrestad, Gudbjornsson, Bjorn, Hetland, Merete Lund, Michelsen, Brigitte, Wallman, Johan K., Aaltonen, Kalle, Hokkanen, Anna‐Mari, Nordström, Dan, Jørgensen, Tanja Schjødt, Hansen, Rebekka Lund, Geirsson, Arni Jon, Grøn, Kathrine Lederballe, Krogh, Niels Steen, Askling, Johan, Kristensen, Lars Erik, Jacobsson, Lennart T. H.

“…Objective To describe baseline characteristics and to compare treatment effectiveness of secukinumab versus tumor necrosis factor inhibitors (TNFi) in patients…”
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Second and third TNF inhibitors in European patients with axial spondyloarthritis: effectiveness and impact of the reason for switching by Linde, Louise, Ørnbjerg, Lykke Midtbøll, Heegaard Brahe, Cecilie, Wallman, Johan Karlsson, Di Giuseppe, Daniela, Závada, Jakub, Castrejon, Isabel, Díaz-Gonzalez, Federico, Rotar, Ziga, Tomšič, Matija, Glintborg, Bente, Gudbjornsson, Bjorn, Geirsson, Arni Jon, Michelsen, Brigitte, Kristianslund, Eirik Klami, Santos, Maria José, Barcelos, Anabela, Nordström, Dan, Eklund, Kari K, Ciurea, Adrian, Nissen, Michael, Akar, Servet, Hejl Hyldstrup, Lise, Krogh, Niels Steen, Hetland, Merete Lund, Østergaard, Mikkel

“…Abstract Objective To investigate real-world effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) and the…”
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One-Third of European Patients With Axial Spondyloarthritis Reach Pain Remission With Routine Care Tumor Necrosis Factor Inhibitor Treatment by Ørnbjerg, Lykke Midtbøll, Rugbjerg, Kathrine, Georgiadis, Stylianos, Rasmussen, Simon Horskjær, Lindström, Ulf, Pavelka, Karel, Yilmaz, Neslihan, Favalli, Ennio Giulio, Nissen, Michael J, Michelsen, Brigitte, Vieira-Sousa, Elsa, Jones, Gareth T, Ionescu, Ruxandra, Relas, Heikki, Sanchez-Piedra, Carlos, Tomšič, Matija, Geirsson, Arni Jon, van der Horst-Bruinsma, Irene, Askling, Johan, Loft, Anne Gitte, Nekvindova, Lucie, Direskeneli, Haner, Iannone, Florenzo, Ciurea, Adrian, Fagerli, Karen Minde, Santos, Maria José, Macfarlane, Gary J, Codreanu, Catalin, Eklund, Kari, Pombo-Suarez, Manuel, Rotar, Ziga, Gudbjornsson, Bjorn, Rusman, Tamara, Østergaard, Mikkel, Hetland, Merete Lund

“…To investigate the distribution of patient-reported outcomes (PROs) in patients with axial spondyloarthritis (axSpA) initiating a tumor necrosis factor…”
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The impact of a csDMARD in combination with a TNF inhibitor on drug retention and clinical remission in axial spondyloarthritis by Nissen, Michael, Delcoigne, Bénédicte, Di Giuseppe, Daniela, Jacobsson, Lennart, Hetland, Merete Lund, Ciurea, Adrian, Nekvindova, Lucie, Iannone, Florenzo, Akkoc, Nurullah, Sokka-Isler, Tuulikki, Fagerli, Karen Minde, Santos, Maria Jose, Codreanu, Catalin, Pombo-Suarez, Manuel, Rotar, Ziga, Gudbjornsson, Bjorn, van der Horst-Bruinsma, Irene, Loft, Anne Gitte, Möller, Burkhard, Mann, Herman, Conti, Fabrizio, Yildirim Cetin, Gozde, Relas, Heikki, Michelsen, Brigitte, Avila Ribeiro, Pedro, Ionescu, Ruxandra, Sanchez-Piedra, Carlos, Tomsic, Matija, Geirsson, Árni Jón, Askling, Johan, Glintborg, Bente, Lindström, Ulf

