Search Results - "Geara, F B"

Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of local and regional control by Sanguineti, G, Geara, F B, Garden, A S, Tucker, S L, Ang, K K, Morrison, W H, Peters, L J

“…This retrospective study was conducted to review the results of treatment and to identify prognostic factors for local and regional control in a population of…”
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Fibroblast radiosensitivity versus acute and late normal skin responses in patients treated for breast cancer by Brock, W A, Tucker, S L, Geara, F B, Turesson, I, Wike, J, Nyman, J, Peters, L J

“…To determine if the radiosensitivity of normal human skin fibroblasts, measured in early passage cultures, is significantly correlated with the degree of acute…”
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Radiation therapy for malignant melanoma by Geara, F B, Ang, K K

“…Sufficient biologic and clinical evidence now exists to refute the longstanding dogma that melanomas are uniformly radiation resistant and hence radiation…”
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Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients by Geara, F B, Peters, L J, Ang, K K, Wike, J L, Brock, W A

“…This pilot study was undertaken to assess the relationship between in vitro radiosensitivity of different normal cell types and the type and severity of normal…”
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Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer by Ang, K K, Trotti, A, Brown, B W, Garden, A S, Foote, R L, Morrison, W H, Geara, F B, Klotch, D W, Goepfert, H, Peters, L J

“…A multi-institutional, prospective, randomized trial was undertaken in patients with advanced head-and-neck squamous cell carcinoma to address (1) the validity…”
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Factors influencing the development of lung fibrosis after chemoradiation for small cell carcinoma of the lung: evidence for inherent interindividual variation by Geara, F B, Komaki, R, Tucker, S L, Travis, E L, Cox, J D

“…Clinical observations often reveal individual differences in the severity of lung fibrosis after definitive radiation therapy for lung cancer. Recent…”
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Induction chemotherapy followed by radiotherapy versus radiotherapy alone in patients with advanced nasopharyngeal carcinoma : Results of a matched cohort study by GEARA, F. B, GLISSON, B. S, HONG, W. K, SANGUINETI, G, TUCKER, S. L, GARDEN, A. S, ANG, K. K, LIPPMAN, S. M, CLAYMAN, G. L, GOEPFERT, H, PETERS, L. J

“…Prospective randomized and retrospective studies on adjunctive chemotherapy in patients with advanced locoregional nasopharyngeal carcinoma have yielded…”
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MO‐G‐BRC‐01: Comparison of the Risk of Second Malignant Neoplasm in a Developed Country versus a Developing Country for a 13‐Year‐Old Girl Receiving Craniospinal Irradiation by Taddei, P J, Jalbout, W, Khater, N, Geara, F B, Mirkovic, D, Howell, R M, Zhang, R, Giebeler, A, Mahajan, A, Newhauser, W D

“…Purpose: Childhood cancer is a global health problem that affects nations of every socioeconomic status. The incidence of treatment‐induced second malignant…”
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Transrectal ultrasound for staging prostate carcinoma prior to radiation therapy : An evaluation based on disease outcome by LIEBROSS, R. H, POLLACK, A, LANKFORD, S. P, ZAGARS, G. K, VON ESCHENBACH, A. C, GEARA, F. B

“…Despite its subjectivity and inaccuracy, digital rectal examination (DRE) has a long history of well-documented prognostic significance in patients with…”
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Short duration neoadjuvant chemotherapy followed by radiotherapy for advanced carcinoma of the cervix: results and prognostic variables by Seoud, M, Geara, F B, Shamseddine, A, Salem, Z, Khalil, A

“…The value of neoadjuvant chemotherapy in squamous cell carcinomas of the cervix has not been proven. It has been suggested that the potential benefit of this…”
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The T classification of clinically localized prostate cancer. An appraisal based on disease outcome after radiation therapy by Zagars, G K, Geara, F B, Pollack, A, von Eschenbach, A C

“…This study was performed to evaluate the use of the 1992 International Union Against Cancer (UICC)/American Joint Committee on Cancer (AJCC) T categories for…”
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Comparison between normal tissue reactions and local tumor control in head and neck cancer patients treated by definitive radiotherapy by Geara, F B, Peters, L J, Ang, K K, Garden, A S, Tucker, S L, Levy, L B, Brown, B W

“…This study was conducted to test for the relationship between tumor and normal tissue radiosensitivity, by comparing local tumor control to the severity of…”
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SU‐E‐T‐276: Equivalent Dose in Children Receiving Craniospinal Irradiation with Photons in a Developing Country Or with Protons in a Developed Country by Taddei, PJ, Khater, N, Youssef, B, Jalbout, W, Howell, RM, Mahajan, A, Zhang, R, Mirkovic, D, Giebeler, A, Geara, FB, Newhauser, WD

“…Purpose: Childhood cancer survivors who were treated with craniospinal irradiation (CSI) have a high risk of radiogenic late effects, for example second…”
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Radiosensitivity measurement of keratinocytes and fibroblasts from radiotherapy patients by Geara, F B, Peters, L J, Ang, K K, Wike, J L, Brock, W A

“…Genetic diversity is believed to influence cellular radiosensitivity and individual variability in normal tissue reactions to radiotherapy. To measure normal…”
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Evidence of haplotype insufficiency in human cells containing a germline mutation in BRCA1 or BRCA2 by Buchholz, Thomas A., Wu, Xifeng, Hussain, Abu, Tucker, Susan L., Mills, Gordon B., Haffty, Bruce, Bergh, Sherry, Story, Michael, Geara, Fady B., Brock, William A.

“…The BRCA1 and BRCA2 gene products are thought to play important roles in the processing of DNA damage. To assess whether heterozygous mutations in these genes…”
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Influence of initial presentation on treatment outcome of clinically localized prostate cancer treated by definitive radiation therapy by Geara, F B, Zagars, G K, Pollack, A

“…The increasing proportion of early stage prostate cancer diagnosed by various early detection methods together with reports espousing watchful waiting as a…”
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Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of distant metastasis and survival by Geara, Fady B., Sanguineti, Giuseppe, Tucker, Susan L., Garden, Adam S., Ang, K.Kian, Morrison, William H., Peters, Lester J.

“…Purpose: This retrospective study was conducted to identify the prognostic factors for distant metastasis and survival in a population of 378 patients with…”
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How much could the radiotherapy dose be altered for individual patients based on a predictive assay of normal-tissue radiosensitivity? by Tucker, Susan L., Geara, Fady B., Peters, Lester J., Brock, William A.

“…Predictive assays are presently being developed to identify the patients at highest risk for developing severe late normal-tissue complications. If such…”
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Intrinsic radiosensitivity of normal human fibroblasts and lymphocytes after high- and low-dose-rate irradiation by GEARA, F. B, PETERS, L. J, ANG, K. K, WIKE, J. L, SIVON, S. S, GUTTENBERGER, R, CALLENDER, D. L, MALAISE, E. P, BROCK, W. A

“…The existence of heritable radiosensitivity syndromes and clinical observations in radiotherapy patients suggests that human cellular radiosensitivity differs…”
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Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation by Prithivirajsingh, Sheela, Story, Michael D, Bergh, Sherry A, Geara, Fady B, Kian Ang, K, Ismail, Sheikh M, Stevens, Craig W, Buchholz, Thomas A, Brock, William A

“…Point mutations and deletions in mitochondrial DNA (mtDNA) accumulate as a result of oxidative stress, including ionizing radiation. As a result, dysfunctional…”
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