Search Results - "Ge, Shili"

T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals by Jordan, Stanley C., Shin, Bong-Ha, Gadsden, Terry-Ann M., Chu, Maggie, Petrosyan, Anna, Le, Catherine N., Zabner, Rachel, Oft, Jillian, Pedraza, Isabel, Cheng, Susan, Vo, Ashley, Ammerman, Noriko, Plummer, Jasmine, Ge, Shili, Froch, Max, Berg, Anders, Toyoda, Mieko, Zhang, Ruan

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Infectious Complications in Kidney-Transplant Recipients Desensitized with Rituximab and Intravenous Immunoglobulin by Kahwaji, Joseph, Sinha, Aditi, Toyoda, Mieko, Ge, Shili, Reinsmoen, Nancy, Cao, Kai, Lai, Chih-Hung, Villicana, Rafael, Peng, Alice, Jordan, Stanley, Vo, Ashley

“…Rituximab and intravenous Ig (IVIG) are commonly used for desensitization of HLA and blood group-incompatible (ABOi) transplants. However, serious infections…”
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Impact of Desensitization on Antiviral Immunity in HLA-Sensitized Kidney Transplant Recipients by Petrosyan, Anna, Vo, Ashley, Choi, Jua, Peng, Alice, Kahwaji, Joseph, Jordan, Stanley C., Chao, Christine, Rodriguez, Edgar, Chu, Maggie, Thomas, David, Mirocha, James, Ge, Shili, Shin, Bong-Ha, Toyoda, Mieko, Galera, Odette A.

“…Viral infections represent significant morbidity and mortality factors in kidney transplant recipients, with CMV, EBV, and BKV infections being most common…”
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A Phase I/II Trial of the Interleukin-6 Receptor–Specific Humanized Monoclonal (Tocilizumab) + Intravenous Immunoglobulin in Difficult to Desensitize Patients by Vo, Ashley A, Choi, Jua, Kim, Irene, Louie, Sabrina, Cisneros, Kristen, Kahwaji, Joseph, Toyoda, Mieko, Ge, Shili, Haas, Mark, Puliyanda, Dechu, Reinsmoen, Nancy, Peng, Alice, Villicana, Rafael, Jordan, Stanley C

“…BACKGROUNDCurrent desensitization (DES) methods are not always effective. Thus, novel, more effective approaches are desirable. Interleukin (IL)-6 is an…”
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Regulation of Anti-HLA Antibody-Dependent Natural Killer Cell Activation by Immunosuppressive Agents by Shin, Bong-Ha, Ge, Shili, Mirocha, James, Karasyov, Artur, Vo, Ashley, Jordan, Stanley C., Toyoda, Mieko

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Imlifidase Inhibits HLA Antibody-mediated NK Cell Activation and Antibody-dependent Cell-mediated Cytotoxicity (ADCC) In Vitro by Ge, Shili, Chu, Maggie, Choi, Jua, Louie, Sabrina, Vo, Ashley, Jordan, Stanley C., Toyoda, Mieko

“…BACKGROUND:Antibody-dependent cell-mediated cytotoxicity (ADCC) is an important pathway responsible for antibody-mediated rejection (AMR). Imlifidase (IdeS)…”
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Compassionate Use of Tocilizumab for Treatment of SARS-CoV-2 Pneumonia by Jordan, Stanley C, Zakowski, Phillip, Tran, Hai P, Smith, Ethan A, Gaultier, Cyril, Marks, Gregory, Zabner, Rachel, Lowenstein, Hayden, Oft, Jillian, Bluen, Benjamin, Le, Catherine, Shane, Rita, Ammerman, Noriko, Vo, Ashley, Chen, Peter, Kumar, Sanjeev, Toyoda, Mieko, Ge, Shili, Huang, Edmund

“…Abstract Background Preliminary data from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia patients indicate that a cytokine storm may…”
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IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation by Jordan, Stanley C, Lorant, Tomas, Choi, Jua, Kjellman, Christian, Winstedt, Lena, Bengtsson, Mats, Zhang, Xiaohai, Eich, Torsten, Toyoda, Mieko, Eriksson, Britt-Marie, Ge, Shili, Peng, Alice, Järnum, Sofia, Wood, Kathryn J, Lundgren, Torbjorn, Wennberg, Lars, Bäckman, Lars, Larsson, Erik, Villicana, Rafael, Kahwaji, Joe, Louie, Sabrina, Kang, Alexis, Haas, Mark, Nast, Cynthia, Vo, Ashley, Tufveson, Gunnar

“…In this study, an IgG-degrading enzyme derived from Streptococcus pyogenes (IdeS) that cleaves human IgG into F(ab′) 2 and Fc fragments reduced or eliminated…”
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Benefits of Rituximab Combined With Intravenous Immunoglobulin for Desensitization in Kidney Transplant Recipients by Vo, Ashley A, Choi, Jua, Cisneros, Kristen, Reinsmoen, Nancy, Haas, Mark, Ge, Shili, Toyoda, Mieko, Kahwaji, Joseph, Peng, Alice, Villicana, Rafael, Jordan, Stanley C

“…BACKGROUNDHighly HLA-sensitized (HS) patients have difficulty accessing compatible donors, especially deceased donor (DD) transplants. Desensitization…”
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Ontogeny of expression of transforming growth factor-β and its receptors and their possible relationship with scarless healing in human fetal skin by Chen, Wei, Fu, Xiaobing, Ge, Shili, Sun, Tongzhu, Zhou, Gang, Jiang, Duyin, Sheng, Zhiyong

