Search Results - "Geiger, Lena S."

Dynamic brain network reconfiguration as a potential schizophrenia genetic risk mechanism modulated by NMDA receptor function by Braun, Urs, Schäfer, Axel, Bassett, Danielle S., Rausch, Franziska, Schweiger, Janina I., Bilek, Edda, Erk, Susanne, Romanczuk-Seiferth, Nina, Grimm, Oliver, Geiger, Lena S., Haddad, Leila, Otto, Kristina, Mohnke, Sebastian, Heinz, Andreas, Zink, Mathias, Walter, Henrik, Schwarz, Emanuel, Meyer-Lindenberg, Andreas, Tost, Heike

“…Schizophrenia is increasingly recognized as a disorder of distributed neural dynamics, but the molecular and genetic contributions are poorly understood…”
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Multiparametric mapping of white matter microstructure in catatonia by Wasserthal, Jakob, Maier-Hein, Klaus H, Neher, Peter F, Northoff, Georg, Kubera, Katharina M, Fritze, Stefan, Harneit, Anais, Geiger, Lena S, Tost, Heike, Wolf, Robert C, Hirjak, Dusan

“…Catatonia is characterized by motor, affective and behavioral abnormalities. To date, the specific role of white matter (WM) abnormalities in schizophrenia…”
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Generative network models of altered structural brain connectivity in schizophrenia by Zhang, Xiaolong, Braun, Urs, Harneit, Anais, Zang, Zhenxiang, Geiger, Lena S., Betzel, Richard F., Chen, Junfang, Schweiger, Janina I., Schwarz, Kristina, Reinwald, Jonathan Rochus, Fritze, Stefan, Witt, Stephanie, Rietschel, Marcella, Nöthen, Markus M., Degenhardt, Franziska, Schwarz, Emanuel, Hirjak, Dusan, Meyer-Lindenberg, Andreas, Bassett, Danielle S., Tost, Heike

“…•Structural brain networks can be modeled as a trade-off between wiring cost and topological features.•Schizophrenia patients show lower spatial constraints…”
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Novelty modulates human striatal activation and prefrontal–striatal effective connectivity during working memory encoding by Geiger, Lena S., Moessnang, Carolin, Schäfer, Axel, Zang, Zhenxiang, Zangl, Maria, Cao, Hengyi, van Raalten, Tamar R., Meyer-Lindenberg, Andreas, Tost, Heike

“…The functional role of the basal ganglia (BG) in the gating of suitable motor responses to the cortex is well established. Growing evidence supports an…”
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Resting-state brain network features associated with short-term skill learning ability in humans and the influence of N -methyl- d -aspartate receptor antagonism by Zang, Zhenxiang, Geiger, Lena S., Braun, Urs, Cao, Hengyi, Zangl, Maria, Schäfer, Axel, Moessnang, Carolin, Ruf, Matthias, Reis, Janine, Schweiger, Janina I., Dixson, Luanna, Moscicki, Alexander, Schwarz, Emanuel, Meyer-Lindenberg, Andreas, Tost, Heike

“…Graph theoretical functional magnetic resonance imaging (fMRI) studies have demonstrated that brain networks reorganize significantly during motor skill…”
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A Neural Signature of Parkinsonism in Patients With Schizophrenia Spectrum Disorders: A Multimodal MRI Study Using Parallel ICA by Wolf, Robert C, Rashidi, Mahmoud, Fritze, Stefan, Kubera, Katharina M, Northoff, Georg, Sambataro, Fabio, Calhoun, Vince D, Geiger, Lena S, Tost, Heike, Hirjak, Dusan

“…Abstract Motor abnormalities in schizophrenia spectrum disorders (SSD) have increasingly attracted scientific interest in the past years. However, the neural…”
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Multimodal Associations of FKBP5 Methylation With Emotion-Regulatory Brain Circuits by Kremer, Thomas L., Chen, Junfang, Buhl, Anais, Berhe, Oksana, Bilek, Edda, Geiger, Lena S., Ma, Ren, Moessnang, Carolin, Reichert, Markus, Reinhard, Iris, Schwarz, Kristina, Schweiger, Janina I., Streit, Fabian, Witt, Stephanie H., Zang, Zhenxiang, Zhang, Xiaolong, Nöthen, Markus M., Rietschel, Marcella, Ebner-Priemer, Ulrich W., Schwarz, Emanuel, Meyer-Lindenberg, Andreas, Braun, Urs, Tost, Heike

“…Understanding the biological processes that underlie individual differences in emotion regulation and stress responsivity is a key challenge for translational…”
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Patterns of co‐altered brain structure and function underlying neurological soft signs in schizophrenia spectrum disorders by Hirjak, Dusan, Rashidi, Mahmoud, Fritze, Stefan, Bertolino, Alina L., Geiger, Lena S., Zang, Zhenxiang, Kubera, Katharina M., Schmitgen, Mike M., Sambataro, Fabio, Calhoun, Vince D., Weisbrod, Matthias, Tost, Heike, Wolf, Robert C.

