Search Results - "Gehring, R."

CONSENSUS REPORT: Recognizing non-melanoma skin cancer, including actinic keratosis, as an occupational disease - A Call to Action by John, S.M., Trakatelli, M., Gehring, R., Finlay, K., Fionda, C., Wittlich, M., Augustin, M., Hilpert, G., Barroso Dias, J. M., Ulrich, C., Pellacani, G.

“…Non‐melanoma skin cancer (NMSC) is by far the most common cancer diagnosed in westernized countries, and one of the few almost preventable cancers if detected…”
Get full text

Mathematical modeling and simulation in animal health - Part II: principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment by Lin, Z., Gehring, R., Mochel, J. P., Lavé, T., Riviere, J. E.

“…This review provides a tutorial for individuals interested in quantitative veterinary pharmacology and toxicology and offers a basis for establishing…”
Get full text

A systematic review and meta-analysis of human population studies on the association between exposure to toxic environmental chemicals and left ventricular dysfunction (LVD) by Donzelli, G., Sera, F., Morales, M.A., Vozzi, F., Roos, T., Schaffert, A., Paparella, M., Murugadoss, S., Mertens, B., Gehring, R., Linzalone, N.

“…Exposure to environmental chemicals has been associated with an elevated risk of heart failure (HF). However, the impact on early markers of HF, such as left…”
Get full text

Improved protection of outdoor workers from solar ultraviolet radiation: position statement by John, S.M., Garbe, C., French, L.E., Takala, J., Yared, W., Cardone, A., Gehring, R., Spahn, A., Stratigos, A.

“…The vast majority of non‐melanoma skin cancer (NMSC) is attributable to excessive exposure to ultraviolet radiation (UVR). Outdoor workers are exposed to an…”
Get full text

Hot topic: Early postpartum treatment of commercial dairy cows with nonsteroidal antiinflammatory drugs increases whole-lactation milk yield by Carpenter, A J, Ylioja, C M, Vargas, C F, Mamedova, L K, Mendonça, L G, Coetzee, J F, Hollis, L C, Gehring, R, Bradford, B J

“…Previous research has shown that postpartum administration of the nonsteroidal antiinflammatory drug (NSAID) sodium salicylate can increase 305-d milk yield in…”
Get more information

Impact of carprofen administration on stress and nociception responses of calves to cautery dehorning by Stock, M L, Barth, L A, Van Engen, N K, Millman, S T, Gehring, R, Wang, C, Voris, E A, Wulf, L W, Labeur, Léa, Hsu, W H, Coetzee, J F

“…The objective of this study was to investigate the effects of carprofen administered immediately before cautery dehorning on nociception and stress. Forty…”
Get full text

Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed‐effects to characterize and quantify variability in drug pharmacokinetics by Bon, C., Toutain, P. L., Concordet, D., Gehring, R., Martin‐Jimenez, T., Smith, J., Pelligand, L., Martinez, M., Whittem, T., Riviere, J. E., Mochel, J. P.

“…A common feature of human and veterinary pharmacokinetics is the importance of identifying and quantifying the key determinants of between‐patient variability…”
Get full text

Evaluation of PEG-L-asparaginase in asparagine suppression and anti-drug antibody development in healthy Beagle dogs: A multi-phase preclinical study by Feenstra, L.R., Gehring, R., van Geijlswijk, I.M., König, T., Prinsen, H.C.M.T., Vandemeulebroecke, K., Lammens, T., Krupa, A., Teske, E.

“…L-asparaginase is a frequently used drug in the treatment of canine malignant lymphoma. Since production and availability of native E. coli-derived…”
Get full text

Bioavailability of suppository acetaminophen in healthy and hospitalized ill dogs by Sikina, E. R., Bach, J. F., Lin, Z., Gehring, R., KuKanich, B.

“…To determine the plasma pharmacokinetics of suppository acetaminophen (APAP) in healthy dogs and clinically ill dogs. This prospective study used six healthy…”
Get full text

The effects of firocoxib on cautery disbudding pain and stress responses in preweaned dairy calves by Stock, M L, Millman, S T, Barth, L A, Van Engen, N K, Hsu, W H, Wang, C, Gehring, R, Parsons, R L, Coetzee, J F

“…Perioperative analgesic effects of oral firocoxib following cautery disbudding were investigated in preweaned calves. Twenty Holstein calves approximately 4 to…”
Get more information

Pharmacokinetics and electrophysiological effects of sotalol hydrochloride in horses by Broux, B., De Clercq, D., Decloedt, A., Vera, L., Devreese, M., Gehring, R., Croubels, S., Loon, G.