“…Fetal cutaneous wounds that occur in early gestation heal without scar formation. Although much work has been done to characterize the role of transforming…”
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Plasma Exosomes From HLA-Sensitized Kidney Transplant Recipients Contain mRNA Transcripts Which Predict Development of Antibody-Mediated Rejection by Zhang, Hao, Huang, Edmund, Kahwaji, Joseph, Nast, Cynthia C, Li, Ping, Mirocha, James, Thomas, David L, Ge, Shili, Vo, Ashley A, Jordan, Stanley C, Toyoda, Mieko

“…BACKGROUNDSensitization to HLA remains a significant immunologic barrier to successful transplantation. Identifying immune mechanisms responsible for…”
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Clazakizumab for desensitization in highly sensitized patients awaiting transplantation by Vo, Ashley A., Huang, Edmund, Ammerman, Noriko, Toyoda, Mieko, Ge, Shili, Haas, Mark, Zhang, Xiaohai, Peng, Alice, Najjar, Reiad, Williamson, Summer, Myers, Catherine, Sethi, Supreet, Lim, Kathlyn, Choi, Jua, Gillespie, Matthew, Tang, Jacqueline, Jordan, Stanley C.

“…Alloantibodies are a significant barrier to successful transplantation. While desensitization has emerged, efficacy is limited. Interleukin‐6 (IL‐6) is an…”
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CLAZAKIZUMAB® (ANTI-IL-6) FOR DESENSITIZATION OF HIGHLY-HLA SENSITIZED PATIENTS AWAITING KIDNEY TRANSPLANT (NCT03380962) by Vo, Ashley, Ammerman, Noriko, Huang, Edmund, Toyoda, Mieko, Ge, Shili, Peng, Alice, Najjar, Reiad, Williamson, Summer, Myers, Catherine, Sethi, Supreet, Lim, Kathlyn, Choi, Jua, Jordan, Stanley

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CLAZAKIZUMAB (ANTI-IL-6) INDUCES FOXP3+ TREGS IN HIGHLY HLA SENSITIZED PATIENTS RECEIVING HLAI KIDNEY TRANSPLANTATION (NCT03380962) by Jordan, Stanley, Ge, Shili, Ammerman, Nori, Toyoda, Mieko, Huang, Edmund, Peng, Alice, Najjar, Reiad, Sethi, Supreet, Williamson, Summer, Myers, Kate, Lim, Kathlyn, Choi, Jua, Vo, Ashley A.

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Viral‐specific cytotoxic T‐cell responses in HLA‐sensitized kidney transplant patients maintained on everolimus and low‐dose tacrolimus by Ge, Shili, Chu, Maggie, Tang, Jacqueline, Kahwaji, Joseph, Karasyov, Artur, Lovato, Darly, Vo, Ashley, Choi, Jua, Jordan, Stanley C., Zhang, Ruan, Toyoda, Mieko

“…Background Maintenance with “everolimus + reduced dose tacrolimus” (Ev + Taclow) was reported to reduce the risk of viral infections compared to “tacrolimus +…”
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CLAZAKIZUMAB (ANTI-IL-6 MONOCLONAL) TREATMENT OF PATIENTS WITH CHRONIC & ACTIVE ANTIBODY-MEDIATED REJECTION POST-KIDNEY TRANSPLANTATION (NCT03380377) by Jordan, Stanley, Ammerman, Noriko, Toyoda, Mieko, Ge, Shili, Huang, Edmund, Peng, Alice, Sethi, Supreet, Najjar, Reiad, Ortiz, Edwin, Chu, Maggie, De Guzman, Abner, Kim, Irene, Lim, Kathlyn, Choi, Jua, Vo, Ashley A.

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Evaluation of Clazakizumab (Anti–Interleukin-6) in Patients With Treatment-Resistant Chronic Active Antibody-Mediated Rejection of Kidney Allografts by Jordan, Stanley C., Ammerman, Noriko, Choi, Jua, Huang, Edmund, Najjar, Reiad, Peng, Alice, Sethi, Supreet, Sandhu, Rana, Atienza, Janet, Toyoda, Mieko, Ge, Shili, Lim, Kathlyn, Gillespie, Matthew, Zhang, Xiaohai, Haas, Mark, Vo, Ashley

“…Interleukin-6 (IL-6) is an important mediator of inflammation and activation of T cells, B cells, and plasma cells. Excessive IL-6 production is linked to…”
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Cytomegalovirus Immunity After Alemtuzumab Induction in Desensitized Kidney Transplant Patients by Ge, Shili, Karasyov, Artur, Sinha, Aditi, Petrosyan, Anna, Lovato, Darly, Thomas, David L, Vo, Ashley, Jordan, Stan C, Toyoda, Mieko

“…BACKGROUNDDesensitization with IVIG + rituximab combined with alemtuzumab induction gives HLA-sensitized patients an opportunity for successful kidney…”
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Regulation of Anti-HLA Antibody-Dependent Natural Killer Cell Activation by Immunosuppressive Agents by Shin, Bong-Ha, Ge, Shili, Mirocha, James, Karasyov, Artur, Vo, Ashley, Jordan, Stanley C, Toyoda, Mieko

“…BACKGROUNDIt was demonstrated that human natural killer (NK) cells, via antibody-dependent cellular cytotoxicity (ADCC)-like mechanism, increase IFNγ…”
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Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection by Suviolahti, Elina, Ge, Shili, Nast, Cynthia C, Mirocha, James, Karasyov, Artur, White, Molly, Jordan, Stanley C, Toyoda, Mieko

“…Abstract Introduction Antibody-mediated rejection (ABMR) is dependent on complement activating donor-specific anti-HLA antibodies (DSA). This is commonly…”
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