Search Results - "Gebert, J. Thomas"
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Rotavirus induces intercellular calcium waves through ADP signaling
Published in Science (American Association for the Advancement of Science) (20-11-2020)“…Rotavirus causes severe diarrheal disease in children by broadly dysregulating intestinal homeostasis. However, the underlying mechanism(s) of…”
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Using Forward and Reverse Genetics to Understand Calcium Dysregulation in Enteric Viral Virulence
Published in The FASEB journal (01-05-2022)“…Acute gastroenteritis (AGE) remains the second leading cause of death among children under the age of 5 worldwide. AGE becomes fatal when pathogen‐associated…”
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Chronic pain in adolescence and internalizing mental health disorders: a nationally representative study
Published in Pain (Amsterdam) (01-06-2016)“…Chronic pain in childhood and adolescence has been shown to heighten the risk for depressive and anxiety disorders in specific samples in adulthood; however,…”
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Trends in opioid prescriptions among children and adolescents in the United States: a nationally representative study from 1996 to 2012
Published in Pain (Amsterdam) (01-05-2016)“…Prescription opioid misuse is a major public health concern in the United States, yet little is known about national prescription patterns. We aimed to assess…”
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Gastrointestinal organoids in the study of viral infections
Published in American journal of physiology: Gastrointestinal and liver physiology (01-01-2023)“…Viruses are among the most prevalent enteric pathogens. Although virologists historically relied on cell lines and animal models, human intestinal organoids…”
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Live-Cell Fluorescence Imaging for Virus-Host Interactions
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Recent technological advances in microscopy have facilitated novel approaches to investigate host-pathogen interactions. In particular, improvements in both…”
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Distribution of P2Y and P2X purinergic receptor expression within the intestine
Published in American journal of physiology: Gastrointestinal and liver physiology (01-02-2024)“…Nucleotides are potent extracellular signaling molecules during homeostasis, infection, and injury due to their ability to activate purinergic receptors. The…”
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Live Calcium Imaging of Virus-Infected Human Intestinal Organoid Monolayers Using Genetically Encoded Calcium Indicators
Published in Journal of visualized experiments (19-01-2024)“…Calcium signaling is an integral regulator of nearly every tissue. Within the intestinal epithelium, calcium is involved in the regulation of secretory…”
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Su1231 ROTAVIRUS INFECTION ELICITS HOST RESPONSES VIA P2Y1 PURINERGIC SIGNALING
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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