“…Many axial spondylarthritis (axSpA) patients receive a conventional synthetic DMARD (csDMARD) in combination with a TNF inhibitor (TNFi). However, the value of…”
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The occurrence of multiple treatment switches in axial spondyloarthritis. Results from five Nordic rheumatology registries by Di Giuseppe, Daniela, Lindström, Ulf, Aaltonen, Kalle, Relas, Heikki, Provan, Sella, Gudbjornsson, Bjorn, Hetland, Merete Lund, Askling, Johan, Kauppi, Markku, Geirsson, Arni Jon, Chatzidionysiou, Katerina, Jørgensen, Tanja Schjødt, Dreyer, Lene, Michelsen, Brigitte, Jacobsson, Lennart, Glintborg, Bente

“…In axial spondyloarthritis (axSpA), switching between multiple biologic or targeted synthetic (b/ts-) DMARDs might indicate difficult-to-treat disease. We…”
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Predictors of ASDAS-CRP inactive disease in axial spondyloarthritis during treatment with TNF-inhibitors: Data from the EuroSpA collaboration by Ørnbjerg, Lykke M., Linde, Louise, Georgiadis, Stylianos, Rasmussen, Simon H., Lindström, Ulf, Askling, Johan, Michelsen, Brigitte, Giuseppe, Daniela Di, Wallman, Johan K., Pavelka, Karel, Závada, Jakub, Nissen, Michael J., Jones, Gareth T., Relas, Heikki, Pirilä, Laura, Tomšič, Matija, Rotar, Ziga, Geirsson, Arni Jon, Gudbjornsson, Bjorn, Kristianslund, Eirik K., van sder Horst-Bruinsma, Irene, Loft, Anne Gitte, Laas, Karin, Iannone, Florenzo, Corrado, Addolorata, Ciurea, Adrian, Santos, Maria J., Santos, Helena, Codreanu, Catalin, Akkoc, Nurullah, Gunduz, Ozgul S., Glintborg, Bente, Østergaard, Mikkel, Hetland, Merete Lund

“…In patients with axial spondyloarthritis (axSpA) initiating their first tumor necrosis factor alpha-inhibitor (TNFi), we aimed to identify common baseline…”
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Corrigendum to ‘Predictors of ASDAS-CRP inactive disease in axial spondyloarthritis during treatment with TNF-inhibitors: data from the EuroSpA collaboration’ [Seminars in Arthritis and Rheumatism 56 (2022) 1-13/152081] by Ørnbjerg, Lykke M., Linde, Louise, Georgiadis, Stylianos, Rasmussen, Simon H., Lindström, Ulf, Askling, Johan, Michelsen, Brigitte, Giuseppe, Daniela Di, Wallman, Johan K., Pavelka, Karel, Závada, Jakub, Nissen, Michael J., Jones, Gareth T., Relas, Heikki, Pirilä, Laura, Tomšič, Matija, Rotar, Ziga, Geirsson, Arni Jon, Gudbjornsson, Bjorn, Kristianslund, Eirik K., van der Horst-Bruinsma, Irene, Loft, Anne Gitte, Laas, Karin, Iannone, Florenzo, Corrado, Addolorata, Ciurea, Adrian, Santos, Maria J., Santos, Helena, Codreanu, Catalin, Akkoc, Nurullah, Gunduz, Ozgul S., Glintborg, Bente, Østergaard, Mikkel, Hetland, Merete Lund

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Drug retention, inactive disease and response rates in 1860 patients with axial spondyloarthritis initiating secukinumab treatment : routine care data from 13 registries in the EuroSpA collaboration by Michelsen, Brigitte, Lindström, Ulf, Codreanu, Catalin, Ciurea, Adrian, Zavada, Jakub, Loft, Anne Gitte, Pombo-Suarez, Manuel, Onen, Fatos, Kvien, Tore K., Rotar, Ziga, Santos, Maria Jose, Iannone, Florenzo, Hokkanen, Anna-Mari, Gudbjornsson, Bjorn, Askling, Johan, Ionescu, Ruxandra, Nissen, Michael J., Pavelka, Karel, Sanchez-Piedra, Carlos, Akar, Servet, Sexton, Joseph, Tomsic, Matija, Santos, Helena, Sebastiani, Marco, Österlund, Jenny, Geirsson, Arni Jon, Macfarlane, Gary, van der Horst-Bruinsma, Irene, Georgiadis, Stylianos, Brahe, Cecilie Heegaard, Ørnbjerg, Lykke Midtbøll, Hetland, Merete Lund, Østergaard, Mikkel