“…Neurological soft signs (NSS) comprise a broad range of subtle neurological deficits and are considered to represent external markers of sensorimotor…”
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A neurodevelopmental signature of parkinsonism in schizophrenia by Wolf, Robert Christian, Kubera, Katharina M., Waddington, John L., Schmitgen, Mike M., Fritze, Stefan, Rashidi, Mahmoud, Thieme, Cristina E., Sambataro, Fabio, Geiger, Lena S., Tost, Heike, Hirjak, Dusan

“…While sensorimotor abnormalities in schizophrenia (SZ) are of increasing scientific interest, little is known about structural changes and their developmental…”
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Structure/function interrelationships and illness insight in patients with schizophrenia: a multimodal MRI data fusion study by Otte, Marie-Luise, Schmitgen, Mike M., Wolf, Nadine D., Kubera, Katharina M., Calhoun, Vince D., Fritze, Stefan, Geiger, Lena S., Tost, Heike, Seidl, Ulrich W., Meyer-Lindenberg, Andreas, Hirjak, Dusan, Wolf, Robert Christian

“…Illness insight in schizophrenia (SZ) has an important impact on treatment outcome, integration into society and can vary over the course of the disorder. To…”
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Cortical morphology and illness insight in patients with schizophrenia by Otte, Marie-Luise, Schmitgen, Mike M., Kubera, Katharina M., Wolf, Nadine D., Fritze, Stefan, Geiger, Lena S., Tost, Heike, Seidl, Ulrich W., Meyer-Lindenberg, Andreas, Hirjak, Dusan, Wolf, Robert C.

“…Insight into illness in schizophrenia (SZ) patients has a major impact on treatment adherence and outcome. Previous studies have linked distinct deviations of…”
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Structural alterations in brainstem, basal ganglia and thalamus associated with parkinsonism in schizophrenia spectrum disorders by Fritze, Stefan, Harneit, Anais, Waddington, John L., Kubera, Katharina M., Schmitgen, Mike M., Otte, Marie-Luise, Geiger, Lena S., Tost, Heike, Meyer-Lindenberg, Andreas, Wolf, Robert C., Hirjak, Dusan

“…The relative roles of brainstem, thalamus and striatum in parkinsonism in schizophrenia spectrum disorder (SSD) patients are largely unknown. To determine…”
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White matter microstructure alterations in cortico-striatal networks are associated with parkinsonism in schizophrenia spectrum disorders by Wasserthal, Jakob, Maier-Hein, Klaus H., Neher, Peter F., Wolf, Robert C., Northoff, Georg, Waddington, John L., Kubera, Katharina M., Fritze, Stefan, Harneit, Anais, Geiger, Lena S., Tost, Heike, Hirjak, Dusan

“…The specific role of white matter (WM) microstructure in parkinsonism among patients with schizophrenia spectrum disorders (SSD) is largely unknown. To…”
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MAOA‐VNTR genotype affects structural and functional connectivity in distributed brain networks by Harneit, Anais, Braun, Urs, Geiger, Lena S., Zang, Zhenxiang, Hakobjan, Marina, Donkelaar, Marjolein M. J., Schweiger, Janina I., Schwarz, Kristina, Gan, Gabriela, Erk, Susanne, Heinz, Andreas, Romanczuk‐Seiferth, Nina, Witt, Stephanie, Rietschel, Marcella, Walter, Henrik, Franke, Barbara, Meyer‐Lindenberg, Andreas, Tost, Heike

“…Previous studies have linked the low expression variant of a variable number of tandem repeat polymorphism in the monoamine oxidase A gene (MAOA‐L) to the risk…”
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The 5-HTTLPR Polymorphism Affects Network-Based Functional Connectivity in the Visual-Limbic System in Healthy Adults by Cao, Hengyi, Harneit, Anais, Walter, Henrik, Erk, Susanne, Braun, Urs, Moessnang, Carolin, Geiger, Lena S, Zang, Zhenxiang, Mohnke, Sebastian, Heinz, Andreas, Romanczuk-Seiferth, Nina, Mühleisen, Thomas, Mattheisen, Manuel, Witt, Stephanie H, Cichon, Sven, Nöthen, Markus M, Rietschel, Marcella, Meyer-Lindenberg, Andreas, Tost, Heike

“…The serotonin transporter-linked polymorphic region 5-HTTLPR is a key genetic regulator of 5-HTT expression in the human brain where the short allele S has…”
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Structural alterations of amygdala and hypothalamus contribute to catatonia by Fritze, Stefan, Brandt, Geva A, Kubera, Katharina M, Schmitgen, Mike M, Northoff, Georg, Geiger-Primo, Lena S, Tost, Heike, Meyer-Lindenberg, Andreas, Wolf, Robert C, Hirjak, Dusan

“…At present, current diagnostic criteria and systems neglect affective symptom expression in catatonia. This potentially serious omission could explain why…”
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Psychomotor slowing in schizophrenia is associated with cortical thinning of primary motor cortex: A three cohort structural magnetic resonance imaging study by Fritze, Stefan, Brandt, Geva A., Benedyk, Anastasia, Moldavski, Alexander, Geiger-Primo, Lena S., Andoh, Jamila, Volkmer, Sebastian, Braun, Urs, Kubera, Katharina M., Wolf, Robert C., von der Goltz, Christoph, Schwarz, Emanuel, Meyer-Lindenberg, Andreas, Tost, Heike, Hirjak, Dusan

“…•PANSS G#7 and TMT-B have a surrogate value for psychomotor slowing in SZ.•Primary motor cortex thinning contribute to psychomotor slowing in SZ.•Cortical…”
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