Search Results - "Gee, Christine E"

Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks by Bitzenhofer, Sebastian H, Ahlbeck, Joachim, Wolff, Amy, Wiegert, J. Simon, Gee, Christine E., Oertner, Thomas G., Hanganu-Opatz, Ileana L.

“…Coordinated activity patterns in the developing brain may contribute to the wiring of neuronal circuits underlying future behavioural requirements. However,…”
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Improved methods for marking active neuron populations by Moeyaert, Benjamien, Holt, Graham, Madangopal, Rajtarun, Perez-Alvarez, Alberto, Fearey, Brenna C., Trojanowski, Nicholas F., Ledderose, Julia, Zolnik, Timothy A., Das, Aniruddha, Patel, Davina, Brown, Timothy A., Sachdev, Robert N. S., Eickholt, Britta J., Larkum, Matthew E., Turrigiano, Gina G., Dana, Hod, Gee, Christine E., Oertner, Thomas G., Hope, Bruce T., Schreiter, Eric R.

“…Marking functionally distinct neuronal ensembles with high spatiotemporal resolution is a key challenge in systems neuroscience. We recently introduced…”
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Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain by Scheib, Ulrike, Broser, Matthias, Constantin, Oana M., Yang, Shang, Gao, Shiqiang, Mukherjee, Shatanik, Stehfest, Katja, Nagel, Georg, Gee, Christine E., Hegemann, Peter

“…The cyclic nucleotides cAMP and cGMP are important second messengers that orchestrate fundamental cellular responses. Here, we present the characterization of…”
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Sex-Dependent Regulation of Aromatase-Mediated Synaptic Plasticity in the Basolateral Amygdala by Bender, Roland A, Zhou, Lepu, Vierk, Ricardo, Brandt, Nicola, Keller, Alexander, Gee, Christine E, Schäfer, Michael K E, Rune, Gabriele M

“…The basolateral amygdala (BLA) integrates sensory input from cortical and subcortical regions, a function that requires marked synaptic plasticity. Here we…”
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Time-Dependent Image Restoration of Low-SNR Live-Cell Ca2 Fluorescence Microscopy Data by Woelk, Lena-Marie, Kannabiran , Sukanya A., Brock , Valerie J., Gee , Christine E., Lohr , Christian, Guse , Andreas H., Diercks , Björn-Philipp, Werner, René

“…Live-cell Ca2+ fluorescence microscopy is a cornerstone of cellular signaling analysis and imaging. The demand for high spatial and temporal imaging resolution…”
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Using Genetically Encoded Calcium Indicators to Study Astrocyte Physiology: A Field Guide by Lohr, Christian, Beiersdorfer, Antonia, Fischer, Timo, Hirnet, Daniela, Rotermund, Natalie, Sauer, Jessica, Schulz, Kristina, Gee, Christine E.

“…Ca 2+ imaging is the most frequently used technique to study glial cell physiology. While chemical Ca 2+ indicators served to visualize and measure changes in…”
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ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning by Lamothe-Molina, Paul J., Franzelin, Andreas, Beck, Lennart, Li, Dong, Auksutat, Lea, Fieblinger, Tim, Laprell, Laura, Alhbeck, Joachim, Gee, Christine E., Kneussel, Matthias, Engel, Andreas K., Hilgetag, Claus C., Morellini, Fabio, Oertner, Thomas G.

“…Mice display signs of fear when neurons that express cFos during fear conditioning are artificially reactivated. This finding gave rise to the notion that cFos…”
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A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis by Fearey, Brenna C., Binkle, Lars, Mensching, Daniel, Schulze, Christian, Lohr, Christian, Friese, Manuel A., Oertner, Thomas G., Gee, Christine E.

“…The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE)…”
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PACmn for improved optogenetic control of intracellular cAMP by Yang, Shang, Constantin, Oana M, Sachidanandan, Divya, Hofmann, Hannes, Kunz, Tobias C, Kozjak-Pavlovic, Vera, Oertner, Thomas G, Nagel, Georg, Kittel, Robert J, Gee, Christine E, Gao, Shiqiang

“…Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that transduces extracellular signals in virtually all eukaryotic cells. The soluble…”
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The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors by Mang, Géraldine M, Dürst, Thomas, Bürki, Hugo, Imobersteg, Stefan, Abramowski, Dorothee, Schuepbach, Edi, Hoyer, Daniel, Fendt, Markus, Gee, Christine E