“…© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objectives: To…”
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Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries by Glintborg, B, Lindström, U, Aaltonen, K, Kristianslund, EK, Gudbjornsson, B, Chatzidionysiou, K, Askling, J, Nordström, D, Hetland, ML, Di Giuseppe, D, Dreyer, L, Kristensen, LE, Jørgensen, TS, Eklund, K, Grondal, G, Ernestam, S, Joensuu, J, Törmänen, MRK, Skydsgaard, H, Hagfors, J, Kvien, TK, Lie, E, Fagerli, K, Geirsson, AJ, Jonsson, H, Provan, SA, Krogh, NS, Jacobsson, LTH

“…Objectives: Large-scale observational cohorts may be used to study the effectiveness and rare side effects of biological disease-modifying anti-rheumatic drugs…”
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Comparing patient-reported outcomes entered at home versus at hospital, and testing touch screens for initial recruitment to scientific trials in arthritis patients (vol 48, pg 178, 2019) by Glintborg, B, Lindstrom, U, Aaltonen, K, Kristianslund, E, Gudbjornsson, B, Chatzidionysiou, K, Askling, J, Nordstrom, D, Hetland, M, Di Giuseppe, D, Dreyer, L, Kristensen, LE, Jorgensen, TS, Eklund, K, Grondal, G, Ernestam, S, Joensuu, J, Tormanen, MEK, Skydsgaard, H, Hagfors, J, Kvien, TK, Lie, E, Fagerli, K, Geirsson, AJ, Jonsson, H, Provan, SA, Krogh, NS, Jacobsson, LTH

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Genetic variants associated with platelet count are predictive of human disease and physiological markers by Mikaelsdottir, Evgenia, Thorleifsson, Gudmar, Stefansdottir, Lilja, Halldorsson, Gisli, Sigurdsson, Jon K., Lund, Sigrun H., Tragante, Vinicius, Melsted, Pall, Rognvaldsson, Solvi, Norland, Kristjan, Helgadottir, Anna, Magnusson, Magnus K., Ragnarsson, Gunnar B., Kristinsson, Sigurdur Y., Reykdal, Sigrun, Vidarsson, Brynjar, Gudmundsdottir, Ingibjorg J., Olafsson, Isleifur, Onundarson, Pall T., Sigurdardottir, Olof, Sigurdsson, Emil L., Grondal, Gerdur, Geirsson, Arni J., Geirsson, Gudmundur, Gudmundsson, Julius, Holm, Hilma, Saevarsdottir, Saedis, Jonsdottir, Ingileif, Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari

“…Platelets play an important role in hemostasis and other aspects of vascular biology. We conducted a meta-analysis of platelet count GWAS using data on 536,974…”
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Low starting dosage of infliximab with possible escalating dosage in psoriatic arthritis gives the same treatment results as standard dosage of adalimumab or etanercept: results from the nationwide Icelandic ICEBIO registry by Gudbjornsson, Bjorn, Geirsson, Arni Jon, Krogh, Niels Steen

“…To explore differences in response to a low dosage regimen of infliximab with an escalating dosage in comparison to a standard dosage of etanercept and…”
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Treatment retention of infliximab and etanercept originators versus their corresponding biosimilars: Nordic collaborative observational study of 2334 biologics naïve patients with spondyloarthritis by Lindström, Ulf, Glintborg, Bente, Di Giuseppe, Daniela, Nordström, Dan, Aarrestad Provan, Sella, Gudbjornsson, Bjorn, Askling, Johan, Lund Hetland, Merete, Aaltonen, Kalle, Krogh, Niels Steen, Geirsson, Arni Jon, Jacobsson, Lennart T H

“…ObjectiveAlthough clinical trials support equivalence of originator products and biosimilars for etanercept and infliximab, real-world studies among…”
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6 and 12-month Drug Retention Rates and Treatment Outcomes in 941 Patients with Axial Spondyloarthritis Treated with Secukinumab in Routine Clinical Practice in 12 European Countries in the EuroSpA Research Collaboration Network by Michelsen, B, Askling, J, Codreanu, C, Mann, H, Loft, AG, Pombo-Suarez, M, Rotar, Z, Kvien, T, Santos, MJ, Hokkanen, AM, Lannone, F, Gudbjornsson, B, Onen, F, Jacobsson, L, Ionescu, R, Pavelka, K, Sanchez-Piedra, C, Tomsic, M, Sexton, J, Santos, H, Osterlund, J, Cauli, A, Geirsson, AJ, Akar, S, Ciurea, A, Jones, G, van der Horst-Bruinsma, I, Brahe, CH, Georgiadis, S, Ornbjerg, LM, Ostergaard, M, Hetland, ML