“…Summary Background Arrhythmias in horses may require long‐term anti‐arrhythmic therapy. Unfortunately, oral anti‐arrhythmic drugs for use in horses are…”
Get full text

Impact of oral meloxicam administered alone or in combination with gabapentin on experimentally induced lameness in beef calves by Coetzee, J F, Mosher, R A, Anderson, D E, Robert, B, Kohake, L E, Gehring, R, White, B J, Kukanich, B, Wang, C

“…This study examined the pharmacokinetics and analgesic effect of oral meloxicam (MEL) administered alone or in combination with gabapentin (GABA) in an…”
Get full text

A study to examine the relationship between metritis severity and depletion of oxytetracycline in plasma and milk after intrauterine infusion by Gorden, P J, Ydstie, J A, Kleinhenz, M D, Wulf, L W, Gehring, R, Lee, C J, Wang, C, Coetzee, J F

“…Metritis is a frequent problem in postpartum dairy cows. Intrauterine therapy with the antimicrobial oxytetracycline (OTC) is often used, although this therapy…”
Get more information

Comparative plasma and interstitial fluid pharmacokinetics of flunixin meglumine and ceftiofur hydrochloride following individual and co‐administration in dairy cows by Gorden, P. J., Kleinhenz, M. D., Wulf, L. W., Rajewski, S. J., Wang, C., Gehring, R., Coetzee, J. F.

“…Ceftiofur (CEF) and flunixin meglumine (FLU) are two drugs approved for use in beef and dairy cattle that are frequently used in combination for many diseases…”
Get full text

Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle by DeDonder, K. D., Apley, M. D., Li, M., Gehring, R., Harhay, D. M., Lubbers, B. V., White, B. J., Capik, S. F., KuKanich, B., Riviere, J. E., Tessman, R. K.

“…The objectives of this study were to determine (i) whether an association exists between individual pharmacokinetic parameters and treatment outcome when…”
Get full text

Comparison of milk and plasma pharmacokinetics of meloxicam in postpartum versus mid‐lactation Holstein cows by Gorden, P. J., Burchard, M., Ydstie, J. A., Kleinhenz, M. D., Wulf, L. W., Rajewski, S. J., Wang, C., Gehring, R., Mochel, J. P., Coetzee, J. F.

“…The objective of this study reported here was determine whether differences occurred in meloxicam pharmacokinetics between postpartum cows and mid‐lactation…”
Get full text

Interspecies allometric meta-analysis of the comparative pharmacokinetics of 85 drugs across veterinary and laboratory animal species by Huang, Q., Gehring, R., Tell, L. A., Li, M., Riviere, J. E.

“…Allometric scaling is widely used for the determination of first dosage regimen and the interpolation or extrapolation of pharmacokinetic parameters across…”
Get full text

Automation and applications of the tolerance limit method in estimating meat withdrawal periods for veterinary drugs by Udiani, O., Mason, S., Smith, G., Mzyk, D., Gehring, R., Tell, L., Riviere, J.E., Baynes, R.E.

“…•A program was written to streamline the US FDA Tolerance Limit Method calculation.•The program was given data analysis tools according to FDA guidance.•The…”
Get full text

The effects of titanium dioxide coatings on light-derived heating and transdermal heat transfer in bovine skin by Bartle, S. J., Thomson, D.U., Gehring, R., van der Merwe, D.

“…The effects of titanium dioxide coatings of bovine hides on light absorption and transdermal transfer of light-derived heat were investigated. Four hair-on rug…”
Get full text

Assessing product bioequivalence for extended‐release formulations and drugs with long half‐lives by GEHRING, R, MARTINEZ, M

“…Gehring, R., Martinez, M. Assessing product bioequivalence for extended‐release formulations and drugs with long half‐lives. J. vet. Pharmacol. Therap.35…”
Get full text