Search Results - "Ge, Xudong"
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A novel, low-cost microfluidic device with an integrated filter for rapid, ultrasensitive, and high-throughput bioburden detection
Published in Scientific reports (26-07-2023)“…Rapid and accurate bioburden detection has become increasingly necessary for food, health, pharmaceutical and environmental applications. To detect bioburden…”
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Real‐time dissolved carbon dioxide monitoring I: Application of a novel in situ sensor for CO2 monitoring and control
Published in Biotechnology and bioengineering (01-04-2020)“…Dissolved carbon dioxide (dCO2) is a well‐known critical parameter in bioprocesses due to its significant impact on cell metabolism and on product quality…”
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Microwave induced thermally assisted solvent-based bonding of biodegradable thermoplastics: an eco-friendly rapid approach for fabrication of microfluidic devices and analyte detection
Published in Scientific reports (27-09-2022)“…There is an increasing interest in low-cost, facile and versatile thermoplastic bonding for microfluidic applications that can be easily transitioned from…”
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Real‐time dissolved carbon dioxide monitoring II: Surface aeration intensification for efficient CO2 removal in shake flasks and mini‐bioreactors leads to superior growth and recombinant protein yields
Published in Biotechnology and bioengineering (01-04-2020)“…Mass transfer is known to play a critical role in bioprocess performance and henceforth monitoring dissolved O2 (DO) and dissolved CO2 (dCO2) is of paramount…”
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A novel approach to noninvasive monitoring of dissolved carbon dioxide in small-scale cell culture processes
Published in Frontiers in bioengineering and biotechnology (06-09-2022)“…Disposable small-scale vessels are commonly used in cell culture studies in academia as well as early stages of bioprocess development. These types of research…”
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Real-time monitoring of shake flask fermentation and off gas using triple disposable noninvasive optical sensors
Published in Biotechnology progress (01-05-2012)“…Bioprocess development is a data‐driven process requiring a large number of experiments to be conducted under varying conditions. Small‐scale upstream…”
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Rapid bacterial detection and identification of bacterial strains using machine learning methods integrated with a portable multichannel fluorometer
Published in IEEE access (01-01-2023)“…Rapid and sensitive bioburden detection is of paramount importance in different applications including public health, and food and water safety. To overcome…”
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Study on low-cost calibration-free pH sensing with disposable optical sensors
Published in Analytica chimica acta (13-07-2012)“…[Display omitted] ► Development of disposable calibration-free optical pH sensor. ► Derivation of theoretical calibration model. ► Strategy to eliminate…”
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Comparisons of optical pH and dissolved oxygen sensors with traditional electrochemical probes during mammalian cell culture
Published in Biotechnology and bioengineering (01-07-2007)“…Small-scale upstream bioprocess development often occurs in flasks and multi-well plates. These culturing platforms are often not equipped to accurately…”
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Point-of-care production of therapeutic proteins of good-manufacturing-practice quality
Published in Nature biomedical engineering (01-09-2018)“…Manufacturing technologies for biologics rely on large, centralized, good-manufacturing-practice (GMP) production facilities and on a cumbersome…”
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Validation of an optical sensor-based high-throughput bioreactor system for mammalian cell culture
Published in Journal of biotechnology (10-04-2006)“…Cell culture optimization is a labor-intensive process requiring a large number of experiments to be conducted under varying conditions. Here we describe a…”
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Low-cost noninvasive optical CO2 sensing system for fermentation and cell culture
Published in Biotechnology and bioengineering (05-02-2005)“…High‐throughput bioprocessing is a very promising technique for bioprocess development and optimization because of its high efficiency. The key to its…”
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On the Possibility of Real-Time Monitoring of Glucose in Cell Culture by Microdialysis Using a Fluorescent Glucose Binding Protein Sensor
Published in Biotechnology progress (01-05-2008)“…Although glucose sensors with millimolar sensitivity are still the norm, there is now a developing interest in glucose sensors with micromolar sensitivity for…”
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Non-Invasive Optical Sensor Based Approaches for Monitoring Virus Culture to Minimize BSL3 Laboratory Entry
Published in Sensors (Basel, Switzerland) (24-06-2015)“…High titers of infectious viruses for vaccine and diagnostic reference panel development are made by infecting susceptible mammalian cells. Laboratory…”
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High-stability non-invasive autoclavable naked optical CO2 sensor
Published in Biosensors & bioelectronics (01-07-2003)“…The fabrication and characterization of a high-stability non-invasive autoclavable naked optical CO(2) sensor is described in this report. The sensor was made…”
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A Low-Cost Fluorescent Sensor for pCO2 Measurements
Published in Chemosensors (01-06-2014)“…Global warming is believed to be caused by increasing amounts of greenhouse gases (mostly CO2) discharged into the environment by human activity. In addition…”
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Genetically engineered binding proteins as biosensors for fermentation and cell culture
Published in Biotechnology and bioengineering (20-12-2003)“…The signal-transduction properties and the potential applications of two engineered binding proteins from E. coli were extensively studied. Both proteins have…”
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Reinventing shake flask fermentation: The breathable flask
Published in Biotechnology and bioengineering (01-09-2024)“…Cultivating cells in shake flasks is a routine operation that is largely unchanged since its inception. A glass or plastic Erlenmeyer vessel with the primary…”
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Transdermal sensing: in-situ non-invasive techniques for monitoring of human biochemical status
Published in Current opinion in biotechnology (01-10-2021)“…[Display omitted] Improving life expectancy necessitates prevention and early diagnosis of any disease state based on active self-monitoring of symptoms and…”
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