Search Results - "Geenen, Laurie W."
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The prevalence of pulmonary arterial hypertension before and after atrial septal defect closure at adult age: A systematic review
Published in The American heart journal (01-07-2018)“…The development or persistence of pulmonary arterial hypertension (PAH) after atrial septal defect (ASD) closure at adult age is associated with a poor…”
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Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
Published in Scientific reports (19-07-2022)“…Activation of the kynurenine pathway (KP) has been reported in patients with pulmonary arterial hypertension (PAH) undergoing PAH therapy. We aimed to…”
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Exploring the Prognostic Value of Novel Markers in Adults With a Systemic Right Ventricle
Published in Journal of the American Heart Association (03-09-2019)“…Background Adults with a systemic right ventricle (sRV) have a high risk of cardiac complications. This study aimed to identify prognostic markers in adults…”
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Blood Biomarkers Predict 10-Year Clinical Outcomes in Adult Patients With Congenital Heart Disease
Published in JACC. Advances (Online) (01-09-2024)“…The adult congenital heart disease (ACHD) population is growing and risk prediction is important to predict adverse outcome and consult patients during their…”
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Residual Pulmonary Hypertension more than 20 Years after Repair of Shunt Lesions
Published in Medicina (Kaunas, Lithuania) (16-06-2020)“…After successful surgical repair of a congenital shunt lesion, pulmonary hypertension (PH) often disappears. However, PH can persist long-term after the…”
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Blood and imaging biomarkers in the long-term follow-up of bicuspid aortic valve patients
Published in CJC open (Online) (01-01-2024)“…Bicuspid aortic valve (BAV) is a common congenital heart defect. Patients with BAV are at risk for long-term complications such as valve stenosis and…”
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Blood biomarkers in patients with bicuspid aortic valve disease
Published in Journal of cardiology (01-09-2020)“…•A substantial number of patients with bicuspid aortic valve (BAV) have elevated levels of NT-proBNP, hsTnT, and hs-CRP.•Higher NT-proBNP is associated with…”
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Evolution of blood biomarker levels following percutaneous atrial septal defect closure in adults
Published in International journal of cardiology. Heart & vasculature (01-10-2020)“…•A substantial number of adults with unrepaired ASD have elevated biomarker levels.•Percutaneous ASD closure in adults leads to acute changes in most biomarker…”
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Role of the electrocardiogram in the risk stratification of pulmonary hypertension
Published in Heart (British Cardiac Society) (01-02-2023)“…The prognosis of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) remains dismal. Better risk prediction is…”
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The prognostic value of various biomarkers in adults with pulmonary hypertension; a multi-biomarker approach
Published in The American heart journal (01-02-2019)“…This study aimed to investigate the prognostic value of six different biomarkers in patients with pulmonary hypertension (PH) and to explore whether a…”
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Prognostic value of soluble ST2 in adults with congenital heart disease
Published in Heart (British Cardiac Society) (01-07-2019)“…Soluble suppression of tumourigenicity-2 (sST2) is upregulated as response to myocardial stress and may be a potential biomarker for risk stratification in…”
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Novel biomarkers associated with thoracic aortic disease
Published in International journal of cardiology (01-05-2023)“…Biomarkers might help to improve diagnosis, surveillance and risk stratification of thoracic aortic disease (TAD). We explored the association between a broad…”
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Reply to letter to the editor: "Novel biomarkers associated with thoracic aortic disease"
Published in International journal of cardiology (01-10-2023)Get full text
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Heart rate: an accessible risk indicator in adult congenital heart disease
Published in Heart (British Cardiac Society) (01-03-2024)“…Higher resting heart rate has been described as a risk factor for adverse outcome in healthy individuals and cardiovascular patients. The aim of this study was…”
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Heart failure in congenital heart disease: management options and clinical challenges
Published in Expert review of cardiovascular therapy (02-08-2020)“…The population of adults with congenital heart disease (ACHD) is rapidly expanding and one of the major complications is heart failure. Timely diagnosis and…”
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Prognostic value of the electrocardiogram in patients with bicuspid aortic valve disease
Published in Journal of electrocardiology (01-09-2024)“…Identifying bicuspid aortic valve (BAV) patients at risk for cardiac events remains challenging and the role of the electrocardiogram (ECG) has not yet been…”
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Prognostic Value of Serial High-Sensitivity Troponin T Measurements in Adults With Congenital Heart Disease
Published in Canadian journal of cardiology (01-09-2020)“…Single high-sensitivity troponin T (hs-TnT) measurement is predictive of cardiac events in adults with congenital heart disease (ACHD). We aimed to study the…”
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The Prognostic Value of Soluble ST2 in Adults with Pulmonary Hypertension
Published in Journal of clinical medicine (20-09-2019)“…Soluble ST2 (sST2) is upregulated in response to myocardial stress and may serve as biomarker in adults with pulmonary hypertension (PH). This prospective…”
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Tuning and external validation of an adult congenital heart disease risk prediction model
Published in European heart journal. Quality of care & clinical outcomes (05-01-2022)“…Abstract Aims Adequate risk prediction can optimize the clinical management in adult congenital heart disease (ACHD). We aimed to update and subsequently…”
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Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension
Published in Journal of clinical medicine (25-04-2020)“…Exogenous melatonin has been reported to be beneficial in the treatment of pulmonary hypertension (PH) in animal models. Multiple mechanisms are involved, with…”
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