Search Results - "Gebhart, E."

Experimental Pellet Shatter Thresholds and Analysis of Shatter Tube Ejecta for Disruption Mitigation Cryogenic Pellets by Gebhart, T. E., Baylor, L. R., Meitner, S. J.

“…Mitigating disruptions is essential for the longevity of future large tokamak experimental devices and reactors. Currently, shattered pellet injection (SPI)…”
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Ring chromosomes in human neoplasias by Gebhart, E

“…Though reported from a wide variety of human neoplasias, ring chromosomes, in general, are a rare finding in these diseases. The majority were detected by…”
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Injection of high-speed solid D2 pellets using a “Direct-Line-of-Sight” (DLS) guide tube by Frattolillo, Antonio, Baylor, Larry R., Day, Christian, Gebhart, Trey E., Lang, Peter T., Meitner, Steven J., Migliori, Silvio, Ploeckl, Bernhard, Poggi, Fabrizio

“…•Core fueling of EU-DEMO tokamak requires pellet injection from the High Field Side.•Pellet speeds ≳ 1 km/s are necessary for efficient core fueling of reactor…”
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A Prototype High-Voltage Pulsed Power Supply for Control of the ITER Shattered Pellet Injection System Flyer Plate Valve by Ericson, M. N., Gebhart, T. E., Baylor, L. R., Frank, S. S., Nycz, A., Long, G. B., Warmack, R. J.

“…A high-voltage pulsed power supply (HVPPS) has been designed, prototyped, and tested for driving an eddy current actuated propellant valve for the…”
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Comparative genomic hybridization (CGH): ten years of substantial progress in human solid tumor molecular cytogenetics by Gebhart, E

“…Data from ten years of research using comparative genomic hybridization (CGH) for the detection of chromosomal alterations in human solid tumors are concisely…”
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Patterns of genomic imbalances in human solid tumors (Review) by Gebhart, E, Liehr, T

“…Based on comparative studies on CGH-detected genomic imbalances in head and neck squamous cell carcinomas and in ovarian tumors it was supposed that the…”
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Continuous intraventricular pressure monitoring for diagnosis of normal-pressure hydrocephalus by Pfisterer, W K, Aboul-Enein, F, Gebhart, E, Graf, M, Aichholzer, M, Mühlbauer, M

“…Normal-pressure hydrocephalus (NPH) syndrome is treatable by implantation of a cerebrospinal fluid (CSF) shunt. However, diagnosis of NPH by clinical and…”
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Are telomeres a specific target for mutagenic attack by cytostatics in neoplastic cells? by Wick, U, Gebhart, E

“…Damage to telomeres induced by cytostatic therapy theoretically could generate telomere shortening and, subsequently, induce an additional genomic instability…”
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Deployment of multiple shattered pellet injection systems in KSTAR by Park, SooHwan, Lee, KunSu, Baylor, Larry R., Meitner, Steven J., Lee, HyunMyung, Song, JaeIn, Gebhart, Trey E., Yun, SangWon, Kim, Jayhyun, Kim, KwangPyo, Park, KapRai, Yoon, SiWoo

“…•Shattered pellet injection (SPI) is of the most attractive way to mitigate the plasma disruption.•ITER has decided to adopt this technology for the DMS…”
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Design and Testing of a Prototype Eddy Current Actuated Valve for the ITER Shattered Pellet Injection System by Gebhart, T. E., Ericson, M. N., Meitner, S. J., Baylor, L. R., Gardner, W. L., Bigelow, T. S., Rasmussen, D. A.

“…Reliably mitigating disruptions is essential for ITER to meet its long-term operational research plan without damage to the in-vessel components. Currently,…”
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Studies on the action of mitomycin C and bleomycin on telomere lengths of human lymphocyte chromosomes by Wick, U, Gebhart, E

“…In order to address the problem of the action of cytostatics on chromosome ends, telomere length was measured in human lymphocyte cultures exposed to mitomycin…”
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The order of PNA-FISH-detected chromosomal telomere lengths in human T-cells is rather stable, even under the influence of strong mutagens by Wick, U, Gebhart, E

“…The nucleo-protein structure of an intact telomere protects each chromosome from being recognized as a break and subsequently being degraded. The DNA component…”
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Developing fuel sources for a steady-state multi-purpose pellet launching system by Lang, P.T., Baylor, L.R., Craciunescu, T., Gebhart, T.E., Meitner, S.J., Ploeckl, B.

“…Like for any power plant, refuelling will be one key issue in a future fusion reactor. It has to be safe and efficient; due to the operational principle, it…”
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Design of a Continuous Pellet Fueling System for Wendelstein 7-X by Meitner, Steven J., Baylor, L. R., Gebhart, T. E., Harris, J. H., Mcginnis, W. D., Bjorholm, T. P., Logan, K. G.

“…A continuous pellet fueling system (CPFS) is currently being designed at the Oak Ridge National Laboratory (ORNL) for the long pulse operation of the…”
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Comet-assay in combination with PNA-FISH detects mutagen-induced DNA damage and specific repeat sequences in the damaged DNA of transformed cells by Hovhannisyan, G, Rapp, A, Arutyunyan, R, Greulich, K O, Gebhart, E

“…The Comet-assay was applied to three transformed cell lines (HT1080, CCRF-CEM line and CHO) which were treated with the cytostatics bleomycin (BLM) or…”
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Oral squamous cell carcinomas are characterized by a rather uniform pattern of genomic imbalances detected by comparative genomic hybridisation by Wolff, E, Girod, S, Liehr, T, Vorderwülbecke, U, Ries, J, Steininger, H, Gebhart, E

“…Total genomic DNA sampled from 20 oral squamous cell carcinomas (SCCs) and from four SCC cell lines, was examined for genomic imbalances using comparative…”
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Impact of breech geometry and propellant flow on the release of large pellets for the ITER disruption mitigation system by Gebhart, T.E., Baylor, L.R., Dibon, M., Ericson, M.N., Felske, E.J., Frank, S.S., Gardner, W.L., Ghiozzi, A.G., Jachmich, S., Kruezi, U., Lehnen, M., Velez, D.A.

“…Abstract Studies have been performed on the release mechanism for large pellets using high pressure gas in a shattered pellet injector. Typically, pellets are…”
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Loss of 9p21 is embedded in a complex but consistent pattern of genomic imbalances in oral squamous cell carcinomas by Gebhart, E, Liehr, T, Wolff, E, Wiltfang, J, Koscielny, S, Ries, J

“…35 oral squamous cell carcinomas examined previously by comparative genomic hybridization (CGH) exhibited 5 up to 47 copy number alterations (CNAs). 13 of…”
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Solidification and Acceleration of Large Cryogenic Pellets Relevant for Plasma Disruption Mitigation by Combs, S. K., Meitner, S. J., Gebhart, T. E., Baylor, L. R., Caughman, J. B. O., Fehling, D. T., Foust, C. R., Ha, T., Lyttle, M. S., Fisher, J. T., Younkin, T. R.

“…The technology for producing, accelerating, and shattering large pellets (before injection into plasmas) for disruption mitigation has been under development…”
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Comparative analysis of imbalances in genomic DNA and mRNA expression levels in chondrosarcoma-derived cell line FSCP-1 by Schörle, C M, Verdorfer, I, Finger, F, Block, J, Gebhart, E, Aigner, T

“…Malignant cell transformation results from multiple biological alterations including chromosomal abnormalities, oncogene activation, loss of suppressor gene…”
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