Search Results - "Gechtman, Z"
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Neuropilin-1 Binds Vascular Endothelial Growth Factor 165, Placenta Growth Factor-2, and Heparin via Its b1b2 Domain
Published in The Journal of biological chemistry (05-07-2002)“…Neuroplin-1 (NRP1), a receptor for vascular endothelial growth factor (VEGF) family members, has three distinct extracellular domains, a1a2, b1b2, and c. To…”
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Identification of a Natural Soluble Neuropilin-1 That Binds Vascular Endothelial Growth Factor: In vivo Expression and Antitumor Activity
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-2000)“…Neuropilin-1 (NRP1) is a 130-kDa transmembrane receptor for semaphorins, mediators of neuronal guidance, and for vascular endothelial growth factor 165…”
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Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor–positive breast carcinoma models
Published in Molecular cancer therapeutics (01-02-2006)“…We investigated the significance of erythropoietin receptor (EPOR) expression following treatment with recombinant human erythropoietin (rHuEPO; epoetin α) and…”
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The Shedding of Membrane-anchored Heparin-binding Epidermal-like Growth Factor Is Regulated by the Raf/Mitogen-activated Protein Kinase Cascade and by Cell Adhesion and Spreading
Published in The Journal of biological chemistry (01-10-1999)“…Heparin-binding epidermal-like growth factor (HB-EGF) is synthesized as a transmembrane precursor (HB-EGFTM). The addition of phorbol ester (PMA, phorbol…”
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Phosphorylation of vitronectin by casein kinase II. Identification of the sites and their promotion of cell adhesion and spreading
Published in The Journal of biological chemistry (18-09-1998)“…The cell adhesion protein vitronectin (Vn) was previously shown to be the major target in human blood for an extracellular protein kinase A, which is released…”
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The cluster of basic amino acids in vitronectin contributes to its binding of plasminogen activator inhibitor-1: evidence from thrombin-, elastase- and plasmin-cleaved vitronectins and anti-peptide antibodies
Published in Biochemical journal (15-07-1997)“…Derivatives of vitronectin obtained by specific cleavage at its cluster of basic amino acids with thrombin, elastase and plasmin are shown to have a decreased…”
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The PKA Phosphorylation of Vitronectin: Effect on Conformation and Function
Published in Archives of biochemistry and biophysics (15-01-2002)“…Vitronectin (Vn) stabilizes the inhibitory form of plasminogen activator inhibitor-1 (PAI-1), an important modulator of fibrinolysis. We have previously…”
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Involvement of protein phosphorylation in activation of Ca2+ efflux from sarcoplasmic reticulum
Published in Biochemical journal (15-05-1991)“…Preincubation of sarcoplasmic reticulum (SR) membranes with a combination of ATP and NaF resulted in inhibition of Ca2+ accumulation and stimulation of…”
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Phosphorylation of Vitronectin on Ser362 by Protein Kinase C Attenuates Its Cleavage by Plasmin
Published in European journal of biochemistry (15-01-1997)“…Vitronectin, found in the extracellular matrix and in circulating blood, has an important role in the control of plasminogen activation. It was shown to be the…”
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Synthetic peptides derived from the sequence around the plasmin cleavage site in vitronectin: Use in mapping the PAI-1 binding site
Published in FEBS letters (11-01-1993)“…A series of 8 peptides derived from the amino acid sequence accommodating the plasmin cleavage site in vitronectin were synthesized and used to map its binding…”
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Characterization of Ca(2+)-dependent endogenous phosphorylation of 160,000- and 150,000-Dalton proteins of sarcoplasmic reticulum
Published in Biochemical journal (15-05-1991)“…The 160 and 150 kDa proteins of sarcoplasmic reticulum (SR) are phosphorylated endogenously. The phosphorylation of both proteins has a marked requirement for…”
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Characterization of Ca2+-dependent endogenous phosphorylation of 160,000- and 150,000-Dalton proteins of sarcoplasmic reticulum
Published in Biochemical journal (15-05-1991)“…The 160 and 150 kDa proteins of sarcoplasmic reticulum (SR) are phosphorylated endogenously. The phosphorylation of both proteins has a marked requirement for…”
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13
Involvement of protein phosphorylation in activation of Ca super(2+) efflux from sarcoplasmic reticulum
Published in Biochemical journal (01-01-1991)“…Preincubation of sarcoplasmic reticulum (SR) membranes with a combination of ATP and NaF resulted in inhibition of Ca super(2+) accumulation and stimulation of…”
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Characterization of Ca super(2+)-dependent endogenous phosphorylation of 160,000- and 150,000-dalton proteins of sarcoplasmic reticulum
Published in Biochemical journal (01-01-1991)“…The 160 and 150 kDa proteins of sarcoplasmic reticulum (SR) are phosphorylated endogenously. The phosphorylation of both proteins has a marked requirement for…”
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