Search Results - "Geffeney, S"

Convergent Evolution of Tetrodotoxin-Resistant Sodium Channels in Predators and Prey by Toledo, G, Hanifin, C, Geffeney, S, Brodie, 3rd, E D

“…Convergent evolution of similar adaptive traits may arise from either common or disparate molecular and physiological mechanisms. The forces that determine the…”
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Mechanisms of Adaptation in a Predator-Prey Arms Race: TTX-Resistant Sodium Channels by Geffeney, Shana, Brodie, Edmund D., Ruben, Peter C., Brodie, Edmund D.

“…Populations of the garter snake Thamnophis sirtalis have evolved geographically variable resistance to tetrodotoxin (TTX) in a coevolutionary arms race with…”
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The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels by Geffeney, Shana L., Ruben, C.

“…Tetrodotoxin (TTX) is a highly specific blocker of voltage-gated sodium channels. The dissociation constant of block varies with different channel isoforms…”
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Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction by Geffeney, Shana L, Fujimoto, Esther, Brodie, Edmund D, Brodie, Edmund D, Ruben, Peter C

“…Understanding the molecular genetic basis of adaptations provides incomparable insight into the genetic mechanisms by which evolutionary diversification takes…”
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