Search Results - "Geddes, J.W"

Protein oxidation in the brain in Alzheimer's disease by Aksenov, M.Y., Aksenova, M.V., Butterfield, D.A., Geddes, J.W., Markesbery, W.R.

“…In this study we used immunohistochemistry and two-dimensional fingerprinting of oxidatively modified proteins (two-dimensional Oxyblot) together to…”
Get full text

Fenbendazole improves pathological and functional recovery following traumatic spinal cord injury by Yu, C.G, Singh, R, Crowdus, C, Raza, K, Kincer, J, Geddes, J.W

“…Highlights • Fenbendazole improved pathological and functional outcomes following SCI in mice. • Fenbendazole disrupts microtubules and can impair B cell…”
Get full text

Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease by Guo, Qing, Fu, Weiming, Xie, Jun, Luo, Hong, Sells, Stephen F, Geddes, J.W, Bondada, Vimala, Rangnekar, Vivek M, Mattson, Mark P

“…Prostate apoptosis response-4 (Par-4) is a protein containing both a leucine zipper and a death domain that was isolated by differential screening for genes…”
Get full text

Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease by Cummings, B J, Su, J H, Geddes, J W, Van Nostrand, W E, Wagner, S L, Cunningham, D D, Cotman, C W

“…Using a monoclonal antibody raised against purified, native, human protease nexin-2/amyloid precursor protein, which recognizes an amino terminal epitope on…”
Get more information

Comparison of Neuropathologic Criteria for the Diagnosis of Alzheimer’s Disease by Geddes, J.W, Tekirian, T.L, Soultanian, N.S, Ashford, J.W, Davis, D.G, Markesbery, W.R

“…The National Institute on Aging and Reagan Institute (NIA-RI) criteria, and other neuropathologic criteria for Alzheimer’s disease (AD), were compared with the…”
Get full text

Elevated Phosphocholine and Phosphatidylcholine Following Rat Entorhinal Cortex Lesions by Geddes, J.W., Panchalingam, K., Keller, J.N., Pettegrew, J.W.

“…At early stages of Alzheimer’s disease, phosphomonoesters (PMEs) including phosphocholine (P-choline) are present at elevated levels. PMEs also are elevated in…”
Get full text

N-methyl-D-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease by Ułas, J, Brunner, L C, Geddes, J W, Choe, W, Cotman, C W

“…The various ligand binding sites of the N-methyl-D-aspartate receptor complex in the hippocampal formation and parahippocampal gyrus of Alzheimer's disease…”
Get more information

Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker by Geddes, J W, Hess, E J, Hart, R A, Kesslak, J P, Cotman, C W, Wilson, M C

“…Synaptosomal-associated protein, 25 kD, (SNAP-25) is a novel protein containing a possible transition metal binding site and encoded by a neuronal-specific…”
Get more information

Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: non-N-methyl-D-aspartate receptors by Geddes, J W, Ułas, J, Brunner, L C, Choe, W, Cotman, C W

“…Quantitative receptor autoradiography was used to examine the density and distribution of [3H]kainic acid and…”
Get more information

[3H]TCP binding sites in Alzheimer's disease by Monaghan, D T, Geddes, J W, Yao, D, Chung, C, Cotman, C W

“…Quantitative autoradiography was used to determine the density and distribution of [3H]1-[1-(2-thienyl)-cyclohexyl]piperidine ([3H]TCP) binding sites in human…”
Get more information

N-methyl-D-aspartate receptors and Alzheimer's disease by Cotman, C W, Geddes, J W, Bridges, R J, Monaghan, D T

“…The results of several studies now suggest that the density of N-methyl-D-aspartate (NMDA) receptors is maintained in many Alzheimer's disease (AD) cases,…”
Get more information

Plasticity, pathology, and Alzheimer's disease by Geddes, J W, Cotman, C W

“…Much basic data support the notion that growth factors are important in the maintenance and repair of the CNS. Although local increases in growth factors might…”
Get more information