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Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations by Olafsson, Sigurgeir, Stridh, Pernilla, Bos, Steffan Daniël, Ingason, Andres, Euesden, Jack, Sulem, Patrick, Thorleifsson, Gudmar, Gustafsson, Omar, Johannesson, Ari, Geirsson, Arni J., Thorsson, Arni V., Sigurgeirsson, Bardur, Ludviksson, Bjorn Runar, Olafsson, Elias, Kristjansdottir, Helga, Jonasson, Jon G., Olafsson, Jon Hjaltalin, Orvar, Kjartan B., Benediktsson, Rafn, Bjarnason, Ragnar, Kristjansdottir, Sjofn, Gislason, Thorarinn, Valdimarsson, Trausti, Mikaelsdottir, Evgenia, Sigurdsson, Snaevar, Jonsson, Stefan, Rafnar, Thorunn, Aarsland, Dag, Djurovic, Srdjan, Fladby, Tormod, Knudsen, Gun Peggy, Celius, Elisabeth G., Myhr, Kjell-Morten, Grondal, Gerdur, Steinsson, Kristjan, Valdimarsson, Helgi, Bjornsson, Sigurdur, Bjornsdottir, Unnur S., Bjornsson, Einar S, Nilsson, Bjorn, Andreassen, Ole A., Alfredsson, Lars, Hillert, Jan, Kockum, Ingrid Skelton, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Hreinn, Hjaltason, Haukur, Harbo, Hanne F., Olsson, Tomas, Jonsdottir, Ingileif, Stefansson, Kari

“…A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198…”
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Does Discordance Between Baseline Patient's and Evaluator's Global Assessment of Disease Activity Impact Retention and Remission Rates of a First TNF Inhibitor in Patients with Axial Spondyloarthritis? Data from the EuroSpA Research Collaboration Network by Michelsen, B, Ornbjerg, LM, Loft, AG, Kvien, T, Ciurea, A, Mann, H, Eklund, KK, Yazici, A, Santos, MJ, Askling, J, Rotar, Z, Gudbjornsson, B, Pombo-Suarez, M, Codreanu, C, van der Horst-Bruinsma, I, Kristianslund, E, Nissen, MJ, Pavelka, K, Trokovic, N, Inanc, N, Vieira-Sousa, E, DiGuiseppe, D, Tomsic, M, Geirsson, AJ, Ionescu, R, van de Sande, M, Iannone, F, Sanchez-Piedra, C, Jones, G, Hyldstrup, L, Hetland, ML, Ostergaard, M

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Predicting ASDAS Inactive Disease After 6 Months of TNFi Treatment in Bio-Naive Axial Spondyloarthritis Patients Treated in Clinical Practice - Results from the EuroSpA Collaboration by Ornbjerg, LM, Georgiadis, S, Lindstrom, U, Loft, AG, Ciurea, A, Mann, H, Akkoc, N, Iannone, F, Kristianslund, E, Hokkanen, AM, Santos, MJ, Codreanu, C, Sanchez-Piedra, C, Tomsic, M, Gudbjornsson, B, van der Horst-Bruinsma, I, Askling, J, Nissen, MJ, Pavelka, K, Gunduz, O, Atzeni, F, Sexton, J, Nordstrom, D, Santos, H, Ionescu, R, Pombo-Suarez, M, Rotar, Z, Geirsson, AJ, van de Sande, M, Macfarlane, G, Michelsen, B, Hetland, ML, Ostergaard, M

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Patient Reported Outcomes over Time in 25,988 Axial Spondyloarthritis Patients Initiating Treatment with 1st, 2nd or 3rd TNF Inhibitor in Clinical Practice - Is PRO Remission Achieved? Results from the EuroSpA Collaboration by Ornbjerg, LM, Askling, J, Loft, AG, Nissen, MJ, Mann, H, Direskeneli, H, Iannone, F, Sexton, J, Nordstrom, D, Santos, MJ, Codreanu, C, Pombo-Suarez, M, Rotar, Z, Gudbjornsson, B, Van der Horst-Bruinsma, I, Lindstrom, U, Ciurea, A, Pavelka, K, Yilmaz, N, Gremese, E, Kristianslund, E, Hokkanen, AM, Barcelos, A, Ionescu, R, Sanchez-Piedra, C, Tomsic, M, Geirsson, AJ, van de Sande, M, Macfarlane, G, Brahe, CH, Hetland, ML, Ostergaard, M

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