Search Results - "Gearing, AJ"

Characterisation of matrix metalloproteinases and the effects of a broad-spectrum inhibitor (BB-1101) in peripheral nerve regeneration by Demestre, M, Wells, G.M, Miller, K.M, Smith, K.J, Hughes, R.A.C, Gearing, A.J, Gregson, N.A

“…The effect of treatment with a broad-spectrum inhibitor (BB1101) of the matrix metalloproteinases (MMPs) on nerve regeneration and functional recovery after…”
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Circulating intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1) in human malignancies by BANKS, R. E, GEARING, A. J. H, HEMINGWAY, I. K, NORFOLK, D. R, PERREN, T. J, SELBY, P. J

“…Cellular adhesion molecules have been implicated in tumour progression and metastasis. This study examines for the first time the serum concentrations of…”
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Characterization of matrix metalloproteinases in denervated muscle by Demestre, M., Orth, M., Wells, G. M., Gearing, A. J., Hughes, R. A. C., Gregson, N. A.

“…In a nerve crush model of denervation, we examined muscle matrix metalloproteinase (MMP) expression, localization and activity. In normal muscle, MMP mRNA…”
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Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases by GAROFALO, A, CHIRIVI, R. G. S, GIAVAZZI, R, FOGLIENI, C, PIGOTT, R, MORTARNIN, R, MARTIN-PADURA, I, ANICHINI, A, GEARING, A. J, SANCHEZ-MADRID, F, DEJANA, E

“…We have previously reported that treatment with interleukin 1 (IL-1) induced the augmentation of lung tumor colonies by a human melanoma in nude mice. Here we…”
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Macrophage-inflammatory protein protects multipotent hematopoietic cells from the cytotoxic effects of hydroxyurea in vivo by Lord, BI, Dexter, TM, Clements, JM, Hunter, MA, Gearing, AJ

“…Macrophage inflammatory protein-1 alpha (MIP-1 alpha) has been assessed for its potential in vivo to protect hematopoietic progenitor cells from the cytotoxic…”
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Targeted lymph node immunization with simian immunodeficiency virus p27 antigen to elicit genital, rectal, and urinary immune responses in nonhuman primates by Lehner, T, Bergmeier, LA, Tao, L, Panagiotidi, C, Klavinskis, LS, Hussain, L, Ward, RG, Meyers, N, Adams, SE, Gearing, AJ

“…A s.c. route of immunization was developed in non-human primates, which targets the genitourinary-rectal associated lymphoid tissue. A vaccine consisting of…”
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Macrophage-Inflammatory Protein Protects Multipotent Hematopoietic Cells From the Cytotoxic Effects of Hydroxyurea In Vivo by Lord, B.l., Dexter, T.M., Clements, J.M., Hunter, M.A., Gearing, A.J.H.

“…Macrophage inflammatory protein-1 α (MIP-1α) has been assessed for its potential in vivo to protect hematopoietic progenitor cells from the cytotoxic effects…”
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Induction of HIV-specific cytotoxic T lymphocytes in vivo with hybrid HIV-1 V3:Ty-virus-like particles by Layton, GT, Harris, SJ, Gearing, AJ, Hill-Perkins, M, Cole, JS, Griffiths, JC, Burns, NR, Kingsman, AJ, Adams, SE

“…In general, it has proven difficult to induce CTL responses using simple proteins or peptides without resorting to specialized adjuvants. In this study we show…”
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Expression and cell distribution of the intercellular adhesion molecule, vascular cell adhesion molecule, endothelial leukocyte adhesion molecule, and endothelial cell adhesion molecule (CD31) in reactive human lymph nodes and in Hodgkin's disease by Ruco, LP, Pomponi, D, Pigott, R, Gearing, AJ, Baiocchini, A, Baroni, CD

“…The immunocytochemical expression of intercellular adhesion molecule (ICAM-1), vascular cell adhesion molecule (VCAM-1), endothelial leukocyte adhesion…”
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Effect of a Matrix Metalloproteinase Inhibitor (BB-1101) on Nerve Regeneration by DEMESTRE, MARIA, GREGSON, N. A., SMITH, K. J., MILLER, K. M., GEARING, A. J., HUGHES, R.A. C.

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Adhesion molecule expression in the lung: a comparison between normal and diffuse interstitial lung disease by Southcott, AM, Hemingway, I, Lorimer, S, Sugars, K, Hellewell, PG, Black, CM, Jeffery, PK, Gearing, AJ, Haskard, DO, du Bois, RM

“…Cellular adhesion molecules are crucial determinants of the migration of immune effector cells to the tissues. In chronic inflammatory diseases, upregulation…”
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Neutrophil chemoattractant and IL-1-like activity in samples from psoriatic skin lesions. Further characterization by Fincham, NJ, Camp, RD, Gearing, AJ, Bird, CR, Cunningham, FM

“…The IL-1-like neutrophil chemoattractant activity previously reported by us to be present in the stratum corneum of psoriatic skin lesions has now been…”
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Tissue distribution of very late activation antigens-1/6 and very late activation antigen ligands in the normal thymus and in thymoma by Ruco, LP, Paradiso, P, Pittiglio, M, Diodoro, MG, Gearing, AJ, Mainiero, F, Gismondi, A, Santoni, A, Baroni, CD

“…The expression of very late activation antigens (VLAs)-1/6 was correlated with that of the VLA ligands fibronectin, laminin, collagen, and vascular cell…”
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Elevated levels of GM-CSF and IL-1 in the serum, peritoneal and pleural cavities of GM-CSF transgenic mice by GEARING, A. J, METCALF, D, MOORE, J. G, NICOLA, N. A

“…Levels of granulocyte-macrophage colony-stimulating factor (GM-CSF) in the peritoneal and pleural cavity fluid of two lines of GM-CSF transgenic mice were…”
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