Search Results - "Geffner, J. R"

Effect of Nitric Oxide Donors on Oxygen-Dependent Cytotoxic Responses Mediated by Neutrophils by Andonegui, G, Trevani, A. S, Gamberale, R, Carreras, M. C, Poderoso, J. J, Giordano, M, Geffner, J. R

“…We analyzed the effect of nitric oxide (NO) on oxygen-dependent cytotoxic responses mediated by neutrophils against unopsonized erythrocytes using three NO…”
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Promotion of neutrophil apoptosis by TNF-alpha by Salamone, G, Giordano, M, Trevani, A S, Gamberale, R, Vermeulen, M, Schettinni, J, Geffner, J R

“…We examined the ability of TNF-alpha to modulate human neutrophil apoptosis. Neutrophils cultured with TNF-alpha alone undergo a low but significant increase…”
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Involvement of nitric oxide in the regulation of peripheral blood leukocyte counts by Geffner, J R, Trevani, A S, de D'Elia, I, Diament, M, Klein, D, Giordano, M

“…A role for nitric oxide (NO) in the regulation of blood leukocyte numbers was examined in BALB/c mice by employing the NO synthase inhibitor NG-nitro…”
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Nitric oxide synthase inhibitors enhance plasma levels of corticosterone and ACTH by Giordano, M, Vermeulen, M, Trevani, A S, Dran, G, Andonegui, G, Geffner, J R

“…The role of nitric oxide in the regulation of adrenal steroidogenesis was examined in BALB/c mice by employing the nitric oxide synthase inhibitors NG-nitro…”
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Extracellular acidic pH modulates oxygen‐dependent cytotoxic responses mediated by polymorphonuclear leucocytes and monocytes by GEFFNER, J. R., TREVANI, A. S., MINNUCCI, F., PALERMO, M. S., MAUGERI, N., ISTURIZ, M. A.

“…SUMMARY In the present study, we compared the ability of human neutrophils and monocytes to display oxygen‐dependent cytotoxic responses at pH 7.4 and 6.2. Our…”
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Activation of human platelets by immune complexes prepared with cationized human IgG by SCHATTNER, M, LAZZARI, M, TREVANI, A. S, MALCHIODI, E, KEMPFER, A. C, ISTURIZ, M. A, GEFFNER, J. R

“…The present study shows that the ability of soluble immune complexes (IC), prepared with human IgG and rabbit IgG antibodies against human IgG, to trigger…”
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Inhibition of human platelet activation by polymorphonuclear leukocytes by Schattner, Mirta A., Geffner, Jorge R., Isturiz, Martin A., Lazzari, Maria A.

“…1 The effect of unstimulated human polymorphonuclear leukocytes (PMNs) on platelet activation was examined. 2 Human platelet aggregation and adenosine…”
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Neutrophil erythrotoxicity induced by phorbol myristate acetate: mechanisms involved in neutrophil activation by Geffner, J R, Fontán, P A, Sordelli, D O, Isturiz, M A

“…The capacity of phorbol myristate acetate (PMA) to prime neutrophil cytotoxic responses induced by a second stimulus was investigated. Treatment of neutrophils…”
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Neutrophil cytotoxicity induced by immune complexes prepared with cationized antibodies by Geffner, J R, Trevani, A S, Malchiodi, E, Serebrinsky, G P, Isturiz, M A

“…Here we analyse the ability of soluble immune complexes (IC) prepared with cationized antibodies to induce cytotoxic responses mediated by neutrophils. While…”
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The role of reactive oxygen intermediates in nonspecific monocyte cytotoxicity induced by immune complexes by GEFFNER, J. R, GIORDANO, M, SEREBRINSKY, G, ISTURIZ, M

“…Normal human monocytes were induced to lyse nonsensitized target cells when triggered by precipitating immune complexes (IC) or soluble heat-aggregated IgG…”
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Different activation pathways involved in antibody-dependent and immune-complexes-triggered cytotoxicity mediated by neutrophils by GEFFNER, J. R, GIORDANO, M, SEREBRINSKY, G, ISTURIZ, M. A

“…We have shown previously that normal human neutrophils triggered by immune complexes displayed significant levels of cytotoxicity towards non-sensitized target…”
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Neutrophil-mediated cytotoxicity triggered by immune complexes: the role of reactive oxygen metabolites by GEFFNER, J. R, GIORDANO, M, PALERMO, M. S, PRAT, A, SEREBRINSKY, G. P, ISTURIZ, M. A

“…Normal human neutrophils triggered by precipitating immune complexes (IC), soluble IC (sIC) or heat-aggregated IgG (HAIgG) displayed low levels of cytotoxicity…”
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Neutrophil-mediated cytotoxicity induced by secretory IgA by Geffner, J R, Minnucci, F, Isturiz, M A

“…Normal human neutrophils triggered by secretory IgA (sIgA) displayed low levels of cytotoxicity towards non-sensitized red blood cells. Catalase completely…”
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Interferon-gamma enhances PAF-acether production by stimulated human polymorphonuclear leucocytes by Geffner, J R, Schattner, M A, Lazzari, M A, Isturiz, M A

“…Human polymorphonuclear leucocytes (PMN) stimulated with either immune complexes (IC), phorbol myristate acetate (PMA) or…”
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Neutrophil apoptosis induced by proteolytic enzymes by Trevani, A S, Andonegui, G, Giordano, M, Nociari, M, Fontán, P, Dran, G, Geffner, J R

“…In this study, we show that three proteolytic enzymes of different specificity-pronase, chymotrypsin, and trypsin-induced a dramatic stimulation of neutrophil…”
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Immune complexes inhibit apoptosis of chronic lymphocytic leukaemia B cells by Gamberale, Romina, Geffner, Jorge R., Trevani, Analía, Cherñavsky, Alejandra, Scolnik, Mariano, Arrosagaray, Guillermo, Sarmiento, Marcela, Giordano, Mirta

“…In the present study we examined the effect of immune complexes (IC) on the survival of chronic lymphocytic leukaemia (B‐CLL) B cells. Our results showed that…”
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Acidic pH increases the avidity of FcγR for immune complexes by López, D. H., Trevani, A. S., Salamone, G., Andonegui, G., Raiden, S., Giordano, M., Geffner, J. R.

“…Summary The interaction of immunoglobulin G (IgG) antibodies with FcγR constitutes a critical mechanism through which IgG antibody effector functions are…”
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Inhibition of human neutrophil apoptosis by platelets by Andonegui, G, Trevani, AS, Lopez, DH, Raiden, S, Giordano, M, Geffner, JR

“…In the absence of appropriate stimuli, polymorphonuclear neutrophils rapidly undergo characteristic changes indicative of programmed cell death or apoptosis…”
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Effect of nitric oxide donors on neutrophil responses induced by immune complexes by Andonegui, G, Trevani, A S, Dran, G, Geffner, J R

“…The present study characterizes the effect of two nitric oxide (NO) donors, S-nitrosoglutathione (GSNO) and sodium nitroprusside (SNP), on the ability of…”
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Effect of proteolytic enzymes on neutrophil FcγRII activity by TREVANI, A. S, ANDONEGUI, G. A, ISTURIZ, M. A, SCHATNER, M, SEREBRINSKY, G, GEFFNER, J. R

“…Previous studies have demonstrated that the treatment of neutrophils with proteolytic enzymes markedly reduces the expression of receptor III for the Fc…”
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