Search Results - "Geddo, Federica"
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Indole-3-Propionic Acid, a Gut Microbiota-Derived Tryptophan Metabolite, Promotes Endothelial Dysfunction Impairing Purinergic-Induced Nitric Oxide Release in Endothelial Cells
Published in International journal of molecular sciences (01-03-2024)“…Different gut microbiota-derived metabolites influence cardiovascular function, and, among all, the role of indole-3-propionic acid (IPA), from tryptophan…”
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Trimethylamine N-Oxide (TMAO) Impairs Purinergic Induced Intracellular Calcium Increase and Nitric Oxide Release in Endothelial Cells
Published in International journal of molecular sciences (02-04-2022)“…Trimethylamine N-oxide (TMAO) is a diet derived compound directly introduced through foodstuff, or endogenously synthesized from its precursors, primarily…”
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Protective Effects of ( E )-β-Caryophyllene (BCP) in Chronic Inflammation
Published in Nutrients (26-10-2020)“…( )-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant kingdom, where it contributes a unique aroma to essential oils and has a…”
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Modulation of Endothelial Function by TMAO, a Gut Microbiota-Derived Metabolite
Published in International journal of molecular sciences (01-03-2023)“…Endothelial function is essential in the maintenance of systemic homeostasis, whose modulation strictly depends on the proper activity of tissue-specific…”
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Squalene: More than a Step toward Sterols
Published in Antioxidants (02-08-2020)“…Squalene (SQ) is a natural triterpene widely distributed in nature. It is a metabolic intermediate of the sterol biosynthetic pathway and represents a possible…”
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Sex and Response to Cardioprotective Conditioning Maneuvers
Published in Frontiers in physiology (14-05-2021)“…Ischemic heart disease (IHD) is a multifactorial pathological condition strictly related to genetic, dietary, and lifestyle factors. Its morbidity and…”
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PipeNig ® -FL, a Fluid Extract of Black Pepper ( Piper Nigrum L.) with a High Standardized Content of Trans -β-Caryophyllene, Reduces Lipid Accumulation in 3T3-L1 Preadipocytes and Improves Glucose Uptake in C2C12 Myotubes
Published in Nutrients (15-11-2019)“…-β-caryophyllene (BCP) is a natural sesquiterpene hydrocarbon with several important pharmacological activities, including antioxidant, anti-inflammatory,…”
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Plant-Derived Trans -β-Caryophyllene Boosts Glucose Metabolism and ATP Synthesis in Skeletal Muscle Cells through Cannabinoid Type 2 Receptor Stimulation
Published in Nutrients (12-03-2021)“…Skeletal muscle plays a pivotal role in whole-body glucose metabolism, accounting for the highest percentage of glucose uptake and utilization in healthy…”
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Ischemic heart disease and cardioprotection: Focus on estrogenic hormonal setting and microvascular health
Published in Vascular pharmacology (01-12-2021)“…Ischemic Heart Disease (IHD) is a clinical condition characterized by insufficient blood flow to the cardiac tissue, and the consequent inappropriate oxygen…”
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Trimethylamine N-oxide (TMAO) impact on endothelial dysfunction: An in vitro study using bovine aortic endothelial cells
Published in Vascular pharmacology (01-10-2022)Get full text
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Improving endothelial health with food-derived H 2 S donors: an in vitro study with S -allyl cysteine and with a black-garlic extract enriched in sulfur-containing compounds
Published in Food & function (11-05-2023)“…A healthy vascular endothelium plays an essential role in modulating vascular tone by producing and releasing vasoactive factors such as nitric oxide (NO)…”
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P-278 - KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease
Published in Free radical biology & medicine (20-05-2018)“…KRIT1 is a disease gene responsible for Cerebral Cavernous Malformation (CCM), a major cerebrovascular disease of proven genetic origin affecting 0.3–0.5% of…”
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P-132 - Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations
Published in Free radical biology & medicine (20-05-2018)“…Cerebral Cavernous Malformation (CCM) is a major cerebrovascular disease with a prevalence of 0.3–0.5% in the general population and highly variable clinical…”
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