Search Results - "Geens, M"

Genetic and epigenetic instability in human pluripotent stem cells by Nguyen, H T, Geens, M, Spits, C

“…There is an increasing body of evidence that human pluripotent stem cells (hPSCs) are prone to (epi)genetic instability during in vitro culture. This review…”
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Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL by Nguyen, H T, Geens, M, Mertzanidou, A, Jacobs, K, Heirman, C, Breckpot, K, Spits, C

“…Gain of 20q11.21 is a chromosomal abnormality that is recurrently found in human pluripotent stem cells and cancers, strongly suggesting that this mutation…”
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Sustained intrinsic WNT and BMP4 activation impairs hESC differentiation to definitive endoderm and drives the cells towards extra-embryonic mesoderm by Markouli, C., De Deckersberg, E. Couvreu, Dziedzicka, D., Regin, M., Franck, S., Keller, A., Gheldof, A., Geens, M., Sermon, K., Spits, C.

“…We identified a human embryonic stem cell subline that fails to respond to the differentiation cues needed to obtain endoderm derivatives, differentiating…”
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Totipotency and lineage segregation in the human embryo by De Paepe, C, Krivega, M, Cauffman, G, Geens, M, Van de Velde, H

“…During human preimplantation development the totipotent zygote divides and undergoes a number of changes that lead to the first lineage differentiation in the…”
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Two decades of embryonic stem cells: a historical overview by Eguizabal, C, Aran, B, Chuva de Sousa Lopes, S M, Geens, M, Heindryckx, B, Panula, S, Popovic, M, Vassena, R, Veiga, A

“…Abstract STUDY QUESTION How did the field of stem cell research develop in the years following the derivation of the first human embryonic stem cell (hESC)…”
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CAR expression in human embryos and hESC illustrates its role in pluripotency and tight junctions by Krivega, M, Geens, M, Van de Velde, H

“…Coxsackie virus and adenovirus receptor, CXADR (CAR), is present during embryogenesis and is involved in tissue regeneration, cancer and intercellular…”
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Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment by Markouli, C., Couvreu De Deckersberg, E., Regin, M., Nguyen, H.T., Zambelli, F., Keller, A., Dziedzicka, D., De Kock, J., Tilleman, L., Van Nieuwerburgh, F., Franceschini, L., Sermon, K., Geens, M., Spits, C.

“…Gain of 20q11.21 is one of the most common recurrent genomic aberrations in human pluripotent stem cells. Although it is known that overexpression of the…”
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Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture by Geens, M, Seriola, A, Barbé, L, Santalo, J, Veiga, A, Dée, K, Van Haute, L, Sermon, K, Spits, C

“…Does a preferential X chromosome inactivation (XCI) pattern exist in female human pluripotent stem cells (hPSCs) and does the pattern change during long-term…”
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The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells by Verloes, A., Spits, C., Vercammen, M., Geens, M., LeMaoult, J., Sermon, K., Coucke, W., Van de Velde, H.

“…The human leukocyte antigen (HLA)-G gene seems to play a pivotal role in maternal tolerance to the fetus. Little is known about HLA-G expression and its…”
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BMP4 plays a role in apoptosis during human preimplantation development by De Paepe, C., Aberkane, A., Dewandre, D., Essahib, W., Sermon, K., Geens, M., Verheyen, G., Tournaye, H., Van de Velde, H.

“…Comprehensive understanding of lineage differentiation and apoptosis processes is important to increase our knowledge of human preimplantation development in…”
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The role of the reprogramming method and pluripotency state in gamete differentiation from patient-specific human pluripotent stem cells by Mishra, S, Kacin, E, Stamatiadis, P, Franck, S, Van der Jeught, M, Mertes, H, Pennings, G, De Sutter, P, Sermon, K, Heindryckx, B, Geens, M

“…The derivation of gametes from patient-specific pluripotent stem cells may provide new perspectives for genetic parenthood for patients currently facing…”
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The efficiency of magnetic-activated cell sorting and fluorescence-activated cell sorting in the decontamination of testicular cell suspensions in cancer patients by Geens, M., Van de Velde, H., De Block, G., Goossens, E., Van Steirteghem, A., Tournaye, H.

“…BACKGROUND: Before clinical application, the feasibility and safety of autologous testicular stem cell transplantation should be explored. Apart from…”
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Cyclin E1 plays a key role in balancing between totipotency and differentiation in human embryonic cells by Krivega, M V, Geens, M, Heindryckx, B, Santos-Ribeiro, S, Tournaye, H, Van de Velde, H

“…We aimed to investigate if Cyclin E1 (CCNE1) plays a role in human embryogenesis, in particular during the early developmental stages characterized by a short…”
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Strategies for fertility preservation and restoration in the male by Geens, M

“…Patients faced with infertility due to spermatogonial stem cell loss have currently semen cryobanking as only option for fertility preservation. A growing…”
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Dietary inclusion of arabinoxylan oligosaccharides (AXOS) down regulates mucosal responses to a bacterial challenge in a piglet model by Niewold, Theo A., Schroyen, Martine, Geens, Marisa M., Verhelst, Roderick S.B., Courtin, Christophe M.

“…Dietary oligosaccharides can influence the composition of the gut microbiota, and some are suggested to improve host resistance against infections. The exact…”
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Susceptibility of piglets to enterotoxigenic Escherichia coli is not related to the expression of MUC13 and MUC20 by Schroyen, M., Stinckens, A., Verhelst, R., Geens, M., Cox, E., Niewold, T., Buys, N.

“…Summary Enterotoxigenic Escherichia coli (ETEC) is one of the most frequently isolated enteropathogens in production animals, especially pigs and calves…”
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Mouse spermatogonial stem cells obtain morphologic and functional characteristics of hematopoietic cells in vivo by Ning, Liang, Goossens, Ellen, Geens, Mieke, Van Saen, Dorien, Van Riet, Ivan, He, Dalin, Tournaye, Herman

“…BACKGROUND The aim of this study was to explore the plasticity and transdifferentiation potential of murine spermatogonial stem cells (SSCs) into hematopoietic…”
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DUX4 expression during osteogenic differentiation in mesenchymal stromal cells (MSCs) by de la Kethulle de Ryhove, L, Ansseau, E, Geens, M, Coppée, F, Sermon, K.D, Lagneaux, L, Belayew, A

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Optimizing culture conditions of a porcine epithelial cell line IPEC-J2 through a histological and physiological characterization by Geens, Marisa M., Niewold, Theo A.

“…The high similarity between pigs and humans makes pigs a good gastrointestinal (GI) model for humans. Recently an epithelial cell line originating from the…”
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Reply: Isolation of germ cells from leukaemic cells by Geens, M., Van de Velde, H., De Block, G., Goossens, E., Tournaye, H.

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