Search Results - "Geha, R M"

Substrate and Inhibitor Specificities for Human Monoamine Oxidase A and B Are Influenced by a Single Amino Acid by Geha, Rani Maurice, Rebrin, Igor, Chen, Kevin, Shih, Jean Chen

“…Monoamine oxidase (MAO) is responsible for the oxidation of biogenic and dietary amines. It exists as two isoforms, A and B, which have a 70% amino acid…”
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Determination of regions important for monoamine oxidase (MAO) A and B substrate and inhibitor selectivities by Shih, J C, Chen, K, Geha, R M

“…MAO-A and -B are defined by their substrate and inhibitor preferences. To determine which regions of the isoenzymes confer these preferences, we have…”
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Analysis of Conserved Active Site Residues in Monoamine Oxidase A and B and Their Three-dimensional Molecular Modeling by Geha, Rani Maurice, Chen, Kevin, Wouters, Johan, Ooms, Frédéric, Shih, Jean Chen

“…Monoamine oxidase (MAO) is a key enzyme responsible for the degradation of serotonin, norepinephrine, dopamine, and phenylethylamine. It is an outer membrane…”
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Effects of Carboxyl-terminal Truncations on the Activity and Solubility of Human Monoamine Oxidase B by Rebrin, I, Geha, R M, Chen, K, Shih, J C

“…Monoamine oxidase is an outer mitochondrial membrane protein that catalyzes the deamination of a number of neurotransmitters and dietary amines. To determine…”
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Phe(208) and Ile(199) in human monoamine oxidase A and B do not determine substrate and inhibitor specificities as in rat by Geha, R M, Chen, K, Shih, J C

“…It has been reported previously that reciprocally switching Phe(208) and Ile(199) in rat monoamine oxidase (MAO) A and B, respectively, was sufficient to…”
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Phe super(208) and Ile super(199) in Human Monoamine Oxidase A and B Do Not Determine Substrate and Inhibitor Specificities as in Rat by Geha, R M, Chen, K, Shih, J C

“…It has been reported previously that reciprocally switching Phe super(208) and Ile super(199) in rat monoamine oxidase (MAO) A and B, respectively, was…”
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Phe208 and Ile199 in Human Monoamine Oxidase A and B Do Not Determine Substrate and Inhibitor Specificities as in Rat by Geha, Rani Maurice, Chen, Kevin, Shih, Jean Chen

“…: It has been reported previously that reciprocally switching Phe208 and Ile199 in rat monoamine oxidase (MAO) A and B, respectively, was sufficient to switch…”
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