“…Orexin peptides activate orexin 1 and orexin 2 receptors (OX(1)R and OX(2)R), regulate locomotion and sleep-wake. The dual OX(1)R/OX(2)R antagonist almorexant…”
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Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior by Gromova, Kira V., Muhia, Mary, Rothammer, Nicola, Gee, Christine E., Thies, Edda, Schaefer, Irina, Kress, Sabrina, Kilimann, Manfred W., Shevchuk, Olga, Oertner, Thomas G., Kneussel, Matthias

“…Autism spectrum disorders (ASDs) are associated with mutations affecting synaptic components, including GluN2B-NMDA receptors (NMDARs) and neurobeachin (NBEA)…”
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The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling by Gromova, Kira V., Thies, Edda, Janiesch, Philipp C., Lützenkirchen, Felix P., Zhu, Yipeng, Stajano, Daniele, Dürst, Céline D., Schweizer, Michaela, Konietzny, Anja, Mikhaylova, Marina, Gee, Christine E., Kneussel, Matthias

“…Homeostatic synaptic plasticity adjusts the strength of synapses to restrain neuronal activity within a physiological range. Postsynaptic guanylate…”
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Freeze-frame imaging of synaptic activity using SynTagMA by Perez-Alvarez, Alberto, Fearey, Brenna C., O’Toole, Ryan J., Yang, Wei, Arganda-Carreras, Ignacio, Lamothe-Molina, Paul J., Moeyaert, Benjamien, Mohr, Manuel A., Panzera, Lauren C., Schulze, Christian, Schreiter, Eric R., Wiegert, J. Simon, Gee, Christine E., Hoppa, Michael B., Oertner, Thomas G.

“…Information within the brain travels from neuron to neuron across billions of synapses. At any given moment, only a small subset of neurons and synapses are…”
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A2A adenosine receptor-driven cAMP signaling in olfactory bulb astrocytes is unaffected in experimental autoimmune encephalomyelitis by Wendlandt, Marina, Kürten, Alina J., Beiersdorfer, Antonia, Schubert, Charlotte, Samad-Yazdtchi, Kiana, Sauer, Jessica, Pinto, M. Carolina, Schulz, Kristina, Friese, Manuel A., Gee, Christine E., Hirnet, Daniela, Lohr, Christian

“…Introduction The cyclic nucleotide cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger, which is known to play an important…”
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Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior by Gee, Christine E., Peterlik, Daniel, Neuhäuser, Christoph, Bouhelal, Rochdi, Kaupmann, Klemens, Laue, Grit, Uschold-Schmidt, Nicole, Feuerbach, Dominik, Zimmermann, Kaspar, Ofner, Silvio, Cryan, John F., van der Putten, Herman, Fendt, Markus, Vranesic, Ivo, Glatthar, Ralf, Flor, Peter J.

“…The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. mGlu7 function has been…”
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Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition by Beck, Sebastian, Yu-Strzelczyk, Jing, Pauls, Dennis, Constantin, Oana M, Gee, Christine E, Ehmann, Nadine, Kittel, Robert J, Nagel, Georg, Gao, Shiqiang

“…Optogenetic manipulation of cells or living organisms became widely used in neuroscience following the introduction of the light-gated ion channel…”
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Single-Cell Electroporation of Neurons by Wiegert, J Simon, Gee, Christine E, Oertner, Thomas G

“…Single-cell electroporation allows the transfection of a small number of neurons in an organotypic culture with a single plasmid or a defined mixture of…”
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Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses by Mitlöhner, Jessica, Kaushik, Rahul, Niekisch, Hartmut, Blondiaux, Armand, Gee, Christine E, Happel, Max F K, Gundelfinger, Eckart, Dityatev, Alexander, Frischknecht, Renato, Seidenbecher, Constanze

“…In the brain, Hebbian-type and homeostatic forms of plasticity are affected by neuromodulators like dopamine (DA). Modifications of the perisynaptic…”
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Two Distinct Signaling Pathways Upregulate NMDA Receptor Responses via Two Distinct Metabotropic Glutamate Receptor Subtypes by Benquet, Pascal, Gee, Christine E, Gerber, Urs

“…Molecular processes regulating the gain of NMDA receptors modulate diverse physiological and pathological responses in the CNS. Group I metabotropic glutamate…”
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Preparation of Slice Cultures from Rodent Hippocampus by Gee, Christine E, Ohmert, Iris, Wiegert, J Simon, Oertner, Thomas G

“…This protocol describes the preparation of hippocampal slice cultures from rat or mouse pups using sterile conditions that do not require the use of…